2027 ICD-10-CM Diagnosis Code E83.110Hereditary hemochromatosis
ICD-10-CM Codes›E00–E89›E70-E88›E83
- Billable — Valid for Submission
- Chronic Condition
E83.110 is a billable ICD-10-CM diagnosis code for hereditary hemochromatosis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 642. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.
E83.110 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 23 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 23, ESRD (V21) category 23, ESRD (V24) category 23, and RxHCC Part D (V08) category 43 for payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
E83.110 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Bronze diabetes
- Digenic hemochromatosis
- Ferroportin disease
- FTH1-related iron overload
- Hemochromatosis type 1
- Hemochromatosis type 3
- Hemochromatosis type 4
- Hereditary hemochromatosis
- Hypochromic microcytic anemia with iron overload
- Juvenile hemochromatosis
- Microcytic hypochromic anemia
- Pigment cirrhosis
- Primary hemochromatosis
- SLC40A1-related hemochromatosis
- Symptomatic form of hemochromatosis type 1
- Type 2A juvenile hereditary hemochromatosis
- Type 2B juvenile hereditary hemochromatosis
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E83.110: its own notes plus those printed at E83.11, E83.1, E83, block E70-E88, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Bronzed diabetes
- Pigmentary cirrhosis (of liver)
- Primary (hereditary) hemochromatosis
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- Ehlers-Danlos syndromes (Q79.6-)
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name E83.110, its category, or a range that includes it.
Excludes1 4
These codes carry an Excludes1 note naming E83.110: they are not reported together with it, unless the two conditions are unrelated.
- K74 Fibrosis and cirrhosis of liverpigmentary cirrhosis (of liver) (E83.110)
- E61 Deficiency of other nutrient elementsdisorders of mineral metabolism (E83.-) names E83.-, which includes this code
- P78.84 Gestational alloimmune liver diseasehemochromatosis (E83.11-) names E83.11-, which includes this code
- R79.0 Abnormal level of blood mineraldisorders of mineral metabolism (E83.-) names E83.-, which includes this code
Excludes2 2
These codes carry an Excludes2 note naming E83.110: its condition is not part of those codes, and both may be reported when the patient has both.
- K76 Other diseases of liverpigmentary cirrhosis (of liver) (E83.110)
- Block K70-K77 Diseases of liverhemochromatosis (E83.11-) names E83.11-, which includes this code
Code First 2
These codes say to code first a condition named in the note, and E83.110 is one of the conditions named.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
hereditary (primary) E83.110
primary E83.110
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Hereditary Hemochromatosis
an inherited metabolic disorder characterized by iron accumulation in the tissues.Hemochromatosis
a disorder of iron metabolism characterized by a triad of hemosiderosis; liver cirrhosis; and diabetes mellitus. it is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (jablonski's dictionary of syndromes & eponymic diseases, 2d ed)
Patient EducationClinical
Hemochromatosis
Hemochromatosis is a disease in which too much iron builds up in your body. Your body needs iron but too much of it is toxic. If you have hemochromatosis, you absorb more iron than you need. Your body has no natural way to get rid of the extra iron. It stores it in body tissues, especially the liver, heart, and pancreas.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E83.110 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E83.110Overview
What is the ICD-10 code for hereditary hemochromatosis?
The ICD-10-CM code for hereditary hemochromatosis is E83.110 (sometimes written as E83110). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E83.110 (Hemochromatosis) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report hereditary hemochromatosis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E83.110 group to?
When hereditary hemochromatosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 642 (inborn and Other Disorders of Metabolism), which carries a relative weight of 1.3226. Higher weights mean higher Medicare reimbursement.
Can E83.110 be reported with P78.84?
Not as a rule. The Excludes1 note at E83.11, which applies to E83.110, lists "GALD (P78.84)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of E83.110?
Under the General Equivalence Mappings, hereditary hemochromatosis converts to ICD-9-CM 275.01 (heredit hemochromatosis). The mapping is a direct match.
Does E83.110 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage. E83.110 mapped to HCC 23 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 23 (Other Significant Endocrine and Metabolic Disorders), ESRD (V21) category 23 (Other Significant Endocrine and Metabolic Disorders), ESRD (V24) category 23 (Other Significant Endocrine and Metabolic Disorders), and RxHCC Part D (V08) category 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders).
