2027 ICD-10-CM Diagnosis Code D75.828Other heparin-induced thrombocytopenia syndrome

ICD-10-CM Codes›D50–D89›D70-D77›D75

ICD-10-CM D75.828
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D75.828 is a billable ICD-10-CM diagnosis code for other heparin-induced thrombocytopenia syndrome. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793, 813. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.

D75.828 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 48 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 48, ESRD (V21) category 48, and ESRD (V24) category 48 for payment year 2027.

Code Identity

ICD-10-CM Code
D75.828
Billable Status
Yes — Valid for Submission
Code Describes
Other heparin-induced thrombocytopenia syndrome
Short Description
Other heparin-induced thrombocytopenia syndrome
Same as the full description in the CMS dataset.
Parent Code
D75.82
Heparin induced thrombocytopenia (HIT)

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD75Other and unspecified diseases of blood and blood-forming organs
This CodeD75.828Other heparin-induced thrombocytopenia syndrome

Medicare Risk Adjustment (HCC)Billing

D75.828 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
Dropped in V28 see all codes that no longer risk-adjust
Prior Model (CMS-HCC V24)
HCC 48
V24 retired last contributed to a Medicare Advantage risk score in payment year 2025
Other CMS Models
PACE (CMS-HCC V22): HCC 48 · ESRD (V21): HCC 48 · ESRD (V24): HCC 48
ESRD V21 weights: 0.059 dialysis, 0.173–0.234 functioning graft · ESRD V24 weights: 0.063 dialysis, 0.192–0.358 functioning graft
Part D (RxHCC)
Not mapped
D75.828 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D75.828: its own notes plus those printed at D75.82, D75, and Chapter 3. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Autoimmune heparin-induced thrombocytopenia syndrome
  • Delayed-onset heparin-induced thrombocytopenia
  • Persisting heparin-induced thrombocytopenia

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From D75 Other and unspecified diseases of blood and blood-forming organs applies to 13 codes
  • acute lymphadenitis (L04.-)
  • chronic lymphadenitis (I88.1)
  • enlarged lymph nodes (R59.-)
  • hypergammaglobulinemia NOS (D89.2)
  • lymphadenitis NOS (I88.9)
  • mesenteric lymphadenitis (acute) (chronic) (I88.0)
From Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From D75.82 Heparin induced thrombocytopenia (HIT) applies to 4 codes
  • code, if applicable, for adverse effect of heparin (T45.515-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D75.828, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming D75.828: they are not reported together with it, unless the two conditions are unrelated.

  • D68.6 Other thrombophilia
    heparin induced thrombocytopenia (HIT) (D75.82-) names D75.82-, which includes this code
  • D69.5 Secondary thrombocytopenia
    heparin induced thrombocytopenia (HIT) (D75.82-) names D75.82-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD006
Coagulation and hemorrhagic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Heparin Induced Thrombocytopenia

    a life-threatening complication of heparin therapy. it results in immune-mediated thrombocytopenia and, in 25-50 percent of the patients, thrombotic complications.

Patient EducationClinical

Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

The full article covers:

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  • How can I stay safe when taking medicines?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement D75.828 replaces the following previously assigned code(s):

  • D75.82 - Heparin induced thrombocytopenia (HIT)
FY 2023AddedAdded to the ICD-10-CM code setEffective October 1, 2022.
FY 2024–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D75.828Overview

What is the ICD-10 code for other heparin-induced thrombocytopenia syndrome?

The ICD-10-CM code for other heparin-induced thrombocytopenia syndrome is D75.828 (sometimes written as D75828). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D75.828 (Heparin induced thrombocytopenia (HIT)) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other heparin-induced thrombocytopenia syndrome on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D75.828 group to?

When other heparin-induced thrombocytopenia syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 813, with relative weights from 1.5279 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Does D75.828 need an additional code?

When the condition applies, yes. The Use Additional Code note at D75.82, which applies to D75.828, reads: code, if applicable, for adverse effect of heparin (T45.515-). The additional code is reported after D75.828.

Does D75.828 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage. D75.828 mapped to HCC 48 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 48 (Coagulation Defects and Other Specified Hematological Disorders), ESRD (V21) category 48 (Coagulation Defects and Other Specified Hematological Disorders), and ESRD (V24) category 48 (Coagulation Defects and Other Specified Hematological Disorders).