ICD-10-CM Tabular Index · Chapter 19 · FY 2027 T80

Complications following infusion, transfusion and therapeutic injection (T80) ICD-10-CM

The T80 code range covers complications following infusion, transfusion and therapeutic injection with 167 ICD-10-CM diagnosis codes. 114 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.

✓ Built from the official CMS FY 2027 datasetEffective Oct 1, 2026 – Sep 30, 2027
167
Diagnosis Codes
114
Billable Codes
T80
Code Range
T80–T88
Parent Section

Includes

This note appears immediately under a three character code title to further define, or give examples of, the content of the category.

Type 2 Excludes

A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

7th Character Note

Certain ICD-10-CM categories have applicable 7th characters. The applicable 7th character is required for all codes within the category, or as the notes in the Tabular List instruct. The 7th character must always be the 7th character in the data field. If a code that requires a 7th character is not 6 characters, a placeholder X must be used to fill in the empty characters.

7th Character

Indicates that a seventh character is to be assigned to codes in a subcategory.

ICD-10-CM

Codes in the T80 Range 167 codes · 114 billable

167 of 167 shown
  • T80 Complications following infusion, transfusion and therapeutic injectionNon-billable
  • T80.0 Air embolism following infusion, transfusion and therapeutic injectionNon-billable
  • T80.0XXA Air embolism following infusion, transfusion and therapeutic injection, initial encounter
  • T80.0XXD Air embolism following infusion, transfusion and therapeutic injection, subsequent encounter
  • T80.0XXS Air embolism following infusion, transfusion and therapeutic injection, sequela
  • T80.1 Vascular complications following infusion, transfusion and therapeutic injectionNon-billable
  • T80.1XXA Vascular complications following infusion, transfusion and therapeutic injection, initial encounter
  • T80.1XXD Vascular complications following infusion, transfusion and therapeutic injection, subsequent encounter
  • T80.1XXS Vascular complications following infusion, transfusion and therapeutic injection, sequela
  • T80.2 Infections following infusion, transfusion and therapeutic injectionNon-billable
  • T80.21 Infection due to central venous catheterNon-billable
  • T80.211 Bloodstream infection due to central venous catheterNon-billable
  • T80.211A Bloodstream infection due to central venous catheter, initial encounter
  • T80.211D Bloodstream infection due to central venous catheter, subsequent encounter
  • T80.211S Bloodstream infection due to central venous catheter, sequela
  • T80.212 Local infection due to central venous catheterNon-billable
  • T80.212A Local infection due to central venous catheter, initial encounter
  • T80.212D Local infection due to central venous catheter, subsequent encounter
  • T80.212S Local infection due to central venous catheter, sequela
  • T80.218 Other infection due to central venous catheterNon-billable
  • T80.218A Other infection due to central venous catheter, initial encounter
  • T80.218D Other infection due to central venous catheter, subsequent encounter
  • T80.218S Other infection due to central venous catheter, sequela
  • T80.219 Unspecified infection due to central venous catheterNon-billable
  • T80.219A Unspecified infection due to central venous catheter, initial encounter
  • T80.219D Unspecified infection due to central venous catheter, subsequent encounter
  • T80.219S Unspecified infection due to central venous catheter, sequela
  • T80.22 Acute infection following transfusion, infusion, or injection of blood and blood productsNon-billable
  • T80.22XA Acute infection following transfusion, infusion, or injection of blood and blood products, initial encounter
  • T80.22XD Acute infection following transfusion, infusion, or injection of blood and blood products, subsequent encounter
  • T80.22XS Acute infection following transfusion, infusion, or injection of blood and blood products, sequela
  • T80.29 Infection following other infusion, transfusion and therapeutic injectionNon-billable
  • T80.29XA Infection following other infusion, transfusion and therapeutic injection, initial encounter
  • T80.29XD Infection following other infusion, transfusion and therapeutic injection, subsequent encounter
