2027 ICD-10-CM Diagnosis Code D49.89Neoplasm of unspecified behavior of other specified sites

ICD-10-CM Codes›C00–D49›D49›D49

ICD-10-CM D49.89
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D49.89 is a billable ICD-10-CM diagnosis code for neoplasm of unspecified behavior of other specified sites. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 826 through 830, 843 through 845. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D49.89
Billable Status
Yes — Valid for Submission
Code Describes
Neoplasm of unspecified behavior of other specified sites
Short Description
Neoplasm of unspecified behavior of other specified sites
Same as the full description in the CMS dataset.
Parent Code
Neoplasm of unspecified behavior of other specified sites

Code Classification

ChapterC00–D49Neoplasms
SectionD49Neoplasms of unspecified behavior
CategoryD49Neoplasms of unspecified behavior
This CodeD49.89Neoplasm of unspecified behavior of other specified sites

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute angle closure due to intraocular neoplasm
  • Acute angle closure of left eye due to intraocular neoplasm
  • Acute angle closure of right eye due to intraocular neoplasm
  • Adult heart neoplasm
  • Angle closure due to intraocular neoplasm
  • Angle closure glaucoma due to intraocular neoplasm
  • Angle closure glaucoma of left eye due to intraocular neoplasm
  • Angle closure glaucoma of right eye due to intraocular neoplasm
  • Angle closure of left eye due to intraocular neoplasm
  • Angle closure of right eye due to intraocular neoplasm
  • Anterior mediastinum mass
  • Asphyxia by circumferential chest wall tumor
  • Asphyxiation by sustained compression of chest
  • Bilateral acute angle closure
  • Bilateral acute angle closure due to intraocular neoplasm
  • Bilateral angle closure due to intraocular neoplasms
  • Bilateral angle closure glaucoma due to intraocular neoplasms
  • Bilateral glaucoma due to intraocular neoplasm
  • Bilateral ocular hypertension due to intraocular neoplasm
  • Bilateral secondary acute angle closure
  • Bilateral secondary angle closure glaucoma
  • Childhood neoplasm of heart
  • Conjunctival intraepithelial neoplasia
  • Extra-capsular extension of nodal tumor absent
  • Extra-capsular extension of nodal tumor indeterminate
  • Extra-capsular extension of nodal tumor present
  • Glaucoma due to intraocular neoplasm
  • Glaucoma of left eye due to intraocular neoplasm
  • Glaucoma of right eye due to intraocular neoplasm
  • Hypogastric lymphadenopathy
  • Immunodeficiency with thymoma
  • Intestinal lymphadenopathy
  • Location of tumor within eye cannot be determined
  • Myeloid and lymphoid neoplasm with fibroblast growth factor receptor 1 abnormality
  • Neoplasm affecting hematopoietic structure
  • Neoplasm of abdomen
  • Neoplasm of anterior mediastinum
  • Neoplasm of axilla
  • Neoplasm of axillary lymph nodes
  • Neoplasm of back
  • Neoplasm of bilateral eyes proper
  • Neoplasm of bone marrow
  • Neoplasm of bony and cartilaginous nasal skeleton
  • Neoplasm of bronchopulmonary lymph nodes
  • Neoplasm of cardiovascular system
  • Neoplasm of cheek
  • Neoplasm of chest wall
  • Neoplasm of ciliary body
  • Neoplasm of conjunctiva
  • Neoplasm of cornea
  • Neoplasm of cubital lymph nodes
  • Neoplasm of ear, nose, and throat
  • Neoplasm of endocardium
  • Neoplasm of epicardium
  • Neoplasm of epitrochlear lymph nodes
  • Neoplasm of extremity
  • Neoplasm of eye proper
