2026 ICD-10-CM Diagnosis Code C49.6Malignant neoplasm of connective and soft tissue of trunk, unspecified

ICD-10-CM CodesC00–D49C45-C49C49

ICD-10-CM C49.6
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C49.6 is a billable ICD-10-CM diagnosis code for malignant neoplasm of connective and soft tissue of trunk, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 542 through 544. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Sarcoma.

Code Identity

ICD-10-CM Code
C49.6
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of connective and soft tissue of trunk, unspecified
Short Description
Malignant neoplasm of conn and soft tissue of trunk, unsp
Parent Code
Malignant neoplasm of other connective and soft tissue

Code Classification

ChapterC00–D49Neoplasms
SectionC45-C49Malignant neoplasms of mesothelial and soft tissue
CategoryC49Malignant neoplasm of other connective and soft tissue
This CodeC49.6Malignant neoplasm of connective and soft tissue of trunk, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Extrauterine adenocarcinoma
  • Malignant melanoma of trunk
  • Malignant neoplasm of soft tissue of back
  • Primary angiosarcoma of trunk
  • Primary leiomyosarcoma of trunk
  • Primary liposarcoma of soft tissue of trunk
  • Primary malignant neoplasm of blood vessel of trunk
  • Primary malignant neoplasm of muscle of trunk
  • Primary malignant neoplasm of soft tissues of trunk
  • Primary rhabdomyosarcoma of trunk
  • Primary sarcoma of trunk
  • Sarcoma of back

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Malignant neoplasm of back NOS

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO024
Sarcoma
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
connective tissue NEC backC49.6C79.89D21.6D48.1D49.2
connective tissue NEC flankC49.6C79.89D21.6D48.1D49.2
connective tissue NEC trunkC49.6C79.89D21.6D48.1D49.2

Patient EducationClinical

Cancer

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Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C49.6 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
171.7 Mal neopl trunk NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C49.6Overview

Is C49.6 (Malignant neoplasm of other connective and soft tissue) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of connective and soft tissue of trunk, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C49.6 group to?

When malignant neoplasm of connective and soft tissue of trunk, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 542, 543, 544, with relative weights from 0.7546 to 1.7665 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C49.6?

Under the General Equivalence Mappings, malignant neoplasm of connective and soft tissue of trunk, unspecified converts to ICD-9-CM 171.7 (mal neopl trunk NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.