2021 ICD-10-CM Code T48.6X5

Adverse effect of antiasthmatics

Version 2021
Replaced Code
Non-Billable Code
Adverse Effect

Not Valid for Submission

T48.6X5 is a "header" nonspecific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of antiasthmatics. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

The ICD-10-CM code T48.6X5 might also be used to specify conditions or terms like adverse reaction to antiasthmatic, adverse reaction to purine derivative diuretic, adverse reaction to purine derivative diuretic, adverse reaction to theobromine, aminophylline adverse reaction , bambuterol adverse reaction, etc.

ICD-10:T48.6X5
Short Description:Adverse effect of antiasthmatics
Long Description:Adverse effect of antiasthmatics

Code Classification

Specific Coding for Adverse effect of antiasthmatics

Header codes like T48.6X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for adverse effect of antiasthmatics:

Replaced Code

This code was replaced in the 2021 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2020. This code was replaced for the FY 2021 (October 1, 2020 - September 30, 2021).


  • K59.03 - Drug induced constipation

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Table of Drugs and Chemicals

The code T48.6X5 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. According to ICD-10 coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
Acefylline piperazineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AcepifyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AlbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AmbuphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AminophyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
AmlexanoxT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Antiasthmatic drug NECT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BambuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BamifyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BitolterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Bronchodilator NECT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BroxaterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BufrolinT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
BufyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ButetamateT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
CarbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
CholineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Choline
  »chloride
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Choline
  »dihydrogen citrate
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Choline
  »salicylate
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Choline
  »theophyllinate
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ClenbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ClorprenalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Cromoglicic acidT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
CromolynT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
DoxantrazoleT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
EnprofyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
EtafedrineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
EtamiphyllinT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Ethylenediamine theophyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
EthylnorepinephrineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
FenoterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
FlunisolideT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Flutropium bromideT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Folium stramoniaeT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
GlyphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
HexoprenalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
IbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Ipratropium (bromide)T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
IsoetarineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
IsoprenalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
IsoproterenolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
LevalbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
LevoproxyphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
MethoxyphenamineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
NedocromilT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Oxitropium bromideT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
OxtriphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Pemirolast (potassium)T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
PirbuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ProtokylolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ProxyphyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
ReproterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
RimiterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
SalbutamolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
SalmeterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
StramoniumT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Stramonium
  »natural state
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TerbutalineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theobromine (calcium salicylate)T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theobromine (calcium salicylate)
  »sodium salicylate
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TheophyllamineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TheophyllineT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theophylline
  »aminobenzoic acid
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theophylline
  »ethylenediamine
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
Theophylline
  »piperazine p-amino-benzoate
T48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TretoquinolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6
TulobuterolT48.6X1T48.6X2T48.6X3T48.6X4T48.6X5T48.6X6

Information for Patients


Drug Reactions

Also called: Side effects

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.


[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)