ICD-10-CM Code A52.2

Asymptomatic neurosyphilis

Version 2020 Billable Code

Valid for Submission

A52.2 is a billable code used to specify a medical diagnosis of asymptomatic neurosyphilis. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code A52.2 might also be used to specify conditions or terms like asymptomatic neurosyphilis or asymptomatic secondary neurosyphilis or late quaternary neurosyphilis or secondary neurosyphilis.

Short Description:Asymptomatic neurosyphilis
Long Description:Asymptomatic neurosyphilis

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code A52.2 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Asymptomatic neurosyphilis
  • Asymptomatic secondary neurosyphilis
  • Late quaternary neurosyphilis
  • Secondary neurosyphilis

Clinical Information

  • NEUROSYPHILIS-. infections of the central nervous system caused by treponema pallidum which present with a variety of clinical syndromes. the initial phase of infection usually causes a mild or asymptomatic meningeal reaction. the meningovascular form may present acutely as brain infarction. the infection may also remain subclinical for several years. late syndromes include general paresis; tabes dorsalis; meningeal syphilis; syphilitic optic atrophy; and spinal syphilis. general paresis is characterized by progressive dementia; dysarthria; tremor; myoclonus; seizures; and argyll robertson pupils. adams et al. principles of neurology 6th ed pp722 8

Convert A52.2 to ICD-9

  • 094.3 - Asymptomat neurosyphilis

Code Classification

  • Certain infectious and parasitic diseases (A00–B99)
    • Infections with a predominantly sexual mode of transmission (A50-A64)
      • Late syphilis (A52)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


Syphilis is a sexually transmitted disease caused by bacteria. It infects the genital area, lips, mouth, or anus of both men and women. You usually get syphilis from sexual contact with someone who has it. It can also pass from mother to baby during pregnancy.

The early stage of syphilis usually causes a single, small, painless sore. Sometimes it causes swelling in nearby lymph nodes. If you do not treat it, syphilis usually causes a non-itchy skin rash, often on your hands and feet. Many people do not notice symptoms for years. Symptoms can go away and come back.

The sores caused by syphilis make it easier to get or give someone HIV during sex. If you are pregnant, syphilis can cause complications, or you could lose your baby. In rare cases, syphilis causes serious health problems and even death.

Syphilis is easy to cure with antibiotics if you catch it early. Correct usage of latex condoms greatly reduces, but does not completely eliminate, the risk of catching or spreading syphilis. The most reliable way to avoid infection is to not have anal, vaginal, or oral sex.

Centers for Disease Control and Prevention

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