2027 ICD-10-CM Diagnosis Code A52.17General paresis

ICD-10-CM Codes›A00–B99›A50-A64›A52

ICD-10-CM A52.17
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

A52.17 is a billable ICD-10-CM diagnosis code for general paresis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 56 through 57. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 96 closely related codes. Coders also document this condition as chronic infectious disease of central nervous system. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified CNS infection and poliomyelitis and Sexually transmitted infections (excluding HIV and hepatitis).

Code Identity

ICD-10-CM Code
A52.17
Billable Status
Yes — Valid for Submission
Code Describes
General paresis
Short Description
General paresis
Same as the full description in the CMS dataset.
Parent Code
A52.1
Symptomatic neurosyphilis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA50-A64Infections with a predominantly sexual mode of transmission
CategoryA52Late syphilis
This CodeA52.17General paresis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Chronic infectious disease of central nervous system
  • Dementia associated with neurosyphilis
  • General paresis - neurosyphilis
  • Late quaternary neurosyphilis
  • Spastic spinal syphilitic paralysis
  • Tabetic neurosyphilis
  • Taboparesis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to A52.17: its own notes plus those printed at block A50-A64 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Dementia paralytica

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block A50-A64 Infections with a predominantly sexual mode of transmission applies to 142 codes
  • nonspecific and nongonococcal urethritis (N34.1)
  • Reiter's disease (M02.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block A50-A64 Infections with a predominantly sexual mode of transmission applies to 142 codes
  • human immunodeficiency virus [HIV] disease (B20)
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name A52.17, its category, or a range that includes it.

Applicable To 1

These notes mention A52.17.

  • O98.1 Syphilis complicating pregnancy, childbirth and the puerperium
    Conditions in A50-A53 names A50-A53, which includes this code

Excludes1 1

These codes carry an Excludes1 note naming A52.17: they are not reported together with it, unless the two conditions are unrelated.

  • G99.8 Other specified disorders of nervous system in diseases classified elsewhere
    syphilis (A52.1-) names A52.1-, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming A52.17: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block A65-A69 Other spirochetal diseases
    syphilis (A50-A53) names A50-A53, which includes this code

Code First 1

These codes say to code first a condition named in the note, and A52.17 is one of the conditions named.

  • F02 Dementia in other diseases classified elsewhere
    neurosyphilis (A52.17)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS003
Other specified CNS infection and poliomyelitis
Default principal diagnosis: inpatient No · outpatient No
CCSR INF010
Sexually transmitted infections (excluding HIV and hepatitis)
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Tertiary Syphilis

    a stage of syphilis that occurs fifteen to thirty years after the initial infection; it can include gumma formation and cardiovascular or central nervous system involvement (neurosyphilis).

Patient EducationClinical

Dementia

Dementia is a loss of mental functions that is severe enough to affect your daily life and activities. These functions include:

The full article covers:

  • What is dementia?
  • What are the types of dementia?
  • Who is at risk for dementia?
  • What are the symptoms of dementia?
  • How is dementia diagnosed?
  • What are the treatments for dementia?
  • Can dementia be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A52.17 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
094.1 General paresis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About A52.17Overview

What is the ICD-10 code for general paresis?

The ICD-10-CM code for general paresis is A52.17 (sometimes written as A5217). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is A52.17 (Symptomatic neurosyphilis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report general paresis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does A52.17 group to?

When general paresis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 57, 56, with relative weights from 1.2835 to 2.2649 depending on complications. Higher weights mean higher Medicare reimbursement.

Is A52.17 a CC or MCC?

CMS lists A52.17 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 96 closely related codes in its exclusion list.

Can A52.17 be reported with N34.1?

Not as a rule. The Excludes1 note at block A50-A64, which applies to A52.17, lists "nonspecific and nongonococcal urethritis (N34.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).