  • T80.29XS Infection following other infusion, transfusion and therapeutic injection, sequela
  • T80.3 ABO incompatibility reaction due to transfusion of blood or blood productsNon-billable
  • T80.30 ABO incompatibility reaction due to transfusion of blood or blood products, unspecifiedNon-billable
  • T80.30XA ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
  • T80.30XD ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, subsequent encounter
  • T80.30XS ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela
  • T80.31 ABO incompatibility with hemolytic transfusion reactionNon-billable
  • T80.310 ABO incompatibility with acute hemolytic transfusion reactionNon-billable
  • T80.310A ABO incompatibility with acute hemolytic transfusion reaction, initial encounter
  • T80.310D ABO incompatibility with acute hemolytic transfusion reaction, subsequent encounter
  • T80.310S ABO incompatibility with acute hemolytic transfusion reaction, sequela
  • T80.311 ABO incompatibility with delayed hemolytic transfusion reactionNon-billable
  • T80.311A ABO incompatibility with delayed hemolytic transfusion reaction, initial encounter
  • T80.311D ABO incompatibility with delayed hemolytic transfusion reaction, subsequent encounter
  • T80.311S ABO incompatibility with delayed hemolytic transfusion reaction, sequela
  • T80.319 ABO incompatibility with hemolytic transfusion reaction, unspecifiedNon-billable
  • T80.319A ABO incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
  • T80.319D ABO incompatibility with hemolytic transfusion reaction, unspecified, subsequent encounter
  • T80.319S ABO incompatibility with hemolytic transfusion reaction, unspecified, sequela
  • T80.39 Other ABO incompatibility reaction due to transfusion of blood or blood productsNon-billable
  • T80.39XA Other ABO incompatibility reaction due to transfusion of blood or blood products, initial encounter
  • T80.39XD Other ABO incompatibility reaction due to transfusion of blood or blood products, subsequent encounter
  • T80.39XS Other ABO incompatibility reaction due to transfusion of blood or blood products, sequela
  • T80.4 Rh incompatibility reaction due to transfusion of blood or blood productsNon-billable
  • T80.40 Rh incompatibility reaction due to transfusion of blood or blood products, unspecifiedNon-billable
  • T80.40XA Rh incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
  • T80.40XD Rh incompatibility reaction due to transfusion of blood or blood products, unspecified, subsequent encounter
  • T80.40XS Rh incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela
  • T80.41 Rh incompatibility with hemolytic transfusion reactionNon-billable
  • T80.410 Rh incompatibility with acute hemolytic transfusion reactionNon-billable
  • T80.410A Rh incompatibility with acute hemolytic transfusion reaction, initial encounter
  • T80.410D Rh incompatibility with acute hemolytic transfusion reaction, subsequent encounter
  • T80.410S Rh incompatibility with acute hemolytic transfusion reaction, sequela
  • T80.411 Rh incompatibility with delayed hemolytic transfusion reactionNon-billable
  • T80.411A Rh incompatibility with delayed hemolytic transfusion reaction, initial encounter
  • T80.411D Rh incompatibility with delayed hemolytic transfusion reaction, subsequent encounter
  • T80.411S Rh incompatibility with delayed hemolytic transfusion reaction, sequela
  • T80.419 Rh incompatibility with hemolytic transfusion reaction, unspecifiedNon-billable
  • T80.419A Rh incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
  • T80.419D Rh incompatibility with hemolytic transfusion reaction, unspecified, subsequent encounter
  • T80.419S Rh incompatibility with hemolytic transfusion reaction, unspecified, sequela
  • T80.49 Other Rh incompatibility reaction due to transfusion of blood or blood productsNon-billable
  • T80.49XA Other Rh incompatibility reaction due to transfusion of blood or blood products, initial encounter
  • T80.49XD Other Rh incompatibility reaction due to transfusion of blood or blood products, subsequent encounter
  • T80.49XS Other Rh incompatibility reaction due to transfusion of blood or blood products, sequela
  • T80.5 Anaphylactic reaction due to serumNon-billable
  • T80.51 Anaphylactic reaction due to administration of blood and blood productsNon-billable
