Syphilis, syphilitic (acquired)

Alphabetical Index

Use the alphabetical index for the main term syphilis, syphilitic (acquired) to review the available sub terms and properly select the ICD-10 code with the highest degree of specificity. Instructional notations will guide the coder with information such as "see", "see also", "with", "without", "due to", and "code by site".

  • Syphilis, syphilitic (acquired) - A53.9 Syphilis, unspecified
    • abdomen (late) - A52.79 Other symptomatic late syphilis
    • acoustic nerve - A52.15 Late syphilitic neuropathy
    • adenopathy (secondary) - A51.49 Other secondary syphilitic conditions
    • adrenal (gland) (with cortical hypofunction) - A52.79 Other symptomatic late syphilis
    • age under 2 years NOS - See Also: Syphilis, congenital, early;
      • acquired - A51.9 Early syphilis, unspecified
    • alopecia (secondary) - A51.32 Syphilitic alopecia
    • anemia (late) - A52.79 Other symptomatic late syphilis
    • aneurysm (aorta) (ruptured) - A52.01 Syphilitic aneurysm of aorta
      • central nervous system - A52.05 Other cerebrovascular syphilis
      • congenital - A50.54 Late congenital cardiovascular syphilis
    • anus (late) - A52.74 Syphilis of liver and other viscera
      • primary - A51.1 Primary anal syphilis
      • secondary - A51.39 Other secondary syphilis of skin
    • aorta (arch) (abdominal) (thoracic) - A52.02 Syphilitic aortitis
      • aneurysm - A52.01 Syphilitic aneurysm of aorta
    • aortic (insufficiency) (regurgitation) (stenosis) - A52.03 Syphilitic endocarditis
      • aneurysm - A52.01 Syphilitic aneurysm of aorta
    • arachnoid (adhesive) (cerebral) (spinal) - A52.13 Late syphilitic meningitis
    • asymptomatic - See: Syphilis, latent;
    • ataxia (locomotor) - A52.11 Tabes dorsalis
    • atrophoderma maculatum - A51.39 Other secondary syphilis of skin
    • auricular fibrillation - A52.06 Other syphilitic heart involvement
    • bladder (late) - A52.76 Other genitourinary symptomatic late syphilis
    • bone - A52.77 Syphilis of bone and joint
      • secondary - A51.46 Secondary syphilitic osteopathy
    • brain - A52.17 General paresis
    • breast (late) - A52.79 Other symptomatic late syphilis
    • bronchus (late) - A52.72 Syphilis of lung and bronchus
    • bubo (primary) - A51.0 Primary genital syphilis
    • bulbar palsy - A52.19 Other symptomatic neurosyphilis
    • bursa (late) - A52.78 Syphilis of other musculoskeletal tissue
    • cardiac decompensation - A52.06 Other syphilitic heart involvement
    • cardiovascular - A52.00 Cardiovascular syphilis, unspecified
    • central nervous system (late) (recurrent) (relapse) (tertiary) - A52.3 Neurosyphilis, unspecified
      • aneurysm - A52.05 Other cerebrovascular syphilis
      • congenital - A50.40 Late congenital neurosyphilis, unspecified
      • juvenile - A50.40 Late congenital neurosyphilis, unspecified
      • remission in (sustained) - A52.3 Neurosyphilis, unspecified
      • serology doubtful, negative, or positive - A52.3 Neurosyphilis, unspecified
      • specified nature or site NEC - A52.19 Other symptomatic neurosyphilis
      • vascular - A52.05 Other cerebrovascular syphilis
      • with
        • ataxia - A52.11 Tabes dorsalis
        • general paralysis - A52.17 General paresis
          • juvenile - A50.45 Juvenile general paresis
        • paresis (general) - A52.17 General paresis
          • juvenile - A50.45 Juvenile general paresis
        • tabes (dorsalis) - A52.11 Tabes dorsalis
          • juvenile - A50.45 Juvenile general paresis
        • taboparesis - A52.17 General paresis
          • juvenile - A50.45 Juvenile general paresis
    • cerebral - A52.17 General paresis
      • meningovascular - A52.13 Late syphilitic meningitis
      • nerves (multiple palsies) - A52.15 Late syphilitic neuropathy
      • sclerosis - A52.17 General paresis
      • thrombosis - A52.05 Other cerebrovascular syphilis
    • cerebrospinal (tabetic type) - A52.12 Other cerebrospinal syphilis
    • cerebrovascular - A52.05 Other cerebrovascular syphilis
    • cervix (late) - A52.76 Other genitourinary symptomatic late syphilis
