2027 ICD-10-CM Diagnosis Code T80.89XSOther complications following infusion, transfusion and therapeutic injection, sequela
T80.89XS is a billable ICD-10-CM diagnosis code for other complications following infusion, transfusion and therapeutic injection, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Complication, sequela.
Code Identity
Code Classification
Present on Admission (POA)Billing
T80.89XS is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Complications of surgical and medical care, not elsewhere classified (T80-T88).
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Abdominal hernia as complication of peritoneal dialysis
- Acute disorder of hemodialysis
- Acute megaloblastic anemia
- Acute megaloblastic anemia due to dialysis
- Acute megaloblastic anemia secondary to total parenteral nutrition
- Adverse reaction following injection of substance
- Adynamic bone disease
- Air in infusion or transfusion due to mechanical failure of apparatus
- Allergic transfusion reaction
- Alloimmune platelet transfusion refractoriness
- Alloimmune thrombocytopenia
- Allosensitization
- Blister at injection site
- Bloodstained peritoneal dialysis effluent
- Chronic kidney disease mineral and bone disorder
- Chronic polyserositis
- Complication of hemodialysis
- Dialysis dementia
- Dialysis disequilibrium syndrome
- Dialysis fluid adverse reaction
- Dialysis-associated ascites
- Dialysis-associated hypoxia
- Encapsulating peritoneal sclerosis due to peritoneal dialysis
- Erythema at injection site
- Erythrocytosis due to autotransfusion
- Extravasation due to and following blood transfusion
- First use syndrome of dialysis
- Hematoma of dialysis access site
- Hemodialysis fluid adverse reaction
- Hemodialysis-associated pruritus
- Hemodialysis-associated pseudoporphyria
- Hemofiltration solution adverse reaction
- Hemolytic transfusion reaction
- Hemoperitoneum as complication of peritoneal dialysis
- Hemorrhage into peritoneal cavity
- Hemosiderosis
- Hydrothorax
- Hydrothorax as complication of peritoneal dialysis
- Hypercalcemia associated with chronic dialysis
- Hyperchloremic acidosis associated with dialysis
- Iatrogenic neonatal hyperglycemia
- Inadequate hemodialysis
- Inadequate peritoneal dialysis
- Infusion site swelling
- Injected limb mobility decreased
- Injection neuropathy
- Injection site anesthesia
- Injection site atrophy
- Injection site bruising
- Injection site burning
- Injection site cellulitis
- Injection site cyst
- Injection site dermatitis
- Injection site edema
- Injection site eruption
- Injection site fibrosis
- Injection site hemorrhage
- Injection site hypersensitivity
- Injection site indentation
- Injection site induration
- Injection site inflammation
- Injection site irritation
- Injection site itching
- Injection site malabsorption
- Injection site mass
- Injection site necrosis
- Injection site nerve damage
- Injection site pain
- Injection site paresthesia
- Injection site pigmentation change
- Injection site pruritus
- Injection site thrombosis
- Injection site urticaria
- Injection site warmth
- Injury due to and following infusion
- Injury due to and following therapeutic injection
- Injury due to and following transfusion
- Intestinal obstruction due to a procedure
- Introduction procedure site swelling
- Lipoatrophy caused by injected drug
- Lipogranuloma
- Localized lipoatrophy
- Long-term disorder of dialysis
- Loss of solute clearance
- Matrix stone formation during renal dialysis
- Mechanical failure of instrument or apparatus during infusion or transfusion
- Mechanical failure of instrument or apparatus during kidney dialysis
- Megaloblastic anemia due to hemodialysis
- Megaloblastic anemia due to hyperalimentation
- Meningitis due to and following intrathecal injection
- Meningitis following procedure
- Metabolic acidosis, NAG, acidifying salts
- Myelopathy post intrathecal injection of chemotherapeutic agent
- Neonatal hyperbilirubinemia following total parenteral nutrition
- Neonatal hyperglycemia
- Neonatal hyperglycemia due to iatrogenic intravenous therapy
- Neonatal polycythemia
- Non-allergic hypersensitivity reaction caused by dialysis membrane
- Non-allergic hypersensitivity reaction during dialysis
- Nontraumatic hemoperitoneum
- Osteonecrosis due to and following renal dialysis
- Pain during inflow of dialysate
- Pain during outflow of dialysate
- Penile sclerosing lipogranuloma
- Penile sclerosing lipogranuloma due to injection of substance
- Peritoneal dialysis solution adverse reaction
- Platelet alloimmunization
- Polycythemia neonatorum following blood transfusion
- Polyserositis
- Polyserositis syndrome of dialysis
- Porphyrin within reference range
- Post-dialysis dementia
- Pseudoporphyria
- Pulmonary transfusion reaction
- Reproductive system complication of procedure
- Sclerosing lipogranuloma
- Sclerosing peritonitis
- Sequelae of hyperalimentation