  • Neoplasm of eye region
  • Neoplasm of face
  • Neoplasm of femoral lymph nodes
  • Neoplasm of flank
  • Neoplasm of foot
  • Neoplasm of forearm
  • Neoplasm of hand
  • Neoplasm of head
  • Neoplasm of head and neck
  • Neoplasm of heart
  • Neoplasm of heart AND/OR pericardium
  • Neoplasm of hip region
  • Neoplasm of hypogastric lymph nodes
  • Neoplasm of iliac lymph nodes
  • Neoplasm of infraclavicular lymph nodes
  • Neoplasm of inguinal lymph nodes
  • Neoplasm of inguinal region
  • Neoplasm of intercostal lymph nodes
  • Neoplasm of intestinal lymph nodes
  • Neoplasm of intra-abdominal lymph nodes
  • Neoplasm of intra-abdominal organs
  • Neoplasm of intrapelvic lymph node
  • Neoplasm of intrathoracic lymph nodes
  • Neoplasm of intrathoracic organs
  • Neoplasm of iridocorneal angle
  • Neoplasm of iris
  • Neoplasm of jaw
  • Neoplasm of lacrimal drainage system
  • Neoplasm of lacrimal gland
  • Neoplasm of lacrimal system
  • Neoplasm of lateral axillary lymph nodes
  • Neoplasm of left eye proper
  • Neoplasm of lower leg
  • Neoplasm of lower limb
  • Neoplasm of lower respiratory tract and mediastinum
  • Neoplasm of lymph node of face
  • Neoplasm of lymph node of head
  • Neoplasm of lymph node of lower limb
  • Neoplasm of lymph node of neck
  • Neoplasm of lymph nodes of multiple sites
  • Neoplasm of lymph nodes of upper limb
  • Neoplasm of mediastinal lymph nodes
  • Neoplasm of mediastinum
  • Neoplasm of mesenteric lymph nodes
  • Neoplasm of mesothelial tissue of pericardium
  • Neoplasm of myocardium
  • Neoplasm of nasolacrimal duct
  • Neoplasm of neck
  • Neoplasm of nose
  • Neoplasm of obturator lymph nodes
  • Neoplasm of occipital lymph nodes
  • Neoplasm of ocular adnexa
  • Neoplasm of orbit
  • Neoplasm of oropharynx
  • Neoplasm of paramammary lymph nodes
  • Neoplasm of parametrial lymph nodes
  • Neoplasm of parametrium
  • Neoplasm of pararectal lymph nodes
  • Neoplasm of paravaginal lymph nodes
  • Neoplasm of parotid lymph nodes
  • Neoplasm of pectoral axillary lymph nodes
  • Neoplasm of pelvis
  • Neoplasm of pericardium
  • Neoplasm of popliteal lymph nodes
  • Neoplasm of posterior mediastinum
  • Neoplasm of preauricular lymph nodes
  • Neoplasm of presacral region
  • Neoplasm of rectovaginal septum
  • Neoplasm of rectovesical septum
  • Neoplasm of retroperitoneal lymph nodes
  • Neoplasm of retropharyngeal lymph nodes
  • Neoplasm of right eye proper
  • Neoplasm of sacrococcygeal region
  • Neoplasm of scalene lymph nodes
  • Neoplasm of sclera
  • Neoplasm of shoulder
  • Neoplasm of submandibular lymph nodes
  • Neoplasm of submental lymph nodes
  • Neoplasm of superficial inguinal lymph nodes
  • Neoplasm of supraclavicular lymph nodes
  • Neoplasm of supraclavicular region
  • Neoplasm of thigh
  • Neoplasm of thorax
  • Neoplasm of thymus
  • Neoplasm of tibial lymph nodes
  • Neoplasm of tracheobronchial lymph nodes
  • Neoplasm of trunk
  • Neoplasm of upper aerodigestive tract
  • Neoplasm of upper arm
  • Neoplasm of upper limb
  • Neoplasm of uveal tract
  • Ocular hypertension due to intraocular neoplasm
  • Ocular hypertension due to intraocular neoplasm of left eye
  • Ocular hypertension due to intraocular neoplasm of right eye
  • OSSN - ocular surface squamous neoplasia
  • Pararectal lymphadenopathy
  • Pseudo Meigs syndrome
  • Retroperitoneal lymphadenopathy
  • Sentinel conjunctival vessel
  • Thymoma
  • Vascularization of tumor tissue

