2027 ICD-10-CM Diagnosis Code D52.8Other folate deficiency anemias

ICD-10-CM Codes›D50–D89›D50-D53›D52

ICD-10-CM D52.8
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D52.8 is a billable ICD-10-CM diagnosis code for other folate deficiency anemias. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 811 through 812. Coders also document this condition as congenital folate malabsorption anemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nutritional anemia.

Code Identity

ICD-10-CM Code
D52.8
Billable Status
Yes — Valid for Submission
Code Describes
Other folate deficiency anemias
Short Description
Other folate deficiency anemias
Same as the full description in the CMS dataset.
Parent Code
D52
Folate deficiency anemia

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD50-D53Nutritional anemias
CategoryD52Folate deficiency anemia
This CodeD52.8Other folate deficiency anemias

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Congenital folate malabsorption anemia
  • Folate deficiency anemia due to liver disorders
  • Folate deficiency anemia due to malabsorption
  • Hereditary folate deficiency anemia
  • Megaloblastic anemia due to error of folate metabolism
  • Megaloblastic anemia due to inborn errors of metabolism

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D52.8: its own notes plus those printed at D52 and Chapter 3. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From D52 Folate deficiency anemia applies to 4 codes
  • folate deficiency without anemia (E53.8)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D52.8, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming D52.8: they are not reported together with it, unless the two conditions are unrelated.

  • E53.8 Deficiency of other specified B group vitamins
    folate deficiency anemia (D52.-) names D52.-, which includes this code

Excludes2 2

These codes carry an Excludes2 note naming D52.8: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block E40-E46 Malnutrition
    nutritional anemias (D50-D53) names D50-D53, which includes this code
  • Block E50-E64 Other nutritional deficiencies
    nutritional anemias (D50-D53) names D50-D53, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD001
Nutritional anemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Folate Deficiency Anemia

    anemia caused by folate deficiency.

Patient EducationClinical

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D52.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
281.2 Folate-deficiency anemia
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D52.8Overview

What is the ICD-10 code for other folate deficiency anemias?

The ICD-10-CM code for other folate deficiency anemias is D52.8 (sometimes written as D528). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D52.8 (Folate deficiency anemia) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other folate deficiency anemias on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D52.8 group to?

When other folate deficiency anemias is the principal diagnosis on an inpatient stay, it groups to MS-DRG 812, 811, with relative weights from 0.9237 to 1.3991 depending on complications. Higher weights mean higher Medicare reimbursement.

Can D52.8 be reported with E53.8?

Not as a rule. The Excludes1 note at D52, which applies to D52.8, lists "folate deficiency without anemia (E53.8)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of D52.8?

Under the General Equivalence Mappings, other folate deficiency anemias converts to ICD-9-CM 281.2 (folate-deficiency anemia). The mapping is approximate, so confirm the match fits the documentation.