ICD-10-CM Excludes2 Notes · Chapter 2 · FY 2027 C00-D49

Excludes2 Notes in Chapter 2: Neoplasms ICD-10-CM

An Excludes2 note means "NOT INCLUDED HERE": the excluded condition is not part of this code, but a patient may have both, so both codes may be reported. In Chapter 2 (C00-D49), notes printed in the chapter name other codes 96 times, and Excludes2 Notes anywhere in the Tabular List name the chapter’s codes 116 times, covering 71 distinct codes, categories and ranges. Switch views to read the list either way.

✓ From the official FY 2027 ICD-10-CM Tabular ListDefinitions follow the Official Guidelines, Section I.A

References in Its Notes

116

References to Its Codes

Chapter Codes Named

C00-D49

Chapter 2

Excludes2 Notes by the code that carries the note

38 of 38 shown

C02.0 Malignant neoplasm of dorsal surface of tongue
- malignant neoplasm of dorsal surface of base of tongue (C01)
C02.4 Malignant neoplasm of lingual tonsil
- malignant neoplasm of tonsil NOS (C09.9)
C03 Malignant neoplasm of gum applies to 3 codes
- malignant odontogenic neoplasms (C41.0-C41.1)
C05.1 Malignant neoplasm of soft palate
- malignant neoplasm of nasopharyngeal surface of soft palate (C11.3)
C08 Malignant neoplasm of other and unspecified major salivary glands applies to 3 codes
- malignant neoplasms of minor salivary glands NOS (C06.9)
- malignant neoplasm of parotid gland (C07)
C09 Malignant neoplasm of tonsil applies to 4 codes
- malignant neoplasm of lingual tonsil (C02.4)
- malignant neoplasm of pharyngeal tonsil (C11.1)
C10 Malignant neoplasm of oropharynx applies to 7 codes
- malignant neoplasm of tonsil (C09.-)
C10.1 Malignant neoplasm of anterior surface of epiglottis
- malignant neoplasm of epiglottis (suprahyoid portion) NOS (C32.1)
C13 Malignant neoplasm of hypopharynx applies to 5 codes
- malignant neoplasm of pyriform sinus (C12)
C13.1 Malignant neoplasm of aryepiglottic fold, hypopharyngeal aspect
- malignant neoplasm of aryepiglottic fold or interarytenoid fold, laryngeal aspect (C32.1)
Block note Block C15-C26 Malignant neoplasms of digestive organs applies to 60 codes
- gastrointestinal stromal tumors (C49.A-)
C16 Malignant neoplasm of stomach applies to 9 codes
- malignant carcinoid tumor of the stomach (C7A.092)
C21 Malignant neoplasm of anus and anal canal applies to 4 codes
- malignant carcinoid tumors of the colon (C7A.02-)
- malignant melanoma of anal margin (C43.51)
- malignant melanoma of anal skin (C43.51)
- malignant melanoma of perianal skin (C43.51)
- other and unspecified malignant neoplasm of anal margin (C44.500, C44.510, C44.520, C44.590)
- other and unspecified malignant neoplasm of anal skin (C44.500, C44.510, C44.520, C44.590)
- other and unspecified malignant neoplasm of perianal skin (C44.500, C44.510, C44.520, C44.590)
C32.1 Malignant neoplasm of supraglottis
- malignant neoplasm of anterior surface of epiglottis (C10.1)
- malignant neoplasm of aryepiglottic fold or interarytenoid fold, hypopharyngeal aspect (C13.1)
- malignant neoplasm of aryepiglottic fold or interarytenoid fold, marginal zone (C13.1)
- malignant neoplasm of aryepiglottic fold or interarytenoid fold NOS (C13.1)
C41.0 Malignant neoplasm of bones of skull and face
- maxillary sinus (C31.0)
- upper jaw (C03.0)
- malignant neoplasm of jaw bone (lower) (C41.1)
C41.1 Malignant neoplasm of mandible
- jaw NOS (C03.9)
- lower (C03.1)
- malignant neoplasm of upper jaw bone (C41.0)
C43 Malignant melanoma of skin applies to 24 codes
- malignant melanoma of skin of genital organs (C51-C52, C60.-, C63.-)
- Merkel cell carcinoma (C4A.-)
C43.5 Malignant melanoma of trunk applies to 3 codes
- malignant neoplasm of anus NOS (C21.0)
- malignant neoplasm of scrotum (C63.2)
C46.1 Kaposi's sarcoma of soft tissue
- Kaposi's sarcoma of lymph glands and nodes (C46.3)
C49 Malignant neoplasm of other connective and soft tissue applies to 20 codes
- Kaposi's sarcoma of soft tissue (C46.1)