- Skin lesion associated with hemodialysis
- Swelling at injection site
- Thromboembolism following infusion, perfusion AND/OR transfusion
- Transfusion hemosiderosis
- Transfusion reaction caused by contaminant in blood
- Transfusion reaction caused by toxic effect of anticoagulant
- Transfusion reaction due to products of cell metabolism
- Ultrafiltration failure
- Underdialysis
- Urticarial transfusion reaction
Coding GuidelinesGuidance
The appropriate 7th character is to be added to each code from block Complications following infusion, transfusion and therapeutic injection (T80). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to T80.89XS: its own notes plus those printed at T80.89, T80, block T80-T88, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- complications following perfusion
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- bone marrow transplant rejection (T86.01)
- febrile nonhemolytic transfusion reaction (R50.84)
- fluid overload due to transfusion (E87.71)
- posttransfusion purpura (D69.51)
- transfusion associated circulatory overload (TACO) (E87.71)
- transfusion (red blood cell) associated hemochromatosis (E83.111)
- transfusion related acute lung injury (TRALI) (J95.84)
- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-)
- closure of external stoma (Z43.-)
- fitting and adjustment of external prosthetic device (Z44.-)
- burns and corrosions from local applications and irradiation (T20-T32)
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
- mechanical complication of respirator [ventilator] (J95.850)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- postprocedural fever (R50.82)
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0)
- colostomy malfunction (K94.0-)
- disorders of fluid and electrolyte imbalance (E86-E87)
- functional disturbances following cardiac surgery (I97.0-I97.1)
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- ostomy complications (J95.0-, K94.-, N99.5-)
- postgastric surgery syndromes (K91.1)
- postlaminectomy syndrome NEC (M96.1)
- postmastectomy lymphedema syndrome (I97.2)
- postsurgical blind-loop syndrome (K91.2)
- ventilator associated pneumonia (J95.851)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code to identify graft-versus-host reaction, if applicable, (D89.81-)
- code to identify any retained foreign body, if applicable (Z18.-)
Notes
General instructions on how these codes are used.
- Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
- The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.
7th Character
Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.
- The appropriate 7th character is to be added to each code from category T80
- Ainitial encounter
- Dsubsequent encounter
- Ssequela this code
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name T80.89XS, its category, or a range that includes it.
Excludes2 3
These codes carry an Excludes2 note naming T80.89XS: its condition is not part of those codes, and both may be reported when the patient has both.
- T45.8 Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agentstransfusion reactions (T80.-) names T80.-, which includes this code
- T81 Complications of procedures, not elsewhere classifiedcomplications following infusion, transfusion and therapeutic injection (T80.-) names T80.-, which includes this code
- T88 Other complications of surgical and medical care, not elsewhere classifiedcomplication following infusion, transfusion and therapeutic injection (T80.-) names T80.-, which includes this code
Code First 2
These codes say to code first a condition named in the note, and T80.89XS is one of the conditions named.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Convert T80.89XS to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T80.89XSOverview
Is T80.89XS a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other complications following infusion, transfusion and therapeutic injection, sequela on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What does the 7th character S in T80.89XS mean?
The final character S makes this a sequela code: it reports a lingering problem that remains after the other complications following infusion, transfusion and therapeutic injection itself has resolved, not the original event.
What MS-DRG does T80.89XS group to?
When other complications following infusion, transfusion and therapeutic injection, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 923, 922, with relative weights from 0.9980 to 1.6248 depending on complications. Higher weights mean higher Medicare reimbursement.
Is T80.89XS exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for other complications following infusion, transfusion and therapeutic injection, sequela on inpatient claims. The code appears in the Complications of surgical and medical care, not elsewhere classified (T80-T88) range of the CMS exempt list.