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D49.89: its own notes plus those printed at D49.8, D49, and Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From D49 Neoplasms of unspecified behavior applies to 14 codes
  • 'growth' NOS
  • neoplasm NOS
  • new growth NOS
  • tumor NOS

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From D49.8 Neoplasm of unspecified behavior of other specified sites applies to 2 codes
  • neoplasm of unspecified behavior of eyelid (skin) (D49.2)
  • neoplasm of unspecified behavior of eyelid cartilage (D49.2)
  • neoplasm of unspecified behavior of great vessels (D49.2)
  • neoplasm of unspecified behavior of optic nerve (D49.7)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From D49 Neoplasms of unspecified behavior applies to 14 codes
  • neoplasms of uncertain behavior (D37-D44, D48)

Notes

General instructions on how these codes are used.

From D49 Neoplasms of unspecified behavior applies to 14 codes
  • Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth.
From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D49.89, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming D49.89: they are not reported together with it, unless the two conditions are unrelated.

  • D49.2 Neoplasm of unspecified behavior of bone, soft tissue, and skin
    neoplasm of unspecified behavior of bone marrow (D49.89)
  • Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
    neoplasms of unspecified behavior (D49.-) names D49.-, which includes this code

Notes 1

These notes mention D49.89.

  • D49 Neoplasms of unspecified behavior
    Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth. names D49, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
abdomen, abdominalC76.2C79.8D09.8D36.7D48.7D49.89
abdomen, abdominal › cavityC76.2C79.8D09.8D36.7D48.7D49.89
abdomen, abdominal › organC76.2C79.8D09.8D36.7D48.7D49.89
abdomen, abdominal › visceraC76.2C79.8D09.8D36.7D48.7D49.89
abdominopelvicC76.8C79.8–D36.7D48.7D49.89
ankle NECC76.5C79.89D04.7D36.7D48.7D49.89
antecubital fossa or spaceC76.4C79.89D04.6D36.7D48.7D49.89
arm NECC76.4C79.89D04.6D36.7D48.7D49.89
atrium, cardiacC38.0C79.89–D15.1D48.7D49.89
axilla, axillaryC76.1C79.89D09.8D36.7D48.7D49.89
back NECC76.8C79.89D04.5D36.7D48.7D49.89
bone (periosteum) › marrow NEC (any bone)C96.9C79.52––D47.9D49.89
buttock NECC76.3C79.89D04.5D36.7D48.7D49.89
calfC76.5C79.89D04.7D36.7D48.7D49.89
cervical regionC76.0C79.89D09.8D36.7D48.7D49.89
cheekC76.0C79.89D09.8D36.7D48.7D49.89
chest (wall) NECC76.1C79.89D09.8D36.7D48.7D49.89
ciliary bodyC69.4C79.49D09.2D31.4D48.7D49.89
conjunctivaC69.0C79.49D09.2D31.0D48.7D49.89
connective tissue NEC › orbitC69.6C79.49D09.2D31.6D48.1D49.89
cornea (limbus)C69.1C79.49D09.2D31.1D48.7D49.89
crystalline lensC69.4C79.49D09.2D31.4D48.7D49.89
elbow NECC76.4C79.89D04.6D36.7D48.7D49.89
endocardiumC38.0C79.89–D15.1D48.7D49.89
epicardiumC38.0C79.89–D15.1D48.7D49.89
extraocular muscleC69.6C79.49D09.2D31.6D48.7D49.89
extrarectalC76.3C79.89D09.8D36.7D48.7D49.89
extremityC76.8C79.89D04.8D36.7D48.7D49.89
extremity › lowerC76.5C79.89D04.7D36.7D48.7D49.89
extremity › upperC76.4C79.89D04.6D36.7D48.7D49.89
eye NECC69.9C79.49D09.2D31.9D48.7D49.89
eyeballC69.9C79.49D09.2D31.9D48.7D49.89
face NECC76.0C79.89D04.39D36.7D48.7D49.89
finger NECC76.4C79.89D04.6D36.7D48.7D49.89
flank NECC76.8C79.89D04.5D36.7D48.7D49.89
foot NECC76.5C79.89D04.7D36.7D48.7D49.89
forearm NECC76.4C79.89D04.6D36.7D48.7D49.89
fossa (of) › ischiorectalC76.3C79.89D09.8D36.7D48.7D49.89
gluteal regionC76.3C79.89D04.5D36.7D48.7D49.89
groin NECC76.3C79.89D04.5D36.7D48.7D49.89
hand NECC76.4C79.89D04.6D36.7D48.7D49.89
head NECC76.0C79.89D04.4D36.7D48.7D49.89
heartC38.0C79.89–D15.1D48.7D49.89
heel NECC76.5C79.89D04.7D36.7D48.7D49.89
hip NECC76.5C79.89D04.7D36.7D48.7D49.89
infraclavicular (region)C76.1C79.89D04.5D36.7D48.7D49.89
inguinal (region)C76.3C79.89D04.5D36.7D48.7D49.89
intra-abdominalC76.2C79.89D09.8D36.7D48.7D49.89
intraocularC69.9C79.49D09.2D31.9D48.7D49.89
intraorbitalC69.6C79.49D09.2D31.6D48.7D49.89
intrathoracic (cavity) (organs)C76.1C79.89D09.8D15.9D48.7D49.89
irisC69.4C79.49D09.2D31.4D48.7D49.89
ischiorectal (fossa)C76.3C79.89D09.8D36.7D48.7D49.89
jawC76.0C79.89D09.8D36.7D48.7D49.89
knee NECC76.5C79.89D04.7D36.7D48.7D49.89
lacrimal › canaliculiC69.5C79.49D09.2D31.5D48.7D49.89
lacrimal › duct (nasal)C69.5C79.49D09.2D31.5D48.7D49.89
lacrimal › glandC69.5C79.49D09.2D31.5D48.7D49.89
lacrimal › punctumC69.5C79.49D09.2D31.5D48.7D49.89
lacrimal › sacC69.5C79.49D09.2D31.5D48.7D49.89
leg NECC76.5C79.89D04.7D36.7D48.7D49.89
lens, crystallineC69.4C79.49D09.2D31.4D48.7D49.89
limbC76.8C79.89D04.8D36.7D48.7D49.89
limb › lowerC76.5C79.89D04.7D36.7D48.7D49.89
limb › upperC76.4C79.89D04.6D36.7D48.7D49.89
