2027 ICD-10-CM Diagnosis Code Q78.0Osteogenesis imperfecta
ICD-10-CM Codes›Q00-Q99›Q65-Q79›Q78
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- POA Exempt
- Chronic Condition
Q78.0 is a billable ICD-10-CM diagnosis code for osteogenesis imperfecta. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 456 through 458, 564 through 566. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 10 closely related codes. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Musculoskeletal congenital conditions.
Code Identity
Code Classification
Present on Admission (POA)Billing
Q78.0 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Congenital malformations and deformations of the musculoskeletal system (Q65-Q79).
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Abnormal blue sclerae
- Congenital anomaly of sclera
- Dentinogenesis imperfecta
- Doughnut lesion of calvaria and bone fragility syndrome
- Ehlers-Danlos and osteogenesis imperfecta syndrome
- Grange syndrome
- Hereditary dysplasia of blood vessel
- High bone mass osteogenesis imperfecta
- Osteogenesis imperfecta
- Osteogenesis imperfecta type 5
- Osteogenesis imperfecta type I
- Osteogenesis imperfecta type IIA
- Osteogenesis imperfecta type IIB
- Osteogenesis imperfecta type IIC
- Osteogenesis imperfecta type III
- Osteogenesis imperfecta with blue sclerae AND dentinogenesis imperfecta
- Osteogenesis imperfecta with blue sclerae AND normal teeth
- Osteogenesis imperfecta with normal sclerae, dominant form
- Osteogenesis imperfecta, dominant perinatal lethal
- Osteogenesis imperfecta, perinatal lethal
- Osteogenesis imperfecta, recessive perinatal lethal
- Osteogenesis imperfecta, recessive perinatal lethal, with microcephaly AND cataracts
- Osteogenesis imperfecta, retinopathy, seizures, intellectual disability syndrome
- Osteogenesis imperfecta, type IV A
- Osteogenesis imperfecta, type IV B
- Osteoporosis with pseudoglioma
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to Q78.0: its own notes plus those printed at Q78 and Chapter 17. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Fragilitas ossium
- Osteopsathyrosis
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- congenital myotonic chondrodystrophy (G71.13)
Notes
General instructions on how these codes are used.
- Codes from this chapter are not for use on maternal records
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name Q78.0, its category, or a range that includes it.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
bones disease Q78.0
Disease, diseased See Also: Syndrome;
Osteitis See Also: Osteomyelitis;
fragilitans Q78.0
Osteogenesis imperfecta Q78.0
Spurway's syndrome Q78.0
Syndrome See Also: Disease;
Adair-Dighton Q78.0
blue sclera Q78.0
Dighton's Q78.0
Eddowes' Q78.0
Ekman's Q78.0
Spurway's Q78.0
van der Hoeve's Q78.0
Vrolik's disease Q78.0
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Osteogenesis Imperfecta
collagen diseases characterized by brittle, osteoporotic, and easily fractured bones. it may also present with blue sclerae, loose joints, and imperfect dentin formation. most types are autosomal dominant and are associated with mutations in collagen type i.
Patient EducationClinical
Osteogenesis Imperfecta
Osteogenesis imperfecta (OI) is a genetic disorder in which bones fracture (break) easily. Sometimes the fractures happen for no known reason. OI can also cause weak muscles, brittle teeth, a curved spine, and hearing loss. OI is caused by one of several genes that aren't working properly.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Q78.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Q78.0Overview
What is the ICD-10 code for osteogenesis imperfecta?
The ICD-10-CM code for osteogenesis imperfecta is Q78.0 (sometimes written as Q780). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is Q78.0 (Other osteochondrodysplasias) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report osteogenesis imperfecta on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does Q78.0 group to?
When osteogenesis imperfecta is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 456, 566, 457, 565, 458, with relative weights from 0.7374 to 7.6211 depending on complications. Higher weights mean higher Medicare reimbursement.
Is Q78.0 a CC or MCC?
CMS lists Q78.0 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 10 closely related codes in its exclusion list.
Is Q78.0 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for osteogenesis imperfecta on inpatient claims. The code appears in the Congenital malformations and deformations of the musculoskeletal system (Q65-Q79) range of the CMS exempt list.