- malignant neoplasm of heart (C38.0)
- malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
- malignant neoplasm of peritoneum (C48.2)
- malignant neoplasm of retroperitoneum (C48.0)
- malignant neoplasm of uterine ligament (C57.3)
- mesothelioma (C45.-)
C4A.5 Merkel cell carcinoma of trunk applies to 3 codes
- malignant neoplasm of anus NOS (C21.0)
- malignant neoplasm of scrotum (C63.2)
C78 Secondary malignant neoplasm of respiratory and digestive organs applies to 15 codes
- lymph node metastases (C77.0)
C79.11 Secondary malignant neoplasm of bladder
- lymph node metastases (C77.0)
C7A Malignant neuroendocrine tumors applies to 23 codes
- malignant pancreatic islet cell tumors (C25.4)
- Merkel cell carcinoma (C4A.-)
Block note Block C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue applies to 533 codes
- Kaposi's sarcoma of lymph nodes (C46.3)
- secondary and unspecified neoplasm of lymph nodes (C77.-)
- secondary neoplasm of bone marrow (C79.52)
- secondary neoplasm of spleen (C78.89)
D04.0 Carcinoma in situ of skin of lip
- carcinoma in situ of vermilion border of lip (D00.01)
D12 Benign neoplasm of colon, rectum, anus and anal canal applies to 10 codes
- benign carcinoid tumors of the large intestine and rectum (D3A.02-)
- polyp of colon NOS (K63.5)
D12.6 Benign neoplasm of colon, unspecified
- inflammatory polyp of colon (K51.4-)
D16.4 Benign neoplasm of bones of skull and face
- benign neoplasm of lower jaw bone (D16.5)
D18 Hemangioma and lymphangioma, any site applies to 6 codes
- benign neoplasm of glomus jugulare (D35.6)
- blue or pigmented nevus (D22.-)
- nevus NOS (D22.-)
- vascular nevus (Q82.5)
D23 Other benign neoplasms of skin applies to 20 codes
- melanocytic nevi (D22.-)
D24 Benign neoplasm of breast applies to 3 codes
- adenofibrosis of breast (N60.2)
- benign cyst of breast (N60.-)
- benign mammary dysplasia (N60.-)
- benign neoplasm of skin of breast (D22.5, D23.5)
- fibrocystic disease of breast (N60.-)
D27 Benign neoplasm of ovary applies to 3 codes
- corpus albicans cyst (N83.2-)
- corpus luteum cyst (N83.1-)
- endometrial cyst (N80.1-)
- follicular (atretic) cyst (N83.0-)
- graafian follicle cyst (N83.0-)
- ovarian cyst NEC (N83.2-)
- ovarian retention cyst (N83.2-)
D3A Benign neuroendocrine tumors applies to 22 codes
- benign pancreatic islet cell tumors (D13.7)
D46 Myelodysplastic syndromes applies to 11 codes
- drug-induced aplastic anemia (D61.1)
D47.3 Essential (hemorrhagic) thrombocythemia
- reactive thrombocytosis (D75.838)
- secondary thrombocytosis (D75.838)
- thrombocythemia NOS (D75.839)
- thrombocytosis NOS (D75.839)
D47.Z2 Castleman disease
- Kaposi's sarcoma (C46.-)
D49 Neoplasms of unspecified behavior applies to 14 codes
- neoplasms of uncertain behavior (D37-D44, D48)

The first view lists notes printed in this chapter (a note on a category or block applies to every code beneath it). The second lists codes of this chapter named by Excludes2 Notes anywhere in the Tabular List, including notes in other chapters.

Questions About Excludes2 Notes

What does an Excludes2 note mean?

An Excludes2 note means “Not included here”: the excluded condition is not part of the condition represented by the code, but a patient may have both conditions at the same time (Section I.A.12.b). The FY 2027 Tabular List has 2,529 of them; 2,493 name other codes, with 2,799 references to 1,779 distinct codes, categories and ranges.

Can both codes be reported when there is an Excludes2 note?

Yes. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate: that is, when the patient has both conditions and both are documented.

Related References

ICD-10-CM Official Guidelines ICD-10-CM Code Lookup ICD-10-CM Codes List Code Lists by Tag

Source: FY 2027 ICD-10-CM Tabular List (CMS and NCHS) and the ICD-10-CM Official Guidelines for Coding and Reporting FY 2027, Section I.A. ICD List is not affiliated with CMS or NCHS.