2026 ICD-10-CM Diagnosis Code D38.5Neoplasm of uncertain behavior of other respiratory organs

ICD-10-CM CodesC00–D49D37-D48D38

ICD-10-CM D38.5
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D38.5 is a billable ICD-10-CM diagnosis code for neoplasm of uncertain behavior of other respiratory organs. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 180 through 182. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D38.5
Billable Status
Yes — Valid for Submission
Code Describes
Neoplasm of uncertain behavior of other respiratory organs
Short Description
Neoplasm of uncertain behavior of other respiratory organs
Same as the full description in the CMS dataset.
Parent Code
Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD38Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs
This CodeD38.5Neoplasm of uncertain behavior of other respiratory organs

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Glomangiopericytoma
  • Mass of petrous part of temporal bone
  • Neoplasm of cartilage of nose
  • Neoplasm of eustachian tube
  • Neoplasm of mastoid air cells
  • Neoplasm of mastoid antrum
  • Neoplasm of middle ear and mastoid
  • Neoplasm of nasal vestibule
  • Neoplasm of tympanic cavity
  • Neoplasm of uncertain behavior of accessory sinus
  • Neoplasm of uncertain behavior of cartilage of nose
  • Neoplasm of uncertain behavior of ear
  • Neoplasm of uncertain behavior of ethmoidal sinus
  • Neoplasm of uncertain behavior of eustachian tube
  • Neoplasm of uncertain behavior of frontal sinus
  • Neoplasm of uncertain behavior of mastoid air cells
  • Neoplasm of uncertain behavior of maxillary sinus
  • Neoplasm of uncertain behavior of middle ear
  • Neoplasm of uncertain behavior of nasal cavity
  • Neoplasm of uncertain behavior of nasal concha
  • Neoplasm of uncertain behavior of nose
  • Neoplasm of uncertain behavior of septum of nose
  • Neoplasm of uncertain behavior of sphenoidal sinus
  • Neoplasm of uncertain behavior of temporal bone
  • Neoplasm of uncertain behavior of tympanic antrum
  • Neoplasm of uncertain behavior of tympanic cavity
  • Neoplasm of uncertain behavior of upper respiratory tract
  • Neoplasm of uncertain behavior of vestibule of nose
  • Sinonasal glomangiopericytoma

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Neoplasm of uncertain behavior of accessory sinuses
  • Neoplasm of uncertain behavior of cartilage of nose
  • Neoplasm of uncertain behavior of middle ear
  • Neoplasm of uncertain behavior of nasal cavities

Type 1 Excludes

  • neoplasm of uncertain behavior of ear external skin D48.5
  • neoplasm of uncertain behavior of nose NOS D48.7
  • neoplasm of uncertain behavior of skin of nose D48.5

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Eustachian Tube

    a narrow passageway that connects the upper part of the throat to the tympanic cavity.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
antrum (Highmore) (maxillary)C31.0C78.39D02.3D14.0D38.5D49.1
antrum (Highmore) (maxillary) tympanicumC30.1C78.39D02.3D14.0D38.5D49.1
auditory canal (external) (skin) internalC30.1C78.39D02.3D14.0D38.5D49.1
auditory tubeC30.1C78.39D02.3D14.0D38.5D49.1
auricular canal (external) [See Also: Neoplasm, skin, ear] internalC30.1C78.39D02.3D14.0D38.5D49.2
cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] nose, nasalC30.0C78.39D02.3D14.0D38.5D49.1
cavity nasalC30.0C78.39D02.3D14.0D38.5D49.1
cavity tympanicC30.1C78.39D02.3D14.0D38.5D49.1
concha [See Also: Neoplasm, skin, ear] noseC30.0C78.39D02.3D14.0D38.5D49.1
ear (external) [See Also: Neoplasm, skin, ear] innerC30.1C78.39D02.3D14.0D38.5D49.1
ear (external) [See Also: Neoplasm, skin, ear] middleC30.1C78.39D02.3D14.0D38.5D49.1
ethmoid (sinus)C31.1C78.39D02.3D14.0D38.5D49.1
eustachian tubeC30.1C78.39D02.3D14.0D38.5D49.1
frontal sinusC31.2C78.39D02.3D14.0D38.5D49.1
mastoid (air cells) (antrum) (cavity)C30.1C78.39D02.3D14.0D38.5D49.1
maxilla, maxillary (superior) antrumC31.0C78.39D02.3D14.0D38.5D49.1
maxilla, maxillary (superior) sinusC31.0C78.39D02.3D14.0D38.5D49.1
mucosa nasalC30.0C78.39D02.3D14.0D38.5D49.1
nares, naris (anterior) (posterior)C30.0C78.39D02.3D14.0D38.5D49.1
nose, nasal cartilageC30.0C78.39D02.3D14.0D38.5D49.1
nose, nasal cavityC30.0C78.39D02.3D14.0D38.5D49.1
nose, nasal fossaC30.0C78.39D02.3D14.0D38.5D49.1
nose, nasal internalC30.0C78.39D02.3D14.0D38.5D49.1
nose, nasal mucosaC30.0C78.39D02.3D14.0D38.5D49.1
nose, nasal septumC30.0C78.39D02.3D14.0D38.5D49.1
nose, nasal turbinate (mucosa)C30.0C78.39D02.3D14.0D38.5D49.1
nose, nasal vestibuleC30.0C78.39D02.3D14.0D38.5D49.1
nostrilC30.0C78.39D02.3D14.0D38.5D49.1
respiratory tract NECC39.9C78.30D02.4D14.4D38.5D49.1
respiratory tract NEC upperC39.0C78.30D02.4D14.4D38.5D49.1
septumC30.0C78.39D02.3D14.0D38.5D49.1
septum nasalC30.0C78.39D02.3D14.0D38.5D49.1
sinus (accessory)C31.9C78.39D02.3D14.0D38.5D49.1
sinus (accessory) ethmoidalC31.1C78.39D02.3D14.0D38.5D49.1
sinus (accessory) frontalC31.2C78.39D02.3D14.0D38.5D49.1
sinus (accessory) maxillaryC31.0C78.39D02.3D14.0D38.5D49.1
sinus (accessory) nasal, paranasal NECC31.9C78.39D02.3D14.0D38.5D49.1
sinus (accessory) sphenoidC31.3C78.39D02.3D14.0D38.5D49.1
sphenoidC31.3C78.39D02.3D14.0D38.5D49.1
sphenoid sinusC31.3C78.39D02.3D14.0D38.5D49.1
turbinate (bone) nasalC30.0C78.39D02.3D14.0D38.5D49.1
tympanic cavityC30.1C78.39D02.3D14.0D38.5D49.1
vestibule noseC30.0C78.39D02.3D14.0D38.5D49.1

Patient EducationClinical

Lung Diseases

When you breathe, your lungs take in oxygen from the air and deliver it to the bloodstream. The cells in your body need oxygen to work and grow. During a normal day, you breathe nearly 25,000 times. People with lung disease have difficulty breathing. Millions of people in the U.S. have lung disease.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D38.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
235.9 Unc behav neo resp NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D38.5Overview

Is D38.5 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of uncertain behavior of other respiratory organs on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D38.5 group to?

When neoplasm of uncertain behavior of other respiratory organs is the principal diagnosis on an inpatient stay, it groups to MS-DRG 180, 181, 182, with relative weights from 0.7440 to 1.7660 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D38.5?

Under the General Equivalence Mappings, neoplasm of uncertain behavior of other respiratory organs converts to ICD-9-CM 235.9 (unc behav neo resp NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.