2027 ICD-10-CM Diagnosis Code P53Hemorrhagic disease of newborn

ICD-10-CM Codes›P00–P96›P50-P61›P53

ICD-10-CM P53
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

P53 is a billable ICD-10-CM diagnosis code for hemorrhagic disease of newborn. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 28 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemorrhagic and hematologic disorders of newborn.

Code Identity

ICD-10-CM Code
P53
Billable Status
Yes — Valid for Submission
Code Describes
Hemorrhagic disease of newborn
Short Description
Hemorrhagic disease of newborn
Same as the full description in the CMS dataset.
Chapter
P50-P61
Hemorrhagic and hematological disorders of newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP50-P61Hemorrhagic and hematological disorders of newborn
CategoryP53Hemorrhagic disease of newborn
This CodeP53Hemorrhagic disease of newborn

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal fibrinolysis
  • Alpha-2-antiplasmin deficiency
  • Body skin hyperlaxity due to vitamin K dependent coagulation factor deficiency
  • Classic onset hemorrhagic disease of newborn due to vitamin K deficiency
  • Congenital alpha-2-antiplasmin deficiency
  • Decreased fibrinolysis
  • Deficiency of coagulation factor due to vitamin K deficiency
  • Deficiency of vitamin K1
  • Deficiency of vitamin K2
  • Disorder of vitamin K
  • Disorder of vitamin K1
  • Disorder of vitamin K2
  • Early onset diffuse bleeding diathesis secondary to vitamin K deficient hemorrhagic disease of fetus and newborn
  • Fibrinolytic bleeding syndrome
  • Hemorrhagic disease of the newborn due to factor II deficiency
  • Hemorrhagic disease of the newborn due to vitamin K deficiency
  • Hereditary combined coagulation factor deficiency
  • Hereditary combined deficiency of vitamin K-dependent clotting factors
  • Late onset diffuse bleeding diathesis secondary to vitamin K deficient hemorrhagic disease of fetus and newborn
  • Neonatal coagulation disorder
  • Vitamin K deficiency
  • Vitamin K deficiency coagulation disorder

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to P53: its own notes plus those printed at block P50-P61 and Chapter 16. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Vitamin K deficiency of newborn

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block P50-P61 Hemorrhagic and hematological disorders of newborn applies to 67 codes
  • congenital stenosis and stricture of bile ducts (Q44.3)
  • Crigler-Najjar syndrome (E80.5)
  • Dubin-Johnson syndrome (E80.6)
  • Gilbert syndrome (E80.4)
  • hereditary hemolytic anemias (D55-D58)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Notes

General instructions on how these codes are used.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • Codes from this chapter are for use on newborn records only, never on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name P53, its category, or a range that includes it.

Excludes1 3

These codes carry an Excludes1 note naming P53: they are not reported together with it, unless the two conditions are unrelated.

  • D68.4 Acquired coagulation factor deficiency
    vitamin K deficiency of newborn (P53)
  • D68.8 Other specified coagulation defects
    hemorrhagic disease of newborn (P53)
  • E56.1 Deficiency of vitamin K
    vitamin K deficiency of newborn (P53)

Excludes2 1

These codes carry an Excludes2 note naming P53: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block R70-R79 Abnormal findings on examination of blood, without diagnosis
    hemorrhagic and hematological disorders of newborn (P50-P61) names P50-P61, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL011
Hemorrhagic and hematologic disorders of newborn
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hemorrhagic Disease of Newborn

    a condition characterized as a coagulation disturbance in newborns due to vitamin k deficiency resulting in impaired production of coagulation factors ii, vii, ix, and x, and proteins c and s by the liver.

Patient EducationClinical

Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P53 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
776.0 NB hemorrhagic disease
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About P53Overview

What is the ICD-10 code for hemorrhagic disease of newborn?

The ICD-10-CM code for hemorrhagic disease of newborn is P53. It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is P53 (Hemorrhagic disease of newborn) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hemorrhagic disease of newborn on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does P53 group to?

When hemorrhagic disease of newborn is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, with relative weights from 4.1073 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is P53 a CC or MCC?

CMS lists P53 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 28 closely related codes in its exclusion list.

Can P53 be reported with Q44.3?

Not as a rule. The Excludes1 note at block P50-P61, which applies to P53, lists "congenital stenosis and stricture of bile ducts (Q44.3)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).