2027 ICD-10-CM Diagnosis Code T48.6X3SPoisoning by antiasthmatics, assault, sequela

ICD-10-CM Codes›S00–T88›T36-T50›T48

ICD-10-CM T48.6X3S
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T48.6X3S is a billable ICD-10-CM diagnosis code for poisoning by antiasthmatics, assault, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T48.6X3S
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by antiasthmatics, assault, sequela
Short Description
Poisoning by antiasthmatics, assault, sequela
Same as the full description in the CMS dataset.
Parent Code
Poisoning by antiasthmatics, assault

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT48Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system
This CodeT48.6X3SPoisoning by antiasthmatics, assault, sequela

Present on Admission (POA)Billing

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system (T48). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T48.6X3S: its own notes plus those printed at T48.6, T48, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From T48.6 Poisoning by, adverse effect of and underdosing of antiasthmatics, not elsewhere classified applies to 18 codes
  • poisoning by, adverse effect of and underdosing of beta-adrenoreceptor agonists not used in asthma therapy (T44.5)
  • poisoning by, adverse effect of and underdosing of anterior pituitary [adenohypophyseal] hormones (T38.8)
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T48 Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system applies to 180 codes
  • The appropriate 7th character is to be added to each code from category T48
  • Ainitial encounter
  • Dsubsequent encounter
  • Ssequela this code

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name T48.6X3S, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming T48.6X3S: they are not reported together with it, unless the two conditions are unrelated.

  • T44.5 Poisoning by, adverse effect of and underdosing of predominantly beta-adrenoreceptor agonists
    poisoning by, adverse effect of and underdosing of beta-adrenoreceptor agonists used in asthma therapy (T48.6-) names T48.6-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Acefylline piperazineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AcepifyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AlbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AmbuphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AminophyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AmlexanoxT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Antiasthmatic drug NECT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BambuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BamifyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BitolterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Bronchodilator NECT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BroxaterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BufrolinT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BufyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ButetamateT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
CarbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
CholineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Choline::theophyllinateT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ClenbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ClorprenalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Cromoglicic acidT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
CromolynT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
DoxantrazoleT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
EnprofyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
EtafedrineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
EtamiphyllinT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Ethyl::noradrenalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Ethylenediamine theophyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
EthylnorepinephrineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
FenoterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
FlunisolideT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Flutropium bromideT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Folium stramoniaeT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
GlyphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
HexoprenalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
IbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Ipratropium (bromide)T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
IsoetarineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
IsoprenalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
IsoproterenolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
LevalbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
LevoproxyphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
MethoxyphenamineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
NedocromilT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Oxitropium bromideT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
OxtriphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Pemirolast (potassium)T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
PirbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ProtokylolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ProxyphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ReproterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Respiratory drug NEC::antiasthmatic NECT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
RimiterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
SalbutamolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
SalmeterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Sodium::cromoglicateT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Spasmolytic::bronchial NECT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
StramoniumT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Sympathomimetic NEC::bronchodilatorT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TerbutalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theobromine (calcium salicylate)T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theobromine (calcium salicylate)::sodium salicylateT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TheophyllamineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TheophyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theophylline::aminobenzoic acidT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theophylline::ethylenediamineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theophylline::piperazine p-amino-benzoateT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TretoquinolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TulobuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T48.6X3S to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.0 Late eff drug poisoning
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E969 Late effect assault
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T48.6X3SOverview

What is the ICD-10 code for poisoning by antiasthmatics, assault, sequela?

The ICD-10-CM code for poisoning by antiasthmatics, assault, sequela is T48.6X3S (sometimes written as T486X3S). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is T48.6X3S (Poisoning by antiasthmatics, assault) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by antiasthmatics, assault, sequela on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character S in T48.6X3S mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the poisoning by antiasthmatics, assault itself has resolved, not the original event.

What MS-DRG does T48.6X3S group to?

When poisoning by antiasthmatics, assault, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 923, 922, with relative weights from 0.9980 to 1.6248 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T48.6X3S exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for poisoning by antiasthmatics, assault, sequela on inpatient claims. The code appears in the Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50) range of the CMS exempt list.