2027 ICD-10-CM Diagnosis Code R75Inconclusive laboratory evidence of human immunodeficiency virus [HIV]

ICD-10-CM Codes›R00–R99›R70-R79›R75

ICD-10-CM R75
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

R75 is a billable ICD-10-CM diagnosis code for inconclusive laboratory evidence of human immunodeficiency virus [HIV]. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 814 through 816. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as human immunodeficiency virus p24 antigen detected. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.

Code Identity

ICD-10-CM Code
R75
Billable Status
Yes — Valid for Submission
Code Describes
Inconclusive laboratory evidence of human immunodeficiency virus [HIV]
Short Description
Inconclusive laboratory evidence of human immunodef virus
Chapter
R70-R79
Abnormal findings on examination of blood, without diagnosis

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR70-R79Abnormal findings on examination of blood, without diagnosis
CategoryR75Inconclusive laboratory evidence of human immunodeficiency virus [HIV]
This CodeR75Inconclusive laboratory evidence of human immunodeficiency virus [HIV]

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Human immunodeficiency virus p24 antigen detected
  • Reactive for both human immunodeficiency virus antibodies and p24 antigen

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to R75: its own notes plus those printed at block R70-R79 and Chapter 18. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Nonconclusive HIV-test finding in infants

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

  • asymptomatic human immunodeficiency virus [HIV] infection status (Z21)
  • human immunodeficiency virus [HIV] disease (B20)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block R70-R79 Abnormal findings on examination of blood, without diagnosis applies to 45 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • abnormalities of lipids (E78.-)
  • abnormalities of platelets and thrombocytes (D69.-)
  • abnormalities of white blood cells classified elsewhere (D70-D72)
  • coagulation hemorrhagic disorders (D65-D68)
  • diagnostic abnormal findings classified elsewhere - see Alphabetical Index
  • hemorrhagic and hematological disorders of newborn (P50-P61)
From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

Notes

General instructions on how these codes are used.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • The conditions and signs or symptoms included in categories R00-R94 consist of:
  • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • (e) cases in which a more precise diagnosis was not available for any other reason;
  • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name R75, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming R75: they are not reported together with it, unless the two conditions are unrelated.

  • B20 Human immunodeficiency virus [HIV] disease
    inconclusive serologic evidence of HIV (R75)
  • Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
    inconclusive laboratory evidence of human immunodeficiency virus [HIV] (R75)

Excludes2 3

These codes carry an Excludes2 note naming R75: its condition is not part of those codes, and both may be reported when the patient has both.

  • P09 Abnormal findings on neonatal screening
    nonspecific serologic evidence of human immunodeficiency virus [HIV] (R75)
  • Block P35-P39 Infections specific to the perinatal period
    laboratory evidence of human immunodeficiency virus [HIV] (R75)
  • Block R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
    abnormal findings on examination of blood, without diagnosis (R70-R79) names R70-R79, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM017
Abnormal findings without diagnosis
Default principal diagnosis: inpatient Yes · outpatient Yes

Convert R75 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
795.71 Nonspcf serlgc evdnc hiv
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About R75Overview

What is the ICD-10 code for inconclusive laboratory evidence of human immunodeficiency virus [HIV]?

The ICD-10-CM code for inconclusive laboratory evidence of human immunodeficiency virus [HIV] is R75. It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is R75 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report inconclusive laboratory evidence of human immunodeficiency virus [HIV] on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does R75 group to?

When inconclusive laboratory evidence of human immunodeficiency virus [HIV] is the principal diagnosis on an inpatient stay, it groups to MS-DRG 816, 814, 815, with relative weights from 0.7378 to 2.0727 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R75 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the inconclusive laboratory evidence of human immunodeficiency virus [HIV] is established, that condition takes the principal position instead.

Can R75 be reported with Z21?

Not as a rule. The Excludes1 note on R75 lists "asymptomatic human immunodeficiency virus [HIV] infection status (Z21)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).