2026 ICD-10-CM Diagnosis Code N05.8Unspecified nephritic syndrome with other morphologic changes

ICD-10-CM Codes›N00–N99›N00-N08›N05

ICD-10-CM N05.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

N05.8 is a billable ICD-10-CM diagnosis code for unspecified nephritic syndrome with other morphologic changes. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 698 through 700. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nephritis; nephrosis; renal sclerosis.

Code Identity

ICD-10-CM Code
N05.8
Billable Status
Yes — Valid for Submission
Code Describes
Unspecified nephritic syndrome with other morphologic changes
Short Description
Unsp nephritic syndrome with other morphologic changes
Parent Code
N05
Unspecified nephritic syndrome

Code Classification

ChapterN00–N99Diseases of the genitourinary system
SectionN00-N08Glomerular diseases
CategoryN05Unspecified nephritic syndrome
This CodeN05.8Unspecified nephritic syndrome with other morphologic changes

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Collagenofibrotic glomerulopathy
  • Diffuse proliferative glomerulonephritis
  • Fibrillary glomerulonephritis
  • Focal embolic nephritis syndrome
  • Immune-complex glomerulonephritis
  • Light chain nephropathy
  • Light chain nephropathy due to plasma cell dyscrasia
  • Necrosis of capillary of kidney due to glomerular disease
  • Necrotizing glomerulonephritis
  • Proliferative glomerulonephritis
  • Recurrent proliferative glomerulonephritis
  • Renal involvement in malignant disease

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Unspecified nephritic syndrome with proliferative glomerulonephritis NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Glomerulonephritis
      • immune complex (circulating) NEC
    • Glomerulonephritis
      • necrotic, necrotizing NEC
    • Glomerulonephritis
      • proliferative NEC
    • Glomerulonephritis
      • specified pathology NEC
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • with
        • glomerular lesion
          • diffuse sclerosing
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • with
        • lesion of
          • glomerulonephritis, proliferative
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • with
        • specified morphological changes NEC
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • diffuse sclerosing
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • immune complex (circulating) NEC
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • necrotic, necrotizing NEC
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • proliferative NEC
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • sclerosing, diffuse
    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • specified pathology NEC
    • Nephropathy
      • proliferative NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR GEN001
Nephritis; nephrosis; renal sclerosis
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Immune Complex Glomerulonephritis

    inflammation of the glomeruli characterized by the accumulation of antibody-antigen immune complexes, resulting in glomerular damage and impaired kidney function.

  • C3 Glomerulonephritis|Complement-Mediated Membranoproliferative Glomerulonephritis

    glomerulonephritis characterized by c3 accumulation with little or absent deposition of immunoglobulin, in the absence of ultrastructural electron-dense transformation seen in dense deposit disease.

  • Chronic Glomerulonephritis with Lesion of Proliferative Glomerulonephritis

    a slowly progressive inflammation of the glomeruli occurring status post infection with streptococcus.

  • Dense Deposit Disease|Membranoproliferative Glomerulonephritis Type 2|Mesangiocapillary Glomerulonephritis Type 2

    proliferative glomerulonephritis characterized by activation of the alternative complement pathway, resulting in mesangial hypercellularity, endocapillary proliferation, and glomerular basement membrane intramembranous highly electron dense deposits.

  • Focal and Segmental Proliferative Glomerulonephritis

    glomerulonephritis characterized by proliferation of endothelial or mesangial cells, affecting the glomeruli in a focal and segmental pattern.

  • Immune Complex Mediated Membranoproliferative Glomerulonephritis|Membranoproliferative Glomerulonephritis Type I|Mesangiocapillary Glomerulonephritis Type 1

    glomerulonephritis characterized by mesangial proliferation, endocapillary proliferation, and glomerular capillary wall remodeling with immune complex deposits from classical complement pathway activation.

  • Membranoproliferative Glomerulonephritis Type 3 (AQ)|Mesangiocapillary Glomerulonephritis Type 3

    glomerulonephritis similar in appearance under light microscopy to membranoproliferative glomerulonephritis (mpgn) i, but with subepithelial or transmembranous and subendothelial deposits on electron microscopy.

  • Membranoproliferative Glomerulonephritis|Mesangiocapillary Glomerulonephritis

    inflammation of the glomeruli characterized by deposits at the intraglomerular mesangium, resulting in thickening of the glomerular basement membrane, activation of complement, and impaired kidney function secondary to damaged glomeruli.

  • Mesangial Proliferative Glomerulonephritis

    a focal inflammation of glomeruli secondary to mesangial cell proliferation and matrix deposition within the mesangium.

  • Nephrotic Syndrome with Lesion of Membranoproliferative Glomerulonephritis|Nephrotic Syndrome with Lesion of Lobular Glomerulonephritis|Nephrotic Syndrome with Lesion of Mesangiocapillary Glomerulonephritis

    a renal functional disorder characterized by proteinuria, edema, hyperlipidemia and hypoalbuminemia. it results from damage to the renal vascular filtration apparatus. it is further characterized by an inflammatory reaction of the glomerular capillaries due to the proliferation of mesangial cells, expansion of the mesangial matrix and deposition of immune complexes causing subsequent thickening of the glomerular basement membrane. sequelae may include hypertension, atherosclerosis, infection, hypercoagulablity and renal failure.

  • Nephrotic Syndrome with Lesion of Proliferative Glomerulonephritis

    a renal functional disorder characterized by proteinuria, edema, hyperlipidemia and hypoalbuminemia. it results from damage to the renal vascular filtration apparatus. it is further characterized by an inflammatory reaction of the glomerular capillaries due to the proliferation of mesangial cells and expansion of the mesangial matrix. sequelae may include hypertension, atherosclerosis, infection, hypercoagulablity and renal failure.

  • Post-Streptococcal Glomerulonephritis|Acute Proliferative Glomerulonephritis

    inflammation of the glomeruli status post infection with nephritogenic streptococci, most often group a beta hemolytic streptococcus.

  • Proliferative Glomerulonephritis

    a constellation of renal disorders characterized by an increase number of cells in the glomerulus; these disorders generally present with nephrotic syndrome, and generally progress to end stage renal failure over a matter of weeks to years, depending on the etiology. examples include iga nephropathy, membranoproliferative glomerulonephritis, and rapidly progressive glomerulonephritis.

  • Proliferative Glomerulonephritis with Monoclonal IgG Deposits|PGNMID

    a sub-type of monoclonal gammopathy of renal significance, characterized by restriction to a single immunoglobulin g heavy chain subclass and a single light chain isotype. light microscopy often shows an endocapillary proliferative or membranoproliferative glomerulopathy. electron microscopy reveals electron-dense subendothelial and mesangial deposits.

  • Diffuse Endocapillary Glomerulonephritis|Diffuse endocapillary proliferative glomerulonephritis

    glomerulonephritis characterized by endocapillary proliferation and the presence of inflammatory cells affecting 50% or more of all glomeruli.

Patient EducationClinical

Kidney Diseases

You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert N05.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
583.89 Nephritis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About N05.8Overview

Is N05.8 (Unspecified nephritic syndrome) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report unspecified nephritic syndrome with other morphologic changes on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does N05.8 group to?

When unspecified nephritic syndrome with other morphologic changes is the principal diagnosis on an inpatient stay, it groups to MS-DRG 698, 699, 700, with relative weights from 0.6899 to 1.6544 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of N05.8?

Under the General Equivalence Mappings, unspecified nephritic syndrome with other morphologic changes converts to ICD-9-CM 583.89 (nephritis NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.