2026 ICD-10-CM Diagnosis Code E03.2Hypothyroidism due to medicaments and other exogenous substances

ICD-10-CM Codes›E00–E89›E00-E07›E03

ICD-10-CM E03.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E03.2 is a billable ICD-10-CM diagnosis code for hypothyroidism due to medicaments and other exogenous substances. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Thyroid disorders.

Code Identity

ICD-10-CM Code
E03.2
Billable Status
Yes — Valid for Submission
Code Describes
Hypothyroidism due to medicaments and other exogenous substances
Short Description
Hypothyroidism due to meds and oth exogenous substances
Parent Code
E03
Other hypothyroidism

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE00-E07Disorders of thyroid gland
CategoryE03Other hypothyroidism
This CodeE03.2Hypothyroidism due to medicaments and other exogenous substances

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired central hypothyroidism
  • Central hypothyroidism
  • Drug induced acquired central hypothyroidism
  • Hypothyroidism caused by amiodarone
  • Hypothyroidism caused by drug
  • Hypothyroidism caused by iodide excess
  • Hypothyroidism caused by resorcinol
  • Hypothyroidism resulting from para-aminosalicylic acid
  • Hypothyroidism resulting from phenylbutazone
  • Iatrogenic hypothyroidism

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Code First

  • poisoning due to drug or toxin, if applicable T36 T65

Use Additional Code

  • code for adverse effect, if applicable, to identify drug T36 T50

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Hypothyroidism(acquired)
      • due to
        • exogenous substance NEC
    • Hypothyroidism(acquired)
      • due to
        • medicament NEC
    • Hypothyroidism(acquired)
      • due to
        • P-aminosalicylic acid (PAS)
    • Hypothyroidism(acquired)
      • due to
        • phenylbutazone
    • Hypothyroidism(acquired)
      • due to
        • resorcinol
    • Hypothyroidism(acquired)
      • due to
        • sulfonamide
    • Hypothyroidism(acquired)
      • due to
        • thiourea group drugs
    • Hypothyroidism(acquired)
      • iatrogenic NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR END001
Thyroid disorders
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Acquired Central Hypothyroidism

    central hypothyroidism, the cause of which is not present at birth.

Patient EducationClinical

Hypothyroidism

Hypothyroidism, or underactive thyroid, happens when your thyroid gland doesn't make enough thyroid hormones to meet your body's needs.

The full article covers:

  • What is hypothyroidism?
  • What causes hypothyroidism?
  • Who is at risk for hypothyroidism?
  • What are the symptoms of hypothyroidism?
  • What other problems can hypothyroidism cause?
  • How is hypothyroidism diagnosed?
  • What are the treatments for hypothyroidism?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E03.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
244.2 Iodine hypothyroidism
Approximate The match is approximate rather than exact.
ICD-9-CM
244.3 Iatrogen hypothyroid NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E03.2Overview

Is E03.2 (Other hypothyroidism) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hypothyroidism due to medicaments and other exogenous substances on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E03.2 group to?

When hypothyroidism due to medicaments and other exogenous substances is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E03.2?

Under the General Equivalence Mappings, hypothyroidism due to medicaments and other exogenous substances converts to ICD-9-CM 244.2 (iodine hypothyroidism) and 244.3 (iatrogen hypothyroid NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.