  • T80.51XA Anaphylactic reaction due to administration of blood and blood products, initial encounter
  • T80.51XD Anaphylactic reaction due to administration of blood and blood products, subsequent encounter
  • T80.51XS Anaphylactic reaction due to administration of blood and blood products, sequela
  • T80.52 Anaphylactic reaction due to vaccinationNon-billable
  • T80.52XA Anaphylactic reaction due to vaccination, initial encounter
  • T80.52XD Anaphylactic reaction due to vaccination, subsequent encounter
  • T80.52XS Anaphylactic reaction due to vaccination, sequela
  • T80.59 Anaphylactic reaction due to other serumNon-billable
  • T80.59XA Anaphylactic reaction due to other serum, initial encounter
  • T80.59XD Anaphylactic reaction due to other serum, subsequent encounter
  • T80.59XS Anaphylactic reaction due to other serum, sequela
  • T80.6 Other serum reactionsNon-billable
  • T80.61 Other serum reaction due to administration of blood and blood productsNon-billable
  • T80.61XA Other serum reaction due to administration of blood and blood products, initial encounter
  • T80.61XD Other serum reaction due to administration of blood and blood products, subsequent encounter
  • T80.61XS Other serum reaction due to administration of blood and blood products, sequela
  • T80.62 Other serum reaction due to vaccinationNon-billable
  • T80.62XA Other serum reaction due to vaccination, initial encounter
  • T80.62XD Other serum reaction due to vaccination, subsequent encounter
  • T80.62XS Other serum reaction due to vaccination, sequela
  • T80.69 Other serum reaction due to other serumNon-billable
  • T80.69XA Other serum reaction due to other serum, initial encounter
  • T80.69XD Other serum reaction due to other serum, subsequent encounter
  • T80.69XS Other serum reaction due to other serum, sequela
  • T80.8 Other complications following infusion, transfusion and therapeutic injectionNon-billable
  • T80.81 Extravasation of vesicant agentNon-billable
  • T80.810 Extravasation of vesicant antineoplastic chemotherapyNon-billable
  • T80.810A Extravasation of vesicant antineoplastic chemotherapy, initial encounter
  • T80.810D Extravasation of vesicant antineoplastic chemotherapy, subsequent encounter
  • T80.810S Extravasation of vesicant antineoplastic chemotherapy, sequela
  • T80.818 Extravasation of other vesicant agentNon-billable
  • T80.818A Extravasation of other vesicant agent, initial encounter
  • T80.818D Extravasation of other vesicant agent, subsequent encounter
  • T80.818S Extravasation of other vesicant agent, sequela
  • T80.82 Complication of immune effector cellular therapyNon-billable
  • T80.82XA Complication of immune effector cellular therapy, initial encounter
  • T80.82XD Complication of immune effector cellular therapy, subsequent encounter
  • T80.82XS Complication of immune effector cellular therapy, sequela
  • T80.89 Other complications following infusion, transfusion and therapeutic injectionNon-billable
  • T80.89XA Other complications following infusion, transfusion and therapeutic injection, initial encounter
  • T80.89XD Other complications following infusion, transfusion and therapeutic injection, subsequent encounter
  • T80.89XS Other complications following infusion, transfusion and therapeutic injection, sequela
  • T80.9 Unspecified complication following infusion, transfusion and therapeutic injectionNon-billable
  • T80.90 Unspecified complication following infusion and therapeutic injectionNon-billable
  • T80.90XA Unspecified complication following infusion and therapeutic injection, initial encounter
  • T80.90XD Unspecified complication following infusion and therapeutic injection, subsequent encounter
  • T80.90XS Unspecified complication following infusion and therapeutic injection, sequela
  • T80.91 Hemolytic transfusion reaction, unspecified incompatibilityNon-billable
  • T80.910 Acute hemolytic transfusion reaction, unspecified incompatibilityNon-billable
  • T80.910A Acute hemolytic transfusion reaction, unspecified incompatibility, initial encounter
  • T80.910D Acute hemolytic transfusion reaction, unspecified incompatibility, subsequent encounter
  • T80.910S Acute hemolytic transfusion reaction, unspecified incompatibility, sequela
  • T80.911 Delayed hemolytic transfusion reaction, unspecified incompatibilityNon-billable
  • T80.911A Delayed hemolytic transfusion reaction, unspecified incompatibility, initial encounter
