D89.83 is a non-specific and non-billable ICD-10 code code, consider using a code with a higher level of specificity for a diagnosis of cytokine release syndrome. The code is not specific and is NOT valid for the year 2023 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
- Cytokine Release Syndrome-. a severe immune reaction characterized by excessive release of cytokines. symptoms include dyspnea; fever; headache; hypotension; nausea; rash; tachycardia; hypoxia; hyperferritinemia, and multiple organ failure. it is associated with viral infections, sepsis; autoimmune diseases and a variety of factors used in immunotherapy.
Specific Coding for Cytokine release syndrome
Non-specific codes like D89.83 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for cytokine release syndrome:
Tabular List of Diseases and Injuries
The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to this diagnosis code:
Code FirstCode First
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
- underlying cause, such as:
- complications following infusion, transfusion and therapeutic injection T80.89
- complications of transplanted organs and tissue T86
Use Additional CodeUse Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
- code to identify associated manifestations
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021