2026 ICD-10-CM Diagnosis Code T81.12XSPostprocedural septic shock, sequela

ICD-10-CM Codes›S00–T88›T80-T88›T81

ICD-10-CM T81.12XS
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T81.12XS is a billable ICD-10-CM diagnosis code for postprocedural septic shock, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. Coders also document this condition as endotoxemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Complication, sequela.

Code Identity

ICD-10-CM Code
T81.12XS
Billable Status
Yes — Valid for Submission
Code Describes
Postprocedural septic shock, sequela
Short Description
Postprocedural septic shock, sequela
Same as the full description in the CMS dataset.
Parent Code
T81.12
Postprocedural septic shock

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT80-T88Complications of surgical and medical care, not elsewhere classified
CategoryT81Complications of procedures, not elsewhere classified
This CodeT81.12XSPostprocedural septic shock, sequela

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T81.12XS.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

T81.12XS is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Endotoxemia
  • Endotoxic shock
  • Endotoxicosis
  • Postoperative endotoxic shock
  • Postoperative septic shock
  • Postoperative shock

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Complications of procedures, not elsewhere classified (T81). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ076
Complication, sequela
Default principal diagnosis: inpatient No · outpatient Yes

Clinical InformationClinical

  • Endotoxemia

    a condition characterized by the presence of endotoxins in the blood. on lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

  • Endotoxins

    toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.

  • Postoperative Shock

    a state of shock following a surgical operation.

Convert T81.12XS to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.3 Late eff surg/med compl
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T81.12XSOverview

Is T81.12XS (Postprocedural septic shock) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report postprocedural septic shock, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character S in T81.12XS mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the postprocedural septic shock itself has resolved, not the original event.

What MS-DRG does T81.12XS group to?

On inpatient claims, postprocedural septic shock, sequela maps to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.

Can T81.12XS be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because postprocedural septic shock, sequela describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is T81.12XS exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for postprocedural septic shock, sequela on inpatient claims.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.