    • chancre (multiple) - A51.0 Primary genital syphilis
      • extragenital - A51.2 Primary syphilis of other sites
      • Rollet's - A51.0 Primary genital syphilis
    • Charcot's joint - A52.16 Charcot's arthropathy (tabetic)
    • chorioretinitis - A51.43 Secondary syphilitic oculopathy
      • congenital - A50.01 Early congenital syphilitic oculopathy
      • late - A52.71 Late syphilitic oculopathy
      • prenatal - A50.01 Early congenital syphilitic oculopathy
    • choroiditis - See: Syphilitic chorioretinitis;
    • choroidoretinitis - See: Syphilitic chorioretinitis;
    • ciliary body (secondary) - A51.43 Secondary syphilitic oculopathy
      • late - A52.71 Late syphilitic oculopathy
    • colon (late) - A52.74 Syphilis of liver and other viscera
    • combined spinal sclerosis - A52.11 Tabes dorsalis
    • condyloma (latum) - A51.31 Condyloma latum
    • congenital - A50.9 Congenital syphilis, unspecified
      • chorioretinitis, choroiditis - A50.01 Early congenital syphilitic oculopathy
      • early, or less than 2 years after birth NEC - A50.2 Early congenital syphilis, unspecified
        • latent (without manifestations) - A50.1 Early congenital syphilis, latent
          • negative spinal fluid test - A50.1 Early congenital syphilis, latent
          • serology positive - A50.1 Early congenital syphilis, latent
        • symptomatic - A50.09 Other early congenital syphilis, symptomatic
          • cutaneous - A50.06 Early cutaneous congenital syphilis
          • mucocutaneous - A50.07 Early mucocutaneous congenital syphilis
          • oculopathy - A50.01 Early congenital syphilitic oculopathy
          • osteochondropathy - A50.02 Early congenital syphilitic osteochondropathy
          • pharyngitis - A50.03 Early congenital syphilitic pharyngitis
          • pneumonia - A50.04 Early congenital syphilitic pneumonia
          • rhinitis - A50.05 Early congenital syphilitic rhinitis
          • visceral - A50.08 Early visceral congenital syphilis
        • with manifestations - See: Syphilis, congenital, early, symptomatic;
      • interstitial keratitis - A50.31 Late congenital syphilitic interstitial keratitis
      • juvenile neurosyphilis - A50.45 Juvenile general paresis
      • late, or 2 years or more after birth NEC - A50.7 Late congenital syphilis, unspecified
        • chorioretinitis, choroiditis - A50.32 Late congenital syphilitic chorioretinitis
        • interstitial keratitis - A50.31 Late congenital syphilitic interstitial keratitis
        • juvenile neurosyphilis - A50.45 Juvenile general paresis
        • latent (without manifestations) - A50.6 Late congenital syphilis, latent
          • negative spinal fluid test - A50.6 Late congenital syphilis, latent
          • serology positive - A50.6 Late congenital syphilis, latent
        • symptomatic or with manifestations NEC - A50.59 Other late congenital syphilis, symptomatic
          • arthropathy - A50.55 Late congenital syphilitic arthropathy
          • cardiovascular - A50.54 Late congenital cardiovascular syphilis
          • Clutton's joints - A50.51 Clutton's joints
          • Hutchinson's teeth - A50.52 Hutchinson's teeth
          • Hutchinson's triad - A50.53 Hutchinson's triad
          • osteochondropathy - A50.56 Late congenital syphilitic osteochondropathy
          • saddle nose - A50.57 Syphilitic saddle nose
      • with
        • paresis (general) - A50.45 Juvenile general paresis
        • tabes (dorsalis) - A50.45 Juvenile general paresis
        • taboparesis - A50.45 Juvenile general paresis
    • conjugal - A53.9 Syphilis, unspecified
    • conjunctiva (late) - A52.71 Late syphilitic oculopathy
    • contact - Z20.2 Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission
    • cord bladder - A52.19 Other symptomatic neurosyphilis
    • cornea, late - A52.71 Late syphilitic oculopathy
    • coronary (artery) (sclerosis) - A52.06 Other syphilitic heart involvement
    • coryza, congenital - A50.05 Early congenital syphilitic rhinitis
    • cranial nerve - A52.15 Late syphilitic neuropathy
