ICD-10-CM Code C49.9

Malignant neoplasm of connective and soft tissue, unspecified

Version 2020 Billable Code Neoplasm Malignant Primary

Valid for Submission

C49.9 is a billable code used to specify a medical diagnosis of malignant neoplasm of connective and soft tissue, unspecified. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code C49.9 might also be used to specify conditions or terms like adipocytic liposarcoma, alveolar rhabdomyosarcoma, alveolar soft part sarcoma, angiosarcoma, botryoid rhabdomyosarcoma, cutaneous fibrosarcoma, etc

The following anatomical sites found in the Table of Neoplasms apply to this code given the correct histological behavior: aponeurosis ; connective tissue NEC ; connective tissue NEC extremity ; connective tissue NEC limb NEC ; lymph, lymphatic channel NEC ; lymph, lymphatic channel NEC vessel [See Also: Neoplasm, connective tissue] ; etc

ICD-10:C49.9
Short Description:Malignant neoplasm of connective and soft tissue, unsp
Long Description:Malignant neoplasm of connective and soft tissue, unspecified

Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adipocytic liposarcoma
  • Alveolar rhabdomyosarcoma
  • Alveolar soft part sarcoma
  • Angiosarcoma
  • Botryoid rhabdomyosarcoma
  • Cutaneous fibrosarcoma
  • Cutaneous leiomyosarcoma
  • Cutaneous leiomyosarcoma with granular cell change
  • Dedifferentiated liposarcoma
  • Embryonal rhabdomyosarcoma
  • Epithelioid leiomyosarcoma of skin
  • Ewing's sarcoma of soft tissue
  • Extraskeletal osteosarcoma
  • Fibrosarcoma of connective tissue
  • Giant cell malignant fibrous histiocytoma of skin
  • Infantile fibrosarcoma
  • Inflammatory malignant fibrous histiocytoma of skin
  • Intergroup rhabdomyosarcoma study post-surgical clinical group IIIA: Localized or locally extensive tumor, gross residual disease after biopsy only
  • Intergroup rhabdomyosarcoma study post-surgical clinical group IIIB: Localized or locally extensive tumor, gross residual disease after major resection
  • Intergroup rhabdomyosarcoma study post-surgical clinical group IV: Any size primary tumor, with or without regional lymph node involvement, with distant metastases, without respect to surgical approach to primary tumor
  • Intravascular angiosarcoma
  • Leiomyosarcoma
  • Leiomyosarcoma of connective tissue
  • Liposarcoma
  • Liposarcoma of connective tissue
  • Local recurrence of malignant tumor of soft tissue
  • Low-grade fibromyxoid sarcoma
  • Lymphangiosarcoma
  • Malignant fibrohistiocytic tumor of skin
  • Malignant fibromatous neoplasm
  • Malignant fibrous histiocytoma
  • Malignant fibrous histiocytoma of skin
  • Malignant granular cell tumor
  • Malignant melanoma of soft tissues
  • Malignant neoplasm of bone, connective tissue, skin and breast
  • Malignant neoplasm of connective tissue
  • Malignant neoplasm of soft tissue
  • Malignant neoplasm of subcutaneous fibrous tissue
  • Malignant tumor of dermis
  • Malignant tumor of fibrous tissue
  • Malignant tumor of muscle
  • Metastasis from malignant tumor of soft tissues
  • Myxofibrosarcoma of skin
  • Myxoid leiomyosarcoma of skin
  • Myxoid liposarcoma
  • Pleomorphic liposarcoma
  • Pleomorphic malignant fibrous histiocytoma of skin
  • Pleomorphic rhabdomyosarcoma
  • Primary leiomyosarcoma
  • Primary liposarcoma of soft tissue of limb
  • Primary malignant neoplasm of blood vessel
  • Primary malignant neoplasm of muscle
  • Primary malignant neoplasm of soft tissues
  • Primary myxofibrosarcoma
  • Primary synovial sarcoma of soft tissue of limb
  • pT1a: Tumor 5 cm or less in greatest dimension, superficial tumor
  • pT1b: Tumor 5 cm or less in greatest dimension, deep tumor
  • pT2a: Tumor more than 5 cm in greatest dimension, superficial tumor
  • pT2b: Tumor more than 5 cm in greatest dimension, deep tumor
  • Rhabdomyosarcoma
  • Rhabdomyosarcoma of connective or soft tissue
  • Round cell liposarcoma
  • Sarcoma
  • Sarcoma of bone and connective tissue
  • Sarcoma of connective tissue
  • Sarcoma of soft tissue
  • Sclerosing liposarcoma
  • Soft tissue TNM finding
  • Soft tissue TNM finding
  • Soft tissue TNM finding
  • Soft tissue TNM finding
  • Spindle cell liposarcoma
  • Spindle cell rhabdomyosarcoma
  • Superficial malignant fibrous histiocytoma of skin
  • Surgical margin involved by sarcoma
  • Surgical margin involvement by sarcoma cannot be assessed
  • Surgical margin uninvolved by sarcoma
  • Synovial sarcoma
  • Synovial-like neoplasm
  • Vaccine-induced fibrosarcoma

Diagnostic Related Groups

The ICD-10 code C49.9 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2019 through 09/30/2020.

  • 542 - PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITH MCC
  • 543 - PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITH CC
  • 544 - PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITHOUT CC/MCC

Convert C49.9 to ICD-9

  • 171.9 - Mal neo soft tissue NOS (Approximate Flag)

Code Classification

  • Neoplasms (C00–D48)
    • Malignant neoplasms of mesothelial and soft tissue (C45-C49)
      • Malignant neoplasm of other connective and soft tissue (C49)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Table of Neoplasms

The code C49.9 is included in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»aponeurosis
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
  »extremity
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
  »limb NEC
C49.9C79.89D21.9D48.1D49.2
»lymph, lymphatic channel NEC
C49.9C79.89D21.9D48.1D49.2
»lymph, lymphatic channel NEC
  »vessel [See Also: Neoplasm, connective tissue]
C49.9C79.89D21.9D48.1D49.2

Information for Patients


Cancer

Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Most treatment plans may include surgery, radiation and/or chemotherapy. Some may involve hormone therapy, immunotherapy or other types of biologic therapy, or stem cell transplantation.

NIH: National Cancer Institute


[Learn More]

Connective Tissue Disorders

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.

Over 200 disorders that impact connective tissue. There are different types:

  • Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta
  • Autoimmune disorders, such as lupus and scleroderma
  • Cancers, like some types of soft tissue sarcoma

Each disorder has its own symptoms and needs different treatment.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


[Learn More]