2027 ICD-10-CM Diagnosis Code R76.0Raised antibody titer

ICD-10-CM Codes›R00–R99›R70-R79›R76

ICD-10-CM R76.0
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

R76.0 is a billable ICD-10-CM diagnosis code for raised antibody titer. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 814 through 816. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.

Code Identity

ICD-10-CM Code
R76.0
Billable Status
Yes — Valid for Submission
Code Describes
Raised antibody titer
Short Description
Raised antibody titer
Same as the full description in the CMS dataset.
Parent Code
R76
Other abnormal immunological findings in serum

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR70-R79Abnormal findings on examination of blood, without diagnosis
CategoryR76Other abnormal immunological findings in serum
This CodeR76.0Raised antibody titer

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal blood test
  • Anti-citrullinated protein antibody detected
  • Anti-citrullinated protein antibody positive arthralgia
  • Antistreptolysin O titer above reference range
  • Anti-streptolysin titer outside reference range
  • Autoantibody titer detected
  • Bacterial antibody detected
  • Basement membrane antibodies detected
  • Cyclic citrullinated peptide antibody measurement above reference range
  • Finding of Rubella virus antibody titer
  • Fourfold or greater increase in specific IgG titer
  • High antibody titer
  • Parietal cell antibodies detected
  • Parietal cell antibodies weakly detected
  • Raised antinuclear antibody
  • Raised Helicobacter pylori antibody
  • Rheumatoid factor detected
  • Rubella virus antibody - rising titer
  • Toxoplasma gondii antibody detected
  • Toxoplasma titer above reference range
  • Viral antibody titer - finding

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to R76.0: its own notes plus those printed at block R70-R79 and Chapter 18. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

  • isoimmunization in pregnancy (O36.0-O36.1)
  • isoimmunization affecting newborn (P55.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block R70-R79 Abnormal findings on examination of blood, without diagnosis applies to 45 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • abnormalities of lipids (E78.-)
  • abnormalities of platelets and thrombocytes (D69.-)
  • abnormalities of white blood cells classified elsewhere (D70-D72)
  • coagulation hemorrhagic disorders (D65-D68)
  • diagnostic abnormal findings classified elsewhere - see Alphabetical Index
  • hemorrhagic and hematological disorders of newborn (P50-P61)
From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

Notes

General instructions on how these codes are used.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • The conditions and signs or symptoms included in categories R00-R94 consist of:
  • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • (e) cases in which a more precise diagnosis was not available for any other reason;
  • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name R76.0, its category, or a range that includes it.

Excludes1 6

These codes carry an Excludes1 note naming R76.0: they are not reported together with it, unless the two conditions are unrelated.

  • D68.312 Antiphospholipid antibody with hemorrhagic disorder
    antiphospholipid antibody, finding without diagnosis (R76.0)
  • D68.312 Antiphospholipid antibody with hemorrhagic disorder
    lupus anticoagulant (LAC) finding without diagnosis (R76.0)
  • D68.312 Antiphospholipid antibody with hemorrhagic disorder
    systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
  • D68.5 Primary thrombophilia
    systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
  • D68.61 Antiphospholipid syndrome
    anti-phospholipid antibody, finding without diagnosis (R76.0)
  • D68.62 Lupus anticoagulant syndrome
    lupus anticoagulant (LAC) finding without diagnosis (R76.0)

Excludes2 1

These codes carry an Excludes2 note naming R76.0: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
    abnormal findings on examination of blood, without diagnosis (R70-R79) names R70-R79, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM017
Abnormal findings without diagnosis
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Immune System and Disorders

Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.

The full article covers:

  • What is the immune system?
  • What are the parts of the immune system?
  • How does the immune system work?
  • What are the types of immunity?
  • What can go wrong with the immune system?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert R76.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
795.79 Oth unspcf nspf imun fnd
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About R76.0Overview

What is the ICD-10 code for raised antibody titer?

The ICD-10-CM code for raised antibody titer is R76.0 (sometimes written as R760). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is R76.0 (Other abnormal immunological findings in serum) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report raised antibody titer on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does R76.0 group to?

When raised antibody titer is the principal diagnosis on an inpatient stay, it groups to MS-DRG 816, 814, 815, with relative weights from 0.7378 to 2.0727 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R76.0 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the raised antibody titer is established, that condition takes the principal position instead.

Can R76.0 be reported with a code from P55?

Not as a rule. The Excludes1 note on R76.0 lists "isoimmunization affecting newborn (P55.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).