      • multiple palsies - A52.15 Late syphilitic neuropathy
    • cutaneous - See: Syphilis, skin;
    • dacryocystitis (late) - A52.71 Late syphilitic oculopathy
    • degeneration, spinal cord - A52.12 Other cerebrospinal syphilis
    • dementia paralytica - A52.17 General paresis
      • juvenilis - A50.45 Juvenile general paresis
    • destruction of bone - A52.77 Syphilis of bone and joint
    • dilatation, aorta - A52.01 Syphilitic aneurysm of aorta
    • due to blood transfusion - A53.9 Syphilis, unspecified
    • dura mater - A52.13 Late syphilitic meningitis
    • ear - A52.79 Other symptomatic late syphilis
      • inner - A52.79 Other symptomatic late syphilis
        • nerve (eighth) - A52.15 Late syphilitic neuropathy
        • neurorecurrence - A52.15 Late syphilitic neuropathy
    • early - A51.9 Early syphilis, unspecified
      • cardiovascular - A52.00 Cardiovascular syphilis, unspecified
      • central nervous system - A52.3 Neurosyphilis, unspecified
      • latent (without manifestations) (less than 2 years after infection) - A51.5 Early syphilis, latent
        • negative spinal fluid test - A51.5 Early syphilis, latent
        • serological relapse after treatment - A51.5 Early syphilis, latent
        • serology positive - A51.5 Early syphilis, latent
      • relapse (treated, untreated) - A51.9 Early syphilis, unspecified
      • skin - A51.39 Other secondary syphilis of skin
      • symptomatic - A51.9 Early syphilis, unspecified
        • extragenital chancre - A51.2 Primary syphilis of other sites
        • primary, except extragenital chancre - A51.0 Primary genital syphilis
        • secondary - See Also: Syphilis, secondary; - A51.39 Other secondary syphilis of skin
          • relapse (treated, untreated) - A51.49 Other secondary syphilitic conditions
      • ulcer - A51.39 Other secondary syphilis of skin
    • eighth nerve (neuritis) - A52.15 Late syphilitic neuropathy
    • endemic - A65 Nonvenereal syphilis
    • endocarditis - A52.03 Syphilitic endocarditis
      • aortic - A52.03 Syphilitic endocarditis
      • pulmonary - A52.03 Syphilitic endocarditis
    • epididymis (late) - A52.76 Other genitourinary symptomatic late syphilis
    • epiglottis (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • epiphysitis (congenital) (early) - A50.02 Early congenital syphilitic osteochondropathy
    • episcleritis (late) - A52.71 Late syphilitic oculopathy
    • esophagus - A52.79 Other symptomatic late syphilis
    • eustachian tube - A52.73 Symptomatic late syphilis of other respiratory organs
    • exposure to - Z20.2 Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission
    • eye - A52.71 Late syphilitic oculopathy
    • eyelid (late) (with gumma) - A52.71 Late syphilitic oculopathy
    • fallopian tube (late) - A52.76 Other genitourinary symptomatic late syphilis
    • fracture - A52.77 Syphilis of bone and joint
    • gallbladder (late) - A52.74 Syphilis of liver and other viscera
    • gastric (polyposis) (late) - A52.74 Syphilis of liver and other viscera
    • general - A53.9 Syphilis, unspecified
      • paralysis - A52.17 General paresis
        • juvenile - A50.45 Juvenile general paresis
    • genital (primary) - A51.0 Primary genital syphilis
    • glaucoma - A52.71 Late syphilitic oculopathy
    • gumma NEC - A52.79 Other symptomatic late syphilis
      • cardiovascular system - A52.00 Cardiovascular syphilis, unspecified
      • central nervous system - A52.3 Neurosyphilis, unspecified
      • congenital - A50.59 Other late congenital syphilis, symptomatic
    • heart (block) (decompensation) (disease) (failure) - A52.06 Other syphilitic heart involvement
      • valve NEC - A52.03 Syphilitic endocarditis
    • hemianesthesia - A52.19 Other symptomatic neurosyphilis
    • hemianopsia - A52.71 Late syphilitic oculopathy
    • hemiparesis - A52.17 General paresis
    • hemiplegia - A52.17 General paresis
    • hepatic artery - A52.09 Other cardiovascular syphilis
    • hepatis - A52.74 Syphilis of liver and other viscera
    • hepatomegaly, congenital - A50.08 Early visceral congenital syphilis
