2024 ICD-10-CM Diagnosis Code T45.515

Adverse effect of anticoagulants

ICD-10-CM Code:
T45.515
ICD-10 Code for:
Adverse effect of anticoagulants
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified
        (T45)

T45.515 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of anticoagulants. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of anticoagulants

Non-specific codes like T45.515 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of anticoagulants:

  • Use T45.515A for initial encounter - BILLABLE CODE

  • Use T45.515D for subsequent encounter - BILLABLE CODE

  • Use T45.515S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acenocoumarol adverse reaction
  • Adverse reaction to coumarin
  • Adverse reaction to danaparoid
  • Adverse reaction to indanedione
  • Anticoagulant adverse reaction
  • Coumarin necrosis
  • Dalteparin adverse reaction
  • Dermatosis caused by coumarin
  • Dermatosis caused by coumarin
  • Dermatosis resulting from anticoagulant therapy
  • Direct acting anticoagulant adverse reaction
  • Enoxaparin adverse reaction
  • Heparin adverse reaction
  • Heparinoid adverse reaction
  • Indirect acting anticoagulant adverse reaction
  • Pesticide adverse reaction
  • Phenindione adverse reaction
  • Tinzaparin adverse reaction
  • Transfusion reaction due to toxic effect of anticoagulant
  • Warfarin adverse reaction
  • Warfarin monitoring status
  • Warfarin side effects

Clinical Information

  • Acenocoumarol

    a coumarin that is used as an anticoagulant. its actions and uses are similar to those of warfarin. (from martindale, the extra pharmacopoeia, 30th ed, p233)
  • Phenindione

    an indandione that has been used as an anticoagulant. phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. (from martindale, the extra pharmacopoeia, 30th ed, p234)
  • Phenprocoumon

    coumarin derivative that acts as a long acting oral anticoagulant.
  • Warfarin

    an anticoagulant that acts by inhibiting the synthesis of vitamin k-dependent coagulation factors. warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. it is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. warfarin is also used as a rodenticide.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (T45). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AcenocoumarinT45.511T45.512T45.513T45.514T45.515T45.516
AcenocoumarolT45.511T45.512T45.513T45.514T45.515T45.516
AnisindioneT45.511T45.512T45.513T45.514T45.515T45.516
Anticoagulant NECT45.511T45.512T45.513T45.514T45.515T45.516
Anticoagulant NEC
  »Antagonist
T45.511T45.512T45.513T45.514T45.515T45.516
BishydroxycoumarinT45.511T45.512T45.513T45.514T45.515T45.516
BromindioneT45.511T45.512T45.513T45.514T45.515T45.516
CoumadinT45.511T45.512T45.513T45.514T45.515T45.516
Coumadin
  »rodenticide
T45.511T45.512T45.513T45.514T45.515T45.516
CoumarinT45.511T45.512T45.513T45.514T45.515T45.516
CoumetarolT45.511T45.512T45.513T45.514T45.515T45.516
CumetharolT45.511T45.512T45.513T45.514T45.515T45.516
DaniloneT45.511T45.512T45.513T45.514T45.515T45.516
Dicoumarol, dicoumarin, dicumarolT45.511T45.512T45.513T45.514T45.515T45.516
DiphenadioneT45.511T45.512T45.513T45.514T45.515T45.516
Diphenadione
  »rodenticide
T45.511T45.512T45.513T45.514T45.515T45.516
Drotrecogin alfaT45.511T45.512T45.513T45.514T45.515T45.516
Enoxaparin (sodium)T45.511T45.512T45.513T45.514T45.515T45.516
FluindioneT45.511T45.512T45.513T45.514T45.515T45.516
Heparin (sodium)T45.511T45.512T45.513T45.514T45.515T45.516
Heparin (sodium)
  »action reverser
T45.511T45.512T45.513T45.514T45.515T45.516
Heparin-fractionT45.511T45.512T45.513T45.514T45.515T45.516
Heparinoid (systemic)T45.511T45.512T45.513T45.514T45.515T45.516
Indandione (derivatives)T45.511T45.512T45.513T45.514T45.515T45.516
Indendione (derivatives)T45.511T45.512T45.513T45.514T45.515T45.516
NicoumaloneT45.511T45.512T45.513T45.514T45.515T45.516
PanwarfinT45.511T45.512T45.513T45.514T45.515T45.516
PhenindioneT45.511T45.512T45.513T45.514T45.515T45.516
PhenprocoumonT45.511T45.512T45.513T45.514T45.515T45.516
SintromT45.511T45.512T45.513T45.514T45.515T45.516
TioclomarolT45.511T45.512T45.513T45.514T45.515T45.516
WarfarinT45.511T45.512T45.513T45.514T45.515T45.516
Warfarin
  »rodenticide
T45.511T45.512T45.513T45.514T45.515T45.516
Warfarin
  »sodium
T45.511T45.512T45.513T45.514T45.515T45.516
XigrisT45.511T45.512T45.513T45.514T45.515T45.516
ZovantT45.511T45.512T45.513T45.514T45.515T45.516

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.