limbus of corneaC69.1C79.49D09.2D31.1D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary)–C77.9–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › abdominal–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › aortic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › arm–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › auricular (anterior) (posterior)–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › axilla, axillary–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › brachial–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › bronchial–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › bronchopulmonary–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › celiac–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › cervical–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › cervicofacial–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › Cloquet–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › colic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › common duct–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › cubital–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › diaphragmatic–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › epigastric, inferior–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › epitrochlear–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › esophageal–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › face–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › femoral–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › gastric–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › groin–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › head–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › hepatic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › hilar (pulmonary)–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › hilar (pulmonary) › splenic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › hypogastric–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › ileocolic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › iliac–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › infraclavicular–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › inguina, inguinal–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › innominate–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › intercostal–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › intestinal–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › intrabdominal–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › intrapelvic–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › intrathoracic–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › jugular–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › leg–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › limb › lower–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › limb › upper–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › lower limb–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › lumbar–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › mandibular–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › mediastinal–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › mesenteric (inferior) (superior)–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › midcolic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › multiple sites in categories C77.0 - C77.5–C77.8–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › neck–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › obturator–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › occipital–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › pancreatic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › para-aortic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › paracervical–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › parametrial–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › parasternal–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › parotid–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › pectoral–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › pelvic–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › peri-aortic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › peripancreatic–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › popliteal–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › porta hepatis–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › portal–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › preauricular–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › prelaryngeal–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › presymphysial–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › pretracheal–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › pulmonary (hiler)–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › pyloric–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › retroperitoneal–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › retropharyngeal–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › Rosenmuller's–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › sacral–C77.5–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › scalene–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › site NEC–C77.9–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › splenic (hilar)–C77.2–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › subclavicular–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › subinguinal–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › sublingual–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › submandibular–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › submaxillary–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › submental–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › subscapular–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › supraclavicular–C77.0–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › thoracic–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › tibial–C77.4–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › tracheal–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › tracheobronchial–C77.1–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › upper limb–C77.3–D36.0D48.7D49.89