    • hereditaria tarda - See: Syphilis, congenital, late;
    • hereditary - See: Syphilis, congenital;
    • Hutchinson's teeth - A50.52 Hutchinson's teeth
    • hyalitis - A52.71 Late syphilitic oculopathy
    • inactive - See: Syphilis, latent;
    • infantum - See: Syphilis, congenital;
    • inherited - See: Syphilis, congenital;
    • internal ear - A52.79 Other symptomatic late syphilis
    • intestine (late) - A52.74 Syphilis of liver and other viscera
    • iris, iritis (secondary) - A51.43 Secondary syphilitic oculopathy
      • late - A52.71 Late syphilitic oculopathy
    • joint (late) - A52.77 Syphilis of bone and joint
    • keratitis (congenital) (interstitial) (late) - A50.31 Late congenital syphilitic interstitial keratitis
    • kidney (late) - A52.75 Syphilis of kidney and ureter
    • lacrimal passages (late) - A52.71 Late syphilitic oculopathy
    • larynx (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • late - A52.9 Late syphilis, unspecified
      • cardiovascular - A52.00 Cardiovascular syphilis, unspecified
      • central nervous system - A52.3 Neurosyphilis, unspecified
      • kidney - A52.75 Syphilis of kidney and ureter
      • latent or 2 years or more after infection (without manifestations) - A52.8 Late syphilis, latent
        • negative spinal fluid test - A52.8 Late syphilis, latent
        • serology positive - A52.8 Late syphilis, latent
      • paresis - A52.17 General paresis
      • specified site NEC - A52.79 Other symptomatic late syphilis
      • symptomatic or with manifestations - A52.79 Other symptomatic late syphilis
      • tabes - A52.11 Tabes dorsalis
    • latent - A53.0 Latent syphilis, unspecified as early or late
      • central nervous system - A52.2 Asymptomatic neurosyphilis
      • date of infection unspecified - A53.0 Latent syphilis, unspecified as early or late
      • early, or less than 2 years after infection - A51.5 Early syphilis, latent
      • follow-up of latent syphilis - A53.0 Latent syphilis, unspecified as early or late
        • date of infection unspecified - A53.0 Latent syphilis, unspecified as early or late
        • late, or 2 years or more after infection - A52.8 Late syphilis, latent
      • late, or 2 years or more after infection - A52.8 Late syphilis, latent
      • positive serology (only finding) - A53.0 Latent syphilis, unspecified as early or late
        • date of infection unspecified - A53.0 Latent syphilis, unspecified as early or late
        • early, or less than 2 years after infection - A51.5 Early syphilis, latent
        • late, or 2 years or more after infection - A52.8 Late syphilis, latent
      • with signs or symptoms - code by site and stage under Syphilis
    • lens (late) - A52.71 Late syphilitic oculopathy
    • leukoderma - A51.39 Other secondary syphilis of skin
      • late - A52.79 Other symptomatic late syphilis
    • lienitis - A52.79 Other symptomatic late syphilis
    • lip - A51.39 Other secondary syphilis of skin
      • chancre (primary) - A51.2 Primary syphilis of other sites
      • late - A52.79 Other symptomatic late syphilis
    • Lissauer's paralysis - A52.17 General paresis
    • liver - A52.74 Syphilis of liver and other viscera
    • locomotor ataxia - A52.11 Tabes dorsalis
    • lung - A52.72 Syphilis of lung and bronchus
    • lymph gland (early) (secondary) - A51.49 Other secondary syphilitic conditions
      • late - A52.79 Other symptomatic late syphilis
    • lymphadenitis (secondary) - A51.49 Other secondary syphilitic conditions
    • macular atrophy of skin - A51.39 Other secondary syphilis of skin
      • striated - A52.79 Other symptomatic late syphilis
    • mediastinum (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • meninges (adhesive) (brain) (spinal cord) - A52.13 Late syphilitic meningitis
    • meningitis - A52.13 Late syphilitic meningitis
      • acute (secondary) - A51.41 Secondary syphilitic meningitis
      • congenital - A50.41 Late congenital syphilitic meningitis
    • meningoencephalitis - A52.14 Late syphilitic encephalitis
    • meningovascular - A52.13 Late syphilitic meningitis