  • T80.911D Delayed hemolytic transfusion reaction, unspecified incompatibility, subsequent encounter
  • T80.911S Delayed hemolytic transfusion reaction, unspecified incompatibility, sequela
  • T80.919 Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayedNon-billable
  • T80.919A Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed, initial encounter
  • T80.919D Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed, subsequent encounter
  • T80.919S Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed, sequela
  • T80.92 Unspecified transfusion reactionNon-billable
  • T80.92XA Unspecified transfusion reaction, initial encounter
  • T80.92XD Unspecified transfusion reaction, subsequent encounter
  • T80.92XS Unspecified transfusion reaction, sequela
  • T80.A Non-ABO incompatibility reaction due to transfusion of blood or blood productsNon-billable
  • T80.A0 Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecifiedNon-billable
  • T80.A0XA Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
  • T80.A0XD Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, subsequent encounter
  • T80.A0XS Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela
  • T80.A1 Non-ABO incompatibility with hemolytic transfusion reactionNon-billable
  • T80.A10 Non-ABO incompatibility with acute hemolytic transfusion reactionNon-billable
  • T80.A10A Non-ABO incompatibility with acute hemolytic transfusion reaction, initial encounter
  • T80.A10D Non-ABO incompatibility with acute hemolytic transfusion reaction, subsequent encounter
  • T80.A10S Non-ABO incompatibility with acute hemolytic transfusion reaction, sequela
  • T80.A11 Non-ABO incompatibility with delayed hemolytic transfusion reactionNon-billable
  • T80.A11A Non-ABO incompatibility with delayed hemolytic transfusion reaction, initial encounter
  • T80.A11D Non-ABO incompatibility with delayed hemolytic transfusion reaction, subsequent encounter
  • T80.A11S Non-ABO incompatibility with delayed hemolytic transfusion reaction, sequela
  • T80.A19 Non-ABO incompatibility with hemolytic transfusion reaction, unspecifiedNon-billable
  • T80.A19A Non-ABO incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
  • T80.A19D Non-ABO incompatibility with hemolytic transfusion reaction, unspecified, subsequent encounter
  • T80.A19S Non-ABO incompatibility with hemolytic transfusion reaction, unspecified, sequela
  • T80.A9 Other non-ABO incompatibility reaction due to transfusion of blood or blood productsNon-billable
  • T80.A9XA Other non-ABO incompatibility reaction due to transfusion of blood or blood products, initial encounter
  • T80.A9XD Other non-ABO incompatibility reaction due to transfusion of blood or blood products, subsequent encounter
  • T80.A9XS Other non-ABO incompatibility reaction due to transfusion of blood or blood products, sequela

Clinical Terms in This Code Range

Definitions from the National Library of Medicine for conditions coded in the T80 range.

Delayed Hemolytic Transfusion Reaction

Transfusion reaction complications such as delayed suppression of ERYTHROPOIESIS may occur after destruction of autologous RED BLOOD CELLS in Hemolytic Transfusion Reaction.

About the T80 Code Range

Infusions, transfusions and therapeutic injections can be followed by infections, blood-product reactions and other complications. T80 groups these complications by type.

T80.0 identifies air embolism, while T80.1 identifies vascular complications. Infection codes distinguish a central venous catheter, blood or blood products, and other infusions, transfusions or injections. Transfusion incompatibility reactions are separated into ABO, Rh and non-ABO types. Serum reaction codes distinguish blood products, vaccination and other serum; other codes identify complications such as extravasation of a vesicant agent.

The seventh character distinguishes an initial encounter, a subsequent encounter and a sequela, or later effect.

Questions About This Page

How many billable codes are in the T80 range?

Of the 167 codes in this range, 114 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.

What does the T80 range classify?

The range classifies complications following infusion, transfusion and therapeutic injection. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.

Related References

Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.