2026 ICD-10-CM Diagnosis Code D75.84Other platelet-activating anti-PF4 disorders

ICD-10-CM CodesD50–D89D70-D77D75

ICD-10-CM D75.84
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D75.84 is a billable ICD-10-CM diagnosis code for other platelet-activating anti-PF4 disorders. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as adverse reaction to COVID-19 non-replicating viral vector vaccine. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.

Code Identity

ICD-10-CM Code
D75.84
Billable Status
Yes — Valid for Submission
Code Describes
Other platelet-activating anti-PF4 disorders
Short Description
Other platelet-activating anti-PF4 disorders
Same as the full description in the CMS dataset.
Parent Code
Other specified diseases of blood and blood-forming organs

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD75Other and unspecified diseases of blood and blood-forming organs
This CodeD75.84Other platelet-activating anti-PF4 disorders

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Adverse reaction to COVID-19 non-replicating viral vector vaccine
  • Adverse reaction to COVID-19 vaccine
  • Thrombosis with thrombocytopenia syndrome following vaccination
  • TTS following non-replicating adenovirus vector COVID-19 vaccination

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Spontaneous heparin-induced thrombocytopenia syndrome (without heparin exposure)
  • Thrombosis with thrombocytopenia syndrome
  • Vaccine-induced thrombotic thrombocytopenia

Use Additional Code

  • code, if applicable, for adverse effect of other viral vaccine T50.B95

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • platelet-activating anti-PF4, specified NEC
    • Syndrome
      • thrombosis with thrombocytopenia
    • Thrombocytopenia, thrombocytopenic
      • heparin induced (HIT)
        • syndrome
          • spontaneous (without heparin exposure)
    • Thrombocytopenia, thrombocytopenic
      • vaccine-induced thrombotic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD006
Coagulation and hemorrhagic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Code History & ChangesHistory

Replacement D75.84 replaces the following previously assigned code(s):

  • D75.89 - Other specified diseases of blood and blood-forming organs
FY 2023AddedAdded to the ICD-10-CM code setEffective October 1, 2022.
FY 2024–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D75.84Overview

Is D75.84 (Other specified diseases of blood and blood-forming organs) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other platelet-activating anti-PF4 disorders on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.