Other abnormalities of plasma proteins (R77) ICD-10-CM
The R77 code range covers other abnormalities of plasma proteins with 6 ICD-10-CM diagnosis codes. 5 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- disorders of plasma-protein metabolism E88.0
Codes in the R77 Range 6 codes · 5 billable
About the R77 Code Range
The ICD-10 code R77 covers various unusual findings related to plasma proteins in the blood. These codes help identify specific abnormalities of proteins such as albumin, globulin, and alphafetoprotein when test results fall outside normal ranges but do not yet point to a definite diagnosis.
The section includes detailed codes: R77.0 is used for abnormalities in albumin levels or structure, often referred to by terms like "serum albumin above or below reference range" and "thyroxine transport defect." R77.1 addresses globulin irregularities, covering conditions described as "hyperglobulinemia" or "hypoglobulinemia," with various alpha and beta globulin level deviations. R77.2 is specific to abnormal alphafetoprotein measurements, including elevated or deficient levels noted as "serum alpha-fetoprotein level." Other abnormalities not classified elsewhere fall under R77.8, which includes issues like high fibrinogen or ferritin levels. When a plasma protein abnormality is detected but not specified, R77.9 applies. Understanding these codes aids clinicians and coders in accurately capturing blood protein test irregularities for patient records and further evaluation.
Questions About This Page
How many billable codes are in the R77 range?
Of the 6 codes in this range, 5 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the R77 range classify?
The range classifies other abnormalities of plasma proteins. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
