2026 ICD-10-CM Diagnosis Code A53Other and unspecified syphilis

ICD-10-CM Codes›A00–B99›A50-A64›A53

ICD-10-CM A53
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

A53 is a non-billable ICD-10-CM category code for other and unspecified syphilis, so it cannot be submitted on claims. Use a more specific code from this category instead, such as A53.0 and A53.9.

Code Identity

ICD-10-CM Code
A53
Billable Status
No — Non-Billable Category
Code Describes
Other and unspecified syphilis
Chapter
A50-A64
Infections with a predominantly sexual mode of transmission

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA50-A64Infections with a predominantly sexual mode of transmission
CategoryA53Other and unspecified syphilis
This CodeA53Other and unspecified syphilis

Specific Coding for Other and unspecified syphilisOverview

Non-specific codes like A53 require more characters. Use one of these billable codes instead:

  • Use A53.0 for Latent syphilis, unspecified as early or late

  • Use A53.9 for Syphilis, unspecified

Patient EducationClinical

Syphilis

Syphilis is a sexually transmitted infection (STI) caused by bacteria. It infects the genital area, lips, mouth, or anus of both men and women. You usually get syphilis from sexual contact with someone who has it. It can also pass from mother to baby during pregnancy.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About A53Overview

Is A53 (Other and unspecified syphilis) a billable code?

No. This is a category header that groups the codes for other and unspecified syphilis, and headers cannot be submitted on claims. Claims for other and unspecified syphilis need a more specific code from this category, such as A53.0 and A53.9.