lymph, lymphatic channel NEC › gland (secondary) › Virchow's–C77.0–D36.0D48.7D49.89
marrow (bone) NECC96.9C79.52––D47.9D49.89
mediastinum, mediastinalC38.3C78.1–D15.2D38.3D49.89
mediastinum, mediastinal › anteriorC38.1C78.1–D15.2D38.3D49.89
mediastinum, mediastinal › posteriorC38.2C78.1–D15.2D38.3D49.89
muscle [See Also: Neoplasm, connective tissue] › extraocularC69.6C79.49D09.2D31.6D48.7D49.89
myocardiumC38.0C79.89–D15.1D48.7D49.89
myopericardiumC38.0C79.89–D15.1D48.7D49.89
nasolacrimal ductC69.5C79.49D09.2D31.5D48.7D49.89
neck NECC76.0C79.89D09.8D36.7D48.7D49.89
nose, nasalC76.0C79.89D09.8D36.7D48.7D49.89
orbitC69.6C79.49D09.2D31.6D48.7D49.89
orbit › eyeC69.6C79.49D09.2D31.6D48.7D49.89
orbit › soft partsC69.6C79.49D09.2D31.6D48.7D49.89
pararectalC76.3C79.89–D36.7D48.7D49.89
parasagittal (region)C76.0C79.89D09.8D36.7D48.7D49.89
paraurethralC76.3C79.89–D36.7D48.7D49.89
paravaginalC76.3C79.89–D36.7D48.7D49.89
pelvis, pelvicC76.3C79.89D09.8D36.7D48.7D49.89
pelvis, pelvic › floorC76.3C79.89D09.8D36.7D48.7D49.89
pelvis, pelvic › visceraC76.3C79.89D09.8D36.7D48.7D49.89
pelvis, pelvic › wallC76.3C79.89D09.8D36.7D48.7D49.89
pelvo-abdominalC76.8C79.89D09.8D36.7D48.7D49.89
pericardiumC38.0C79.89–D15.1D48.7D49.89
perineumC76.3C79.89D09.8D36.7D48.7D49.89
perirectal (tissue)C76.3C79.89–D36.7D48.7D49.89
peritonsillar (tissue)C76.0C79.89D09.8D36.7D48.7D49.89
periurethral tissueC76.3C79.89–D36.7D48.7D49.89
popliteal fossa or spaceC76.5C79.89D04.7D36.7D48.7D49.89
presacral (region)C76.3C79.89–D36.7D48.7D49.89
rectovaginal septum or wallC76.3C79.89D09.8D36.7D48.7D49.89
rectovesical septumC76.3C79.89D09.8D36.7D48.7D49.89
retrobulbarC69.6C79.49–D31.6D48.7D49.89
retro-orbitalC76.0C79.89D09.8D36.7D48.7D49.89
retrovesical (septum)C76.3C79.89D09.8D36.7D48.7D49.89
sacrococcyx, sacrococcygeal › regionC76.3C79.89D09.8D36.7D48.7D49.89
scapular regionC76.1C79.89D09.8D36.7D48.7D49.89
scleraC69.4C79.49D09.2D31.4D48.7D49.89
septum › rectovaginalC76.3C79.89D09.8D36.7D48.7D49.89
septum › rectovesicalC76.3C79.89D09.8D36.7D48.7D49.89
shoulder NECC76.4C79.89D04.6D36.7D48.7D49.89
specified site NECC76.8C79.89D09.8D36.7D48.7D49.89
spine, spinal (column) › marrow NECC96.9C79.52––D47.9D49.89
submentalC76.0C79.89D09.8D36.7D48.7D49.89
substernalC38.1C78.1–D15.2D38.3D49.89
supraclavicular regionC76.0C79.89D09.8D36.7D48.7D49.89
temporal › regionC76.0C79.89D09.8D36.7D48.7D49.89
thigh NECC76.5C79.89D04.7D36.7D48.7D49.89
thorax, thoracic (cavity) (organs NEC)C76.1C79.89D09.8D36.7D48.7D49.89
thorax, thoracic (cavity) (organs NEC) › wall NECC76.1C79.89D09.8D36.7D48.7D49.89
thumb NECC76.4C79.89D04.6D36.7D48.7D49.89
thymus (gland)C37C79.89D09.3D15.0D38.4D49.89
toe NECC76.5C79.89D04.7D36.7D48.7D49.89
trunk NECC76.8C79.89D04.5D36.7D48.7D49.89
uveal tractC69.4C79.49D09.2D31.4D48.7D49.89
ventricle (cerebral) (floor) (lateral) (third) › cardiac (left) (right)C38.0C79.89–D15.1D48.7D49.89
vertebra (column) › marrow NECC96.9C79.52––D47.9D49.89
vesicorectalC76.3C79.82D09.8D36.7D48.7D49.89
Virchow's glandC77.0C77.0–D36.0D48.7D49.89
viscera NECC76.8C79.89D09.8D36.7D48.7D49.89
wrist NECC76.4C79.89D04.6D36.7D48.7D49.89

Convert D49.89 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
239.89 Neoplasm other sites NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D49.89Overview

What is the ICD-10 code for neoplasm of unspecified behavior of other specified sites?

The ICD-10-CM code for neoplasm of unspecified behavior of other specified sites is D49.89 (sometimes written as D4989). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D49.89 (Neoplasm of unspecified behavior of other specified sites) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of unspecified behavior of other specified sites on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D49.89 group to?

When neoplasm of unspecified behavior of other specified sites is the principal diagnosis on an inpatient stay, it groups to MS-DRG 844, 827, 829, 843, 828, 826, 830, 845, with relative weights from 0.8443 to 4.7560 depending on complications. Higher weights mean higher Medicare reimbursement.

Can D49.89 be reported with D49.2?

Not as a rule. The Excludes1 note at D49.8, which applies to D49.89, lists "neoplasm of unspecified behavior of eyelid (skin) (D49.2)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of D49.89?

Under the General Equivalence Mappings, neoplasm of unspecified behavior of other specified sites converts to ICD-9-CM 239.89 (neoplasm other sites NOS). The mapping is a direct match.