2026 ICD-10-CM Diagnosis Code P53Hemorrhagic disease of newborn

ICD-10-CM Codes›P00–P96›P50-P61›P53

ICD-10-CM P53
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P53 is a billable ICD-10-CM diagnosis code for hemorrhagic disease of newborn. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 791, 793. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 28 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemorrhagic and hematologic disorders of newborn.

Code Identity

ICD-10-CM Code
P53
Billable Status
Yes — Valid for Submission
Code Describes
Hemorrhagic disease of newborn
Short Description
Hemorrhagic disease of newborn
Same as the full description in the CMS dataset.
Chapter
P50-P61
Hemorrhagic and hematological disorders of newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP50-P61Hemorrhagic and hematological disorders of newborn
CategoryP53Hemorrhagic disease of newborn
This CodeP53Hemorrhagic disease of newborn

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal fibrinolysis
  • Alpha-2-antiplasmin deficiency
  • Body skin hyperlaxity due to vitamin K dependent coagulation factor deficiency
  • Classic onset hemorrhagic disease of newborn due to vitamin K deficiency
  • Congenital alpha-2-antiplasmin deficiency
  • Decreased fibrinolysis
  • Deficiency of coagulation factor due to vitamin K deficiency
  • Deficiency of vitamin K1
  • Deficiency of vitamin K2
  • Disorder of vitamin K
  • Disorder of vitamin K1
  • Disorder of vitamin K2
  • Early onset diffuse bleeding diathesis secondary to vitamin K deficient hemorrhagic disease of fetus and newborn
  • Fibrinolytic bleeding syndrome
  • Hemorrhagic disease of the newborn due to factor II deficiency
  • Hemorrhagic disease of the newborn due to vitamin K deficiency
  • Hereditary combined coagulation factor deficiency
  • Hereditary combined deficiency of vitamin K-dependent clotting factors
  • Late onset diffuse bleeding diathesis secondary to vitamin K deficient hemorrhagic disease of fetus and newborn
  • Neonatal coagulation disorder
  • Vitamin K deficiency
  • Vitamin K deficiency coagulation disorder

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Vitamin K deficiency of newborn

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL011
Hemorrhagic and hematologic disorders of newborn
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Vitamin K Deficiency

    a nutritional condition produced by a deficiency of vitamin k in the diet, characterized by an increased tendency to hemorrhage (hemorrhagic disorders). such bleeding episodes may be particularly severe in newborn infants. (from cecil textbook of medicine, 19th ed, p1182)

  • Vitamin K Deficiency Bleeding

    hemorrhage caused by vitamin k deficiency.

Patient EducationClinical

Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P53 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
776.0 NB hemorrhagic disease
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P53Overview

What is the ICD-10 code for hemorrhagic disease of newborn?

The ICD-10-CM code for hemorrhagic disease of newborn is P53. It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is P53 (Hemorrhagic disease of newborn) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hemorrhagic disease of newborn on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does P53 group to?

When hemorrhagic disease of newborn is the principal diagnosis on an inpatient stay, it groups to MS-DRG 791, 793, with relative weights from 4.0590 to 4.1696 depending on complications. Higher weights mean higher Medicare reimbursement.

Is P53 a CC or MCC?

CMS lists P53 as a CC (complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 28 closely related codes in its exclusion list.

What is the ICD-9 equivalent of P53?

Under the General Equivalence Mappings, hemorrhagic disease of newborn converts to ICD-9-CM 776.0 (NB hemorrhagic disease). The mapping is a direct match.