Vitamin B12 deficiency anemia (D51) ICD-10-CM
The D51 code range covers vitamin b12 deficiency anemia with 7 ICD-10-CM diagnosis codes. 6 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
- deficiency of other B group vitamins E53
Codes in the D51 Range 7 codes · 6 billable
- D51 Vitamin B12 deficiency anemiaNon-billable
- D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency
- D51.1 Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria
- D51.2 Transcobalamin II deficiency
- D51.3 Other dietary vitamin B12 deficiency anemia
- D51.8 Other vitamin B12 deficiency anemias
- D51.9 Vitamin B12 deficiency anemia, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D51 range.
Pernicious Anemia
Megaloblastic anemia caused by vitamin B-12 deficiency due to impaired absorption. The impaired absorption of vitamin B-12 is secondary to atrophic gastritis and loss of gastric parietal cells.
Transcobalamin II Deficiency
An autosomal recessive condition caused by mutation(s) in the TCN2 gene, encoding transcobalamin-2. it is characterized by failure to thrive, megaloblastic anemia, and pancytopenia.
About the D51 Code Range
Vitamin B12 deficiency anemia belongs to the nutritional anemias, a group of blood disorders.
D51 separates the named forms by intrinsic factor deficiency, selective difficulty absorbing vitamin B12 with proteinuria, transcobalamin II deficiency, and dietary deficiency. Its subdivisions also include other vitamin B12 deficiency anemias and an unspecified form.
Questions About This Page
How many billable codes are in the D51 range?
Of the 7 codes in this range, 6 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the D51 range classify?
The range classifies vitamin b12 deficiency anemia. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
