2027 ICD-10-CM Diagnosis Code R87.621Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H)
ICD-10-CM Codes›R00–R99›R83-R89›R87
- Billable — Valid for Submission
- Not Chronic
R87.621 is a billable ICD-10-CM diagnosis code for atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H). It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 742 through 743, 760 through 761. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as abnormal vaginal Papanicolaou smear. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.
This medical diagnosis code is frequently used in OB/GYN medical specialties to designate conditions such abnormal female genital cytology.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Abnormal vaginal Papanicolaou smear
- Atypical squamous cells on vaginal Papanicolaou smear cannot exclude high grade squamous intraepithelial lesion
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to R87.621: its own notes plus those printed at R87.62, R87, block R83-R89, and Chapter 18. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- abnormal findings in secretion and smears from cervix uteri
- abnormal findings in secretion and smears from vagina
- abnormal findings in secretion and smears from vulva
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- abnormal cytological findings in specimens from cervix uteri (R87.61-)
- abnormal cytological findings in specimens from other female genital organs (R87.69)
- carcinoma in situ of vagina (histologically confirmed) (D07.2)
- vaginal intraepithelial neoplasia I [VAIN I] (N89.0)
- vaginal intraepithelial neoplasia II [VAIN II] (N89.1)
- vaginal intraepithelial neoplasia III [VAIN III] (D07.2)
- dysplasia (mild) (moderate) of vagina (histologically confirmed) (N89.-)
- severe dysplasia of vagina (histologically confirmed) (D07.2)
- abnormal findings on antenatal screening of mother (O28.-)
- diagnostic abnormal findings classified elsewhere - see Alphabetical Index
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Use Additional Code
Add a second code, after this one, to fully describe the condition.
Notes
General instructions on how these codes are used.
- This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
- Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
- The conditions and signs or symptoms included in categories R00-R94 consist of:
- (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
- (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
- (c) provisional diagnosis in a patient who failed to return for further investigation or care;
- (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
- (e) cases in which a more precise diagnosis was not available for any other reason;
- (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name R87.621, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming R87.621: they are not reported together with it, unless the two conditions are unrelated.
- N89 Other noninflammatory disorders of vaginaabnormal results from vaginal cytologic examination without histologic confirmation (R87.62-) names R87.62-, which includes this code
- R87.61 Abnormal cytological findings in specimens from cervix uteriabnormal cytological findings in specimens from vagina (R87.62-) names R87.62-, which includes this code
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Abnormal, abnormality, abnormalities See Also: Anomaly;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Convert R87.621 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About R87.621Overview
Is R87.621 (Abnormal cytological findings in specimens from vagina) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H) on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does R87.621 group to?
When atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H) is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.7039 to 1.8448 depending on complications. Higher weights mean higher Medicare reimbursement.
Can R87.621 be a principal diagnosis?
Use it with care. This is a symptom code, so once a definitive diagnosis explaining the atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H) is established, that condition takes the principal position instead.
Can R87.621 be reported with a code from R87.61?
Not as a rule. The Excludes1 note at R87.62, which applies to R87.621, lists "abnormal cytological findings in specimens from cervix uteri (R87.61-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
