2026 ICD-10-CM Diagnosis Code E83.51Hypocalcemia

ICD-10-CM Codes›E00–E89›E70-E88›E83

ICD-10-CM E83.51
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E83.51 is a billable ICD-10-CM diagnosis code for hypocalcemia. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 640 through 641. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E83.51
Billable Status
Yes — Valid for Submission
Code Describes
Hypocalcemia
Short Description
Hypocalcemia
Same as the full description in the CMS dataset.
Parent Code
E83.5
Disorders of calcium metabolism

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE83Disorders of mineral metabolism
This CodeE83.51Hypocalcemia

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Chronic myopathy with hypocalcemia and hypophosphatemia
  • Drug-induced hypocalcemia
  • Hypocalcemia
  • Hypocalcemia due to chronic kidney disease
  • Hypocalcemia of late pregnancy and/or lactation
  • Hypocalcemia of puerperium
  • Hypocalcemic rickets
  • Hypocalcemic tetany
  • Hypomagnesemia with secondary hypocalcemia
  • Iatrogenic hypocalcemia
  • Parathyroid hypocalcemic tetany
  • Serum calcium below reference range
  • Tetany

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • metabolism NOS
        • calcium
          • hypocalcemia
    • Hypocalcemia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hypocalcemia

    reduction of the blood calcium below normal. manifestations include hyperactive deep tendon reflexes, chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (dorland, 27th ed)

  • Tetany

    a disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. this condition is associated with unstable depolarization of axonal membranes, primarily in the peripheral nervous system. tetany usually results from hypocalcemia or reduced serum levels of magnesium that may be associated with hyperventilation; hypoparathyroidism; rickets; uremia; or other conditions. (from adams et al., principles of neurology, 6th ed, p1490)

  • Grade 1 Hypocalcemia, CTCAE|Grade 1 Hypocalcemia

    corrected serum calcium of

  • Grade 2 Hypocalcemia, CTCAE|Grade 2 Hypocalcemia

    corrected serum calcium of <8.0 - 7.0 mg/dl; <2.0 - 1.75 mmol/l; ionized calcium <1.0 - 0.9 mmol/l; symptomatic

  • Grade 3 Hypocalcemia, CTCAE|Grade 3 Hypocalcemia

    corrected serum calcium of <7.0 - 6.0 mg/dl; <1.75 - 1.5 mmol/l; ionized calcium <0.9 - 0.8 mmol/l; hospitalization indicated

  • Familial Hypercalciuric Hypocalcemia

    a hereditary condition caused by calcium sensing receptor gene mutations, resulting in calcium-hypersensitivity, and compensatory hypocalcemia and hypercalciuria.

  • Grade 1 Hypocalcemia, CTCAE|Grade 1 Hypocalcemia

    corrected serum calcium of

  • Grade 2 Hypocalcemia, CTCAE|Grade 2 Hypocalcemia

    corrected serum calcium of <8.0-7.0 mg/dl; <2.0-1.75 mmol/l; ionized calcium <1.0-0.9 mmol/l; symptomatic

  • Grade 3 Hypocalcemia, CTCAE|Grade 3 Hypocalcemia

    corrected serum calcium of <7.0-6.0 mg/dl; <1.75-1.5 mmol/l; ionized calcium <0.9-0.8 mmol/l; hospitalization indicated

  • Grade 4 Hypocalcemia, CTCAE|Grade 4 Hypocalcemia

    corrected serum calcium of <6.0 mg/dl; <1.5 mmol/l; ionized calcium <0.8 mmol/l; life-threatening consequences

  • Grade 5 Hypocalcemia, CTCAE|Grade 5 Hypocalcemia

    death

  • Hypocalcemia

    lower than normal levels of calcium in the circulating blood.

  • Hypocalcemia, CTCAE|Hypocalcemia|Hypocalcemia

    a disorder characterized by laboratory test results that indicate a low concentration of calcium (corrected for albumin) in the blood.

  • TRPM6 wt Allele|CHAK2|FLJ22628|HMGX|HOMG|HOMG1|HSH|Hypomagnesemia, Secondary Hypocalcemia Gene|Transient Receptor Potential Cation Channel Subfamily M Member 6 wt Allele|Transient Receptor Potential Cation Channel, Subfamily M, Member 6 Gene

    human trpm6 wild-type allele is located in the vicinity of 9q21.13 and is approximately 166 kb in length. this allele, which encodes transient receptor potential cation channel subfamily m member 6 protein, is involved in both magnesium homeostasis and protein phosphorylation. mutation of the gene is associated with hypomagnesemia.

  • Tetany

    sudden and involuntary contraction of a muscle of group of muscles due to hypocalcemia.

Patient EducationClinical

Calcium

Calcium is a mineral, a nutrient that you need (in small amounts) to keep your body healthy. You have more calcium in your body than any other mineral.

The full article covers:

  • What is calcium and why do I need it?
  • How do I get calcium?
  • How much calcium do I need?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E83.51 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
275.41 Hypocalcemia
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E83.51Overview

Is E83.51 (Disorders of calcium metabolism) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hypocalcemia on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E83.51 group to?

When hypocalcemia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 640, 641, with relative weights from 0.7782 to 1.3356 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E83.51?

Under the General Equivalence Mappings, hypocalcemia converts to ICD-9-CM 275.41 (hypocalcemia). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.