2026 ICD-10-CM Diagnosis Code C49.5Malignant neoplasm of connective and soft tissue of pelvis

Billable — Valid for Submission
Chronic Condition

ICD-10-CM C49.5

CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C49.5 is a billable ICD-10-CM diagnosis code for malignant neoplasm of connective and soft tissue of pelvis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 542 through 544. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Sarcoma.

Code Identity

ICD-10-CM Code

C49.5

Billable Status

Yes — Valid for Submission

Code Describes

Malignant neoplasm of connective and soft tissue of pelvis

Short Description

Malignant neoplasm of connective and soft tissue of pelvis

Same as the full description in the CMS dataset.

Parent Code

C49

Malignant neoplasm of other connective and soft tissue

Code Classification

ChapterC00–D49Neoplasms

SectionC45-C49Malignant neoplasms of mesothelial and soft tissue

CategoryC49Malignant neoplasm of other connective and soft tissue

This CodeC49.5Malignant neoplasm of connective and soft tissue of pelvis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

Filter synonyms:

Malignant neoplasm of soft tissue of buttock
Malignant neoplasm of soft tissue of pelvis
Neoplasm of blood vessel of buttock
Neoplasm of blood vessel of inguinal region
Neoplasm of blood vessel of pelvis
Neoplasm of blood vessel of perineum
Neoplasm of coccygeal body
Neoplasm of muscle of buttock
Neoplasm of muscle of hip
Neoplasm of muscle of inguinal region
Neoplasm of muscle of pelvis
Neoplasm of muscle of perineum
Neoplasm of soft tissues of inguinal region
Primary angiosarcoma of inguinal region
Primary angiosarcoma of pelvis
Primary angiosarcoma of trunk
Primary leiomyosarcoma of buttock
Primary leiomyosarcoma of inguinal region
Primary leiomyosarcoma of pelvis
Primary leiomyosarcoma of perineum
Primary liposarcoma of soft tissue of buttock
Primary liposarcoma of soft tissue of inguinal region
Primary liposarcoma of soft tissue of limb
Primary liposarcoma of soft tissue of pelvis
Primary liposarcoma of soft tissue of perineum
Primary liposarcoma of soft tissue of trunk
Primary malignant fibrous histiocytoma of buttock
Primary malignant fibrous histiocytoma of soft tissue of lower limb
Primary malignant neoplasm of blood vessel of buttock
Primary malignant neoplasm of blood vessel of inguinal region
Primary malignant neoplasm of blood vessel of lower limb
Primary malignant neoplasm of blood vessel of pelvis
Primary malignant neoplasm of blood vessel of perineum
Primary malignant neoplasm of blood vessel of trunk
Primary malignant neoplasm of coccygeal body
Primary malignant neoplasm of inguinal region
Primary malignant neoplasm of muscle of buttock
Primary malignant neoplasm of muscle of hip
Primary malignant neoplasm of muscle of inguinal region
Primary malignant neoplasm of muscle of lower limb
Primary malignant neoplasm of muscle of pelvis
Primary malignant neoplasm of muscle of perineum
Primary malignant neoplasm of muscle of trunk
Primary malignant neoplasm of paraganglion
Primary malignant neoplasm of skin of perineum
Primary malignant neoplasm of soft tissues of buttock
Primary malignant neoplasm of soft tissues of inguinal region
Primary malignant neoplasm of soft tissues of pelvis
Primary malignant neoplasm of soft tissues of perineum
Primary rhabdomyosarcoma of buttock
Primary rhabdomyosarcoma of inguinal region
Primary rhabdomyosarcoma of pelvis
Primary rhabdomyosarcoma of perineum
Primary sarcoma of buttock
Primary sarcoma of inguinal region
Primary sarcoma of perineum
Sarcoma of pelvis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

Malignant neoplasm of buttock
Malignant neoplasm of groin
Malignant neoplasm of perineum

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO024

Sarcoma

Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

Filter table of neoplasms:

Site	Malig. Primary	Malig. Secondary	Ca in situ	Benign	Uncertain	Unspec.
coccygeal	C49.5	C79.89	–	D21.5	D48.1	D49.2
coccygeal › body or glomus	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › buttock	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › extrarectal	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › gluteal region	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › groin	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › iliopsoas muscle	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › inguinal (canal) (region)	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › ischiorectal fossa	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › nates	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › pararectal	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › para-urethral	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › paravaginal	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › pelvis (floor)	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › perineum	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › perirectal (tissue)	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › periurethral (tissue)	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › presacral	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › rectovaginal septum or wall	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › rectovesical	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › sacrococcygeal region	C49.5	C79.89	–	D21.5	D48.1	D49.2
connective tissue NEC › vesicorectal	C49.5	C79.89	–	D21.5	D48.1	D49.2
glomus	C49.5	C79.89	–	D21.5	D48.1	D49.2
glomus › coccygeal	C49.5	C79.89	–	D21.5	D48.1	D49.2

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Convert C49.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM

171.6 Mal neo soft tis pelvis

Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.

FY 2017–2025No changes

FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C49.5Overview

Is C49.5 (Malignant neoplasm of other connective and soft tissue) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of connective and soft tissue of pelvis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C49.5 group to?

When malignant neoplasm of connective and soft tissue of pelvis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 542, 543, 544, with relative weights from 0.7546 to 1.7665 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C49.5?

Under the General Equivalence Mappings, malignant neoplasm of connective and soft tissue of pelvis converts to ICD-9-CM 171.6 (mal neo soft tis pelvis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
The condition places limitations on self-care, independent living, and social interactions.

Indicator	Meaning	CMS pays CC/MCC DRG
Y	Diagnosis was present at the time of inpatient admission	Yes
N	Diagnosis was not present at the time of admission	No
U	Documentation is insufficient to determine	No
W	Clinically undetermined	Yes
1	Unreported, exempt from POA reporting	No