2026 ICD-10-CM Diagnosis Code C49.8Malignant neoplasm of overlapping sites of connective and soft tissue
ICD-10-CM Codes›C00–D49›C45-C49›C49
- Billable — Valid for Submission
- Chronic Condition
C49.8 is a billable ICD-10-CM diagnosis code for malignant neoplasm of overlapping sites of connective and soft tissue. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 542 through 544. Coders also document this condition as overlapping malignant neoplasm of soft tissues. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Sarcoma.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Overlapping malignant neoplasm of soft tissues
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Primary malignant neoplasm of two or more contiguous sites of connective and soft tissue
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Table of NeoplasmsClinical
Patient EducationClinical
Cancer
Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should.
The full article covers:
- What is cancer?
- What are the types of cancer?
- How does cancer develop?
- What are the symptoms of cancer?
- How is cancer diagnosed?
- What are the treatments for cancer?
- Can cancer be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert C49.8 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About C49.8Overview
Is C49.8 (Malignant neoplasm of other connective and soft tissue) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of overlapping sites of connective and soft tissue on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does C49.8 group to?
When malignant neoplasm of overlapping sites of connective and soft tissue is the principal diagnosis on an inpatient stay, it groups to MS-DRG 542, 543, 544, with relative weights from 0.7546 to 1.7665 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of C49.8?
Under the General Equivalence Mappings, malignant neoplasm of overlapping sites of connective and soft tissue converts to ICD-9-CM 171.8 (mal neo soft tissue NEC). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
