2027 ICD-10-CM Diagnosis Code Q78.2Osteopetrosis
ICD-10-CM Codes›Q00-Q99›Q65-Q79›Q78
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- POA Exempt
- Chronic Condition
Q78.2 is a billable ICD-10-CM diagnosis code for osteopetrosis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 564 through 566. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 10 closely related codes. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Musculoskeletal congenital conditions.
Code Identity
Code Classification
Present on Admission (POA)Billing
Q78.2 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Congenital malformations and deformations of the musculoskeletal system (Q65-Q79).
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Anhidrotic ectodermal dysplasia, immunodeficiency, osteopetrosis, lymphedema syndrome
- Autosomal dominant osteopetrosis type 1
- Autosomal dominant osteopetrosis type 2
- Colobomatous microphthalmia
- COMMAD syndrome
- Complete deafness
- Congenital deafness
- Congenital hypogammaglobulinemia
- Dentin dysplasia
- Dentin dysplasia with sclerotic bone syndrome
- Endosteal hyperostoses
- Hypogammaglobulinemia
- Infantile malignant osteopetrosis
- Infantile osteopetrosis with neuroaxonal dysplasia syndrome
- Lenz-Majewski hyperostosis syndrome
- Osteochondrodysplasia with osteopetrosis
- Osteomesopyknosis
- Osteopathia striata
- Osteopathia striata with cranial sclerosis
- Osteopetrosis
- Osteopetrosis - delayed type
- Osteopetrosis - intermediate type
- Osteopetrosis hypogammaglobulinemia syndrome
- Osteopetrosis with renal tubular acidosis
- Osteosclerosis
- Osteosclerosis - Stanescu type
- Osteosclerosis, developmental delay, craniosynostosis syndrome
- Osteosclerotic metaphyseal dysplasia
- Pathologic fracture of right foot due to osteopetrosis
- Pathological fracture of foot due to osteopetrosis
- Pathological fracture of left foot
- Pathological fracture of left foot due to osteopetrosis
- Pathological fracture of right foot
- Progressive macrocephaly
- Sclerosis of craniofacial bone
- Sclerosteosis
- Short stature disorder due to osteosclerosis
- Specific antibody deficiency
- Transient infantile osteopetrosis
- Worth disease
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to Q78.2: its own notes plus those printed at Q78 and Chapter 17. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Albers-Schönberg syndrome
- Osteosclerosis NOS
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- congenital myotonic chondrodystrophy (G71.13)
Notes
General instructions on how these codes are used.
- Codes from this chapter are not for use on maternal records
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name Q78.2, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming Q78.2: they are not reported together with it, unless the two conditions are unrelated.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disease, diseased See Also: Syndrome;
Ivory bones Q78.2
Osteopetrosis (familial) Q78.2
Osteosclerosis Q78.2
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Osteopetrosis
excessive formation of dense trabecular bone leading to pathological fractures; osteitis; splenomegaly with infarct; anemia; and extramedullary hemopoiesis (hematopoiesis, extramedullary).
Patient EducationClinical
Birth Defects
A birth defect is a problem that happens while a baby is developing in the mother's body. Most birth defects happen during the first 3 months of pregnancy. One out of every 33 babies in the United States is born with a birth defect.
The full article covers:
- What are birth defects?
- What causes birth defects?
- Who is at risk of having a baby with birth defects?
- How are birth defects diagnosed?
- What are the treatments for birth defects?
- Can birth defects be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Q78.2 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Q78.2Overview
What is the ICD-10 code for osteopetrosis?
The ICD-10-CM code for osteopetrosis is Q78.2 (sometimes written as Q782). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is Q78.2 (Other osteochondrodysplasias) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report osteopetrosis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does Q78.2 group to?
When osteopetrosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 566, 565, with relative weights from 0.7374 to 1.4909 depending on complications. Higher weights mean higher Medicare reimbursement.
Is Q78.2 a CC or MCC?
CMS lists Q78.2 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 10 closely related codes in its exclusion list.
Is Q78.2 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for osteopetrosis on inpatient claims. The code appears in the Congenital malformations and deformations of the musculoskeletal system (Q65-Q79) range of the CMS exempt list.
