2021 ICD-10-CM Code R65.21
Severe sepsis with septic shock
Valid for Submission
R65.21 is a billable diagnosis code used to specify a medical diagnosis of severe sepsis with septic shock. The code R65.21 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions.
The ICD-10-CM code R65.21 might also be used to specify conditions or terms like endotoxemia, endotoxic shock, endotoxicosis, failed attempted termination of pregnancy complicated by shock, failed attempted termination of pregnancy with septic shock , hyperdynamic septic shock, etc.
The code R65.21 describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.
According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.
ICD-10: | R65.21 |
Short Description: | Severe sepsis with septic shock |
Long Description: | Severe sepsis with septic shock |
Code Classification
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code R65.21 are found in the index:
- - Infection, infected, infective (opportunistic) - B99.9
- - with
- - organ dysfunction (acute) - R65.20
- - with septic shock - R65.21
- - organ dysfunction (acute) - R65.20
- - with
- - Sepsis (generalized) (unspecified organism) - A41.9
- - with
- - organ dysfunction (acute) (multiple) - R65.20
- - with septic shock - R65.21
- - organ dysfunction (acute) (multiple) - R65.20
- - severe - R65.20
- - with septic shock - R65.21
- - with
- - Severe sepsis - R65.20
- - with septic shock - R65.21
- - Shock - R57.9
- - endotoxic - R65.21
- - gram-negative - R65.21
- - septic (due to severe sepsis) - R65.21
Code Edits
The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10 Code Edits are applicable to this code:
- Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Endotoxemia
- Endotoxic shock
- Endotoxicosis
- Failed attempted termination of pregnancy complicated by shock
- Failed attempted termination of pregnancy with septic shock
- Hyperdynamic septic shock
- Hypodynamic septic shock
- Illegal termination of pregnancy complicated by shock
- Illegal termination of pregnancy with septic shock
- Induced termination of pregnancy complicated by septic shock
- Induced termination of pregnancy complicated by shock
- Induced termination of pregnancy complicated by shock
- Infection after infusion
- Infection after transfusion
- Legal termination of pregnancy complicated by shock
- Legal termination of pregnancy with septic shock
- Miscarriage complicated by shock
- Miscarriage with septic shock
- Postprocedural septic shock
- Pyrogenic shock
- Septic shock
- Septic shock co-occurrent with acute organ dysfunction due to anaerobic bacteria
- Septic shock co-occurrent with acute organ dysfunction due to Chromobacterium
- Septic shock co-occurrent with acute organ dysfunction due to coagulase-negative Staphylococcus
- Septic shock co-occurrent with acute organ dysfunction due to Enterococcus
- Septic shock co-occurrent with acute organ dysfunction due to Gonococcus
- Septic shock co-occurrent with acute organ dysfunction due to Gram-positive coccus
- Septic shock co-occurrent with acute organ dysfunction due to Group A streptococcus
- Septic shock co-occurrent with acute organ dysfunction due to Group B streptococcus
- Septic shock co-occurrent with acute organ dysfunction due to Haemophilus influenzae
- Septic shock co-occurrent with acute organ dysfunction due to Meningococcus
- Septic shock co-occurrent with acute organ dysfunction due to methicillin resistant Staphylococcus aureus
- Septic shock co-occurrent with acute organ dysfunction due to methicillin susceptible Staphylococcus aureus
- Septic shock co-occurrent with acute organ dysfunction due to Pneumococcus
- Septic shock co-occurrent with acute organ dysfunction due to Pseudomonas
- Septic shock co-occurrent with acute organ dysfunction due to Serratia
- Septic shock co-occurrent with acute organ dysfunction due to Staphylococcus
- Septic shock co-occurrent with acute organ dysfunction due to Streptococcus
- Septic shock due to transfusion
- Septic shock following molar AND/OR ectopic pregnancy
- Severe sepsis with acute organ dysfunction due to Chromobacterium
- Shock following molar AND/OR ectopic pregnancy
Diagnostic Related Groups - MS-DRG Mapping
The ICD-10 code R65.21 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC). applicable from 10/01/2020 through 09/30/2021.
Convert R65.21 to ICD-9 Code
Information for Patients
Sepsis
Sepsis is a serious illness. It happens when your body has an overwhelming immune response to a bacterial infection. The chemicals released into the blood to fight the infection trigger widespread inflammation. This leads to blood clots and leaky blood vessels. They cause poor blood flow, which deprives your body's organs of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, blood pressure drops and the heart weakens, leading to septic shock.
Anyone can get sepsis, but the risk is higher in
- People with weakened immune systems
- Infants and children
- Adults 65 and older
- People with chronic illnesses, such as diabetes, AIDS, cancer, and kidney or liver disease
- People suffering from a severe burn or physical trauma
Common symptoms of sepsis are fever, chills, rapid breathing and heart rate, rash, confusion, and disorientation. Doctors diagnose sepsis using a blood test to see if the number of white blood cells is abnormal. They also do lab tests that check for signs of infection.
People with sepsis are usually treated in hospital intensive care units. Doctors try to treat the infection, sustain the vital organs, and prevent a drop in blood pressure. Many patients receive oxygen and intravenous (IV) fluids. Other types of treatment, such as respirators or kidney dialysis, may be necessary. Sometimes, surgery is needed to clear up an infection.
NIH: National Institute of General Medical Sciences
- Blood culture (Medical Encyclopedia)
- Group B streptococcal septicemia of the newborn (Medical Encyclopedia)
- Neonatal sepsis (Medical Encyclopedia)
- Sepsis (Medical Encyclopedia)
- Septic shock (Medical Encyclopedia)
- Septicemia (Medical Encyclopedia)
- Toxic shock syndrome (Medical Encyclopedia)
[Learn More]
Shock
Shock happens when not enough blood and oxygen can get to your organs and tissues. It causes very low blood pressure and may be life-threatening. It often happens along with a serious injury.
There are several kinds of shock. Hypovolemic shock happens when you lose a lot of blood or fluids. Causes include internal or external bleeding, dehydration, burns, and severe vomiting and/or diarrhea. Septic shock is caused by infections in the bloodstream. A severe allergic reaction can cause anaphylactic shock. An insect bite or sting might cause it. Cardiogenic shock happens when the heart cannot pump blood effectively. This may happen after a heart attack. Neurogenic shock is caused by damage to the nervous system.
Symptoms of shock include
- Confusion or lack of alertness
- Loss of consciousness
- Sudden and ongoing rapid heartbeat
- Sweating
- Pale skin
- A weak pulse
- Rapid breathing
- Decreased or no urine output
- Cool hands and feet
Shock is a life-threatening medical emergency and it is important to get help right away. Treatment of shock depends on the cause.
NIH: National Heart, Lung, and Blood Institute
- Anaphylaxis (Medical Encyclopedia)
- Cardiogenic shock (Medical Encyclopedia)
- Hypovolemic shock (Medical Encyclopedia)
- Septic shock (Medical Encyclopedia)
- Shock (Medical Encyclopedia)
[Learn More]
Code History
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)