2026 ICD-10-CM Diagnosis Code E70.328Other oculocutaneous albinism
ICD-10-CM Codes›E00–E89›E70-E88›E70
- Billable — Valid for Submission
- Chronic Condition
E70.328 is a billable ICD-10-CM diagnosis code for other oculocutaneous albinism. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as cross syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Cross syndrome
- Oculocerebral hypopigmentation syndrome of Preus type
- Oculocutaneous albinism type 4
- Oculocutaneous albinism type 5
- Oculocutaneous albinism type 6
- Oculocutaneous albinism type 7
- Oculocutaneous albinism type 8
- Punctate oculocutaneous albinoidism
- Tyrosinase-positive oculocutaneous albinism
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Cross syndrome
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- other specified - E70.328
- Cross syndrome - E70.328
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Albinism, albino
- oculocutaneous
- other specified
- Cross syndrome
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
OCA2 wt Allele|BEY|BEY1|BEY2|BOCA|D15S12|EYCL|EYCL2|EYCL3|Eye Color 2 (Central Brown) Gene|Eye Color 3 (Brown) Gene|HCL3|Hair Color 3 (Brown) Gene|OCA2 Melanosomal Transmembrane Protein wt Allele|Oculocutaneous Albinism II (Pink-Eye Dilution Homolog, Mouse) Gene|Oculocutaneous Albinism II Gene|P|P Gene|PED|Pink-Eyed Dilution Gene|SHEP1|Total Brown Iris Pigmentation Gene
human oca2 wild-type allele is located within 15q12-q13.1 and is approximately 344 kb in length. this allele, which encodes p protein, is involved in eye and skin color. mutations in this gene are associated with type 2 oculocutaneous albinism.OCA5 Gene|Albinism, Oculocutaneous, Type VII Gene|OCA5|OCA5|OCA5|OCA7|Oculocutaneous Albinism 5 (Autosomal Recessive) Gene
human oca5 gene is located within 4q24 and the size of this phenotypic locus is not reported. this gene region has no known protein product. autosomal recessive mutation of the gene is associated with oculocutaneous albinism 5.Oculocutaneous Albinism
an autosomal recessive inherited disorder caused by mutations of the oca2, slc45a2, tyr and tyrp1 genes. it is characterized by hypopigmentation of the skin, hair, and eyes, resulting in very fair skin, white colored hair, and reduced pigmentation in the iris and retina. individuals may have vision disturbances and photophobia.Oculocutaneous Albinism Type 1A|OCA1A
oculocutaneous albinism inherited in an autosomal recessive pattern, and caused by mutation(s) in the tyr gene, encoding tyrosinase.SLC24A5 wt Allele|JSX|NCKX5|OCA6|Oculocutaneous Albinism 6 (Autosomal Recessive) Gene|SHEP4|Solute Carrier Family 24 (Sodium/Potassium/Calcium Exchanger), Member 5 Gene|Solute Carrier Family 24 Member 5 wt Allele|Solute Carrier Family 24, Member 5 Gene
human slc24a5 wild-type allele is located in the vicinity of 15q21.1 and is approximately 22 kb in length. this allele, which encodes sodium/potassium/calcium exchanger 5 protein, is involved in melanosome pigmentation. mutation of the gene is associated with oculocutaneous albinism type 6.TYR wt Allele|ATN|CMM8|OCA1|OCA1A|OCAIA|SHEP3|Tyrosinase (Oculocutaneous Albinism IA) Gene|Tyrosinase wt Allele
human tyr wild-type allele is located within 11q14-q21 and is approximately 118 kb in length. this allele, which encodes tyrosinase protein, plays a role in the multi-step biosynthesis of melanin from tyrosine. allelic variants of the tyr gene cause three different types of oculocutaneous albinism.
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Convert E70.328 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E70.328Overview
Is E70.328 (Oculocutaneous albinism) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other oculocutaneous albinism on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What is the ICD-9 equivalent of E70.328?
Under the General Equivalence Mappings, other oculocutaneous albinism converts to ICD-9-CM 270.2 (arom amin-acid metab NEC). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
