Nephrotic syndrome (N04) ICD-10-CM
The N04 code range covers nephrotic syndrome with 19 ICD-10-CM diagnosis codes. 16 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- congenital nephrotic syndrome
- lipoid nephrosis
Codes in the N04 Range 19 codes · 16 billable
- N04 Nephrotic syndromeNon-billable
- N04.0 Nephrotic syndrome with minor glomerular abnormality
- N04.1 Nephrotic syndrome with focal and segmental glomerular lesions
- N04.2 Nephrotic syndrome with diffuse membranous glomerulonephritisNon-billable
- N04.20 Nephrotic syndrome with diffuse membranous glomerulonephritis, unspecified
- N04.21 Primary membranous nephropathy with nephrotic syndrome
- N04.22 Secondary membranous nephropathy with nephrotic syndrome
- N04.29 Other nephrotic syndrome with diffuse membranous glomerulonephritis
- N04.3 Nephrotic syndrome with diffuse mesangial proliferative glomerulonephritis
- N04.4 Nephrotic syndrome with diffuse endocapillary proliferative glomerulonephritis
- N04.5 Nephrotic syndrome with diffuse mesangiocapillary glomerulonephritis
- N04.6 Nephrotic syndrome with dense deposit disease
- N04.7 Nephrotic syndrome with diffuse crescentic glomerulonephritis
- N04.8 Nephrotic syndrome with other morphologic changes
- N04.9 Nephrotic syndrome with unspecified morphologic changes
- N04.A Nephrotic syndrome with C3 glomerulonephritis
- N04.B Nephrotic syndrome with immune complex membranoproliferative glomerulonephritis (IC-MPGN)Non-billable
- N04.B1 Nephrotic syndrome with idiopathic immune complex membranoproliferative glomerulonephritis (IC-MPGN)
- N04.B2 Nephrotic syndrome with secondary immune complex membranoproliferative glomerulonephritis (IC-MPGN)
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the N04 range.
Nephrosis
Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.
Nephrotic Syndrome
A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
About the N04 Code Range
Nephrotic syndrome involves severe protein loss in the urine. That loss can cause swelling, high blood pressure and other complications.
The subdivisions distinguish the glomerular changes or diseases named with the syndrome. N04.0 identifies a minor abnormality, while N04.1 identifies focal and segmental lesions. Other subdivisions name specific patterns of glomerular disease, including dense deposit disease and C3 glomerulonephritis. N04.8 and N04.9 distinguish other from unspecified changes.
N04.2 divides membranous disease into unspecified, primary, secondary and other forms. N04.B divides immune complex membranoproliferative disease into idiopathic and secondary forms.
Questions About This Page
How many billable codes are in the N04 range?
Of the 19 codes in this range, 16 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the N04 range classify?
The range classifies nephrotic syndrome. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
