2027 ICD-10-CM Diagnosis Code D75.84Other platelet-activating anti-PF4 disorders
ICD-10-CM Codes›D50–D89›D70-D77›D75
- Billable — Valid for Submission
- Risk Adjusts — HCC 112
- Chronic Condition
D75.84 is a billable ICD-10-CM diagnosis code for other platelet-activating anti-PF4 disorders. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793, 813. Coders also document this condition as adverse reaction to COVID-19 non-replicating viral vector vaccine. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.
For Medicare Advantage risk adjustment, D75.84 maps to CMS-HCC Category 112 (Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions) under the V28 model, adding a risk factor of about 0.450 for a community, non-dual, aged beneficiary in payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
D75.84 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Adverse reaction to COVID-19 non-replicating viral vector vaccine
- Adverse reaction to COVID-19 vaccine
- Thrombosis with thrombocytopenia syndrome following vaccination
- TTS following non-replicating adenovirus vector COVID-19 vaccination
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to D75.84: its own notes plus those printed at D75 and Chapter 3. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Spontaneous heparin-induced thrombocytopenia syndrome (without heparin exposure)
- Thrombosis with thrombocytopenia syndrome
- Vaccine-induced thrombotic thrombocytopenia
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code, if applicable, for adverse effect of other viral vaccine (T50.B95-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disorder (of) See Also: Disease;
Syndrome See Also: Disease;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Platelet Disorders
Platelets, also known as thrombocytes, are blood cells. They form in your bone marrow, a sponge-like tissue in your bones. Platelets play a major role in blood clotting. Normally, when one of your blood vessels is injured, you start to bleed.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Code History & ChangesHistory
Replacement D75.84 replaces the following previously assigned code(s):
- D75.89 - Other specified diseases of blood and blood-forming organs
Questions About D75.84Overview
What is the ICD-10 code for other platelet-activating anti-PF4 disorders?
The ICD-10-CM code for other platelet-activating anti-PF4 disorders is D75.84 (sometimes written as D7584). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is D75.84 (Other specified diseases of blood and blood-forming organs) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other platelet-activating anti-PF4 disorders on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does D75.84 group to?
When other platelet-activating anti-PF4 disorders is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 813, with relative weights from 1.5279 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.
Does D75.84 need an additional code?
When the condition applies, yes. The Use Additional Code note reads: code, if applicable, for adverse effect of other viral vaccine (T50.B95-). The additional code is reported after D75.84.
What HCC is D75.84?
D75.84 (other platelet-activating anti-PF4 disorders) maps to CMS-HCC Category 112 (Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions), commonly written as HCC 112, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 48 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.
Does D75.84 risk-adjust for Medicare Advantage payment?
Yes. When documented and reported on a Medicare Advantage encounter, D75.84 adds a risk adjustment factor of about 0.450 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.450 to 0.708 depending on the payment segment). A more severe related category (HCC 111) supersedes it when both are reported. See the full factor table on the HCC 112 category page.
