2026 ICD-10-CM Diagnosis Code E53.9Vitamin B deficiency, unspecified

ICD-10-CM Codes›E00–E89›E50-E64›E53

ICD-10-CM E53.9
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E53.9 is a billable ICD-10-CM diagnosis code for vitamin B deficiency, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 640 through 641. Coders also document this condition as burning feet. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nutritional deficiencies.

Code Identity

ICD-10-CM Code
E53.9
Billable Status
Yes — Valid for Submission
Code Describes
Vitamin B deficiency, unspecified
Short Description
Vitamin B deficiency, unspecified
Same as the full description in the CMS dataset.
Parent Code
E53
Deficiency of other B group vitamins

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE50-E64Other nutritional deficiencies
CategoryE53Deficiency of other B group vitamins
This CodeE53.9Vitamin B deficiency, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Burning feet
  • Burning feet syndrome
  • Burning pain
  • Disorder of vitamin B
  • Vitamin B deficiency
  • Vitamin B-complex deficiency

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Avitaminosis(multiple)
      • B
    • Burning
      • feet syndrome
    • Deficiency, deficient
      • vitamin (multiple) NOS
        • B (complex) NOS
    • Deficiency, deficient
      • vitamin (multiple) NOS
        • group B
    • Encephalopathy(acute)
      • vitamin B deficiency NEC
    • Polyneuropathy(peripheral)
      • in (due to)
        • deficiency (of)
          • B (-complex) vitamins
    • Stomatitis(denture) (ulcerative)
      • due to
        • vitamin deficiency
          • B group NEC
    • Syndrome
      • burning feet

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END007
Nutritional deficiencies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Vitamin B Deficiency

    a condition due to deficiency in any member of the vitamin b complex. these b vitamins are water-soluble and must be obtained from the diet because they are easily lost in the urine. unlike the lipid-soluble vitamins, they cannot be stored in the body fat.

  • Vitamin B Deficiency

    abnormally low concentrations of vitamin b in the blood.

  • Burning Chest Pain|Burning Pain

    the sensation of chest pain described as an intense discomfort, similar to that experience as a result of a thermal burn, distinct from sharp, stabbing or aching, often related to nerves; sometimes used to describe gastric or esophageal pain.

  • Burning Pain

    a sensation of intensely hot or searing discomfort.

  • Have Shooting or Burning Pain in Fingers or Hands|Did you have shooting or burning pain in your fingers or hands

    a question about whether an individual has or had shooting or burning pain in their fingers or hands.

  • Have Shooting or Burning Pain in Toes or Feet|Did you have shooting or burning pain in your toes or feet

    a question about whether an individual has or had shooting or burning pain in their toes or feet.

  • MNSI - Burning Pain Legs/Feet|MNSI1-Ever Have Burning Pain Legs/Feet|MNSI1-Ever Have Burning Pain Legs/Feet|MNSI102

    michigan neuropathy screening instrument (mnsi) history; do you ever have any burning pain in your legs and/or feet?

  • SF-MPQ-2 - Hot-burning Pain|SFMP2-Hot-burning Pain|SFMP2-Hot-burning Pain|SFMP207

    short-form mcgill pain questionnaire-2 (short form mpq) hot-burning pain.

  • Have Shooting or Burning Pain in Fingers or Hands Question|Did you have shooting or burning pain in your fingers or hands|Have Shooting or Burning Pain in Fingers or Hands

    a question about whether an individual has or had shooting or burning pain in their fingers or hands.

  • Have Shooting or Burning Pain in Toes or Feet Question|Did you have shooting or burning pain in your toes or feet|Have Shooting or Burning Pain in Toes or Feet

    a question about whether an individual has or had shooting or burning pain in their toes or feet.

Patient EducationClinical

B Vitamins

The B vitamins are:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E53.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
266.9 Vitamin b deficiency NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E53.9Overview

Is E53.9 (Deficiency of other B group vitamins) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report vitamin B deficiency, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E53.9 group to?

When vitamin B deficiency, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 640, 641, with relative weights from 0.7782 to 1.3356 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E53.9?

Under the General Equivalence Mappings, vitamin B deficiency, unspecified converts to ICD-9-CM 266.9 (vitamin b deficiency NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.