      • congenital - A50.41 Late congenital syphilitic meningitis
    • mesarteritis - A52.09 Other cardiovascular syphilis
      • brain - A52.04 Syphilitic cerebral arteritis
    • middle ear - A52.77 Syphilis of bone and joint
    • mitral stenosis - A52.03 Syphilitic endocarditis
    • monoplegia - A52.17 General paresis
    • mouth (secondary) - A51.39 Other secondary syphilis of skin
      • late - A52.79 Other symptomatic late syphilis
    • mucocutaneous (secondary) - A51.39 Other secondary syphilis of skin
      • late - A52.79 Other symptomatic late syphilis
    • mucous
      • membrane (secondary) - A51.39 Other secondary syphilis of skin
        • late - A52.79 Other symptomatic late syphilis
      • patches - A51.39 Other secondary syphilis of skin
        • congenital - A50.07 Early mucocutaneous congenital syphilis
    • mulberry molars - A50.52 Hutchinson's teeth
    • muscle - A52.78 Syphilis of other musculoskeletal tissue
    • myocardium - A52.06 Other syphilitic heart involvement
    • nasal sinus (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • neonatorum - See: Syphilis, congenital;
    • nephrotic syndrome (secondary) - A51.44 Secondary syphilitic nephritis
    • nerve palsy (any cranial nerve) - A52.15 Late syphilitic neuropathy
      • multiple - A52.15 Late syphilitic neuropathy
    • nervous system, central - A52.3 Neurosyphilis, unspecified
    • neuritis - A52.15 Late syphilitic neuropathy
      • acoustic - A52.15 Late syphilitic neuropathy
    • neurorecidive of retina - A52.19 Other symptomatic neurosyphilis
    • neuroretinitis - A52.19 Other symptomatic neurosyphilis
    • newborn - See: Syphilis, congenital;
    • nodular superficial (late) - A52.79 Other symptomatic late syphilis
    • nonvenereal - A65 Nonvenereal syphilis
    • nose (late) - A52.73 Symptomatic late syphilis of other respiratory organs
      • saddle back deformity - A50.57 Syphilitic saddle nose
    • occlusive arterial disease - A52.09 Other cardiovascular syphilis
    • oculopathy - A52.71 Late syphilitic oculopathy
    • ophthalmic (late) - A52.71 Late syphilitic oculopathy
    • optic nerve (atrophy) (neuritis) (papilla) - A52.15 Late syphilitic neuropathy
    • orbit (late) - A52.71 Late syphilitic oculopathy
    • organic - A53.9 Syphilis, unspecified
    • osseous (late) - A52.77 Syphilis of bone and joint
    • osteochondritis (congenital) (early) - A50.02 Early congenital syphilitic osteochondropathy
    • osteoporosis - A52.77 Syphilis of bone and joint
    • ovary (late) - A52.76 Other genitourinary symptomatic late syphilis
    • oviduct (late) - A52.76 Other genitourinary symptomatic late syphilis
    • palate (late) - A52.79 Other symptomatic late syphilis
    • pancreas (late) - A52.74 Syphilis of liver and other viscera
    • paralysis - A52.17 General paresis
      • general - A52.17 General paresis
        • juvenile - A50.45 Juvenile general paresis
    • paresis (general) - A52.17 General paresis
      • juvenile - A50.45 Juvenile general paresis
    • paresthesia - A52.19 Other symptomatic neurosyphilis
    • Parkinson's disease or syndrome - A52.19 Other symptomatic neurosyphilis
    • paroxysmal tachycardia - A52.06 Other syphilitic heart involvement
    • pemphigus (congenital) - A50.06 Early cutaneous congenital syphilis
    • penis (chancre) - A51.0 Primary genital syphilis
      • late - A52.76 Other genitourinary symptomatic late syphilis
    • pericardium - A52.06 Other syphilitic heart involvement
    • perichondritis, larynx (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • periosteum (late) - A52.77 Syphilis of bone and joint
      • congenital (early) - A50.02 Early congenital syphilitic osteochondropathy
      • early (secondary) - A51.46 Secondary syphilitic osteopathy
    • peripheral nerve - A52.79 Other symptomatic late syphilis
    • petrous bone (late) - A52.77 Syphilis of bone and joint
    • pharynx (late) - A52.73 Symptomatic late syphilis of other respiratory organs
      • secondary - A51.39 Other secondary syphilis of skin
    • pituitary (gland) - A52.79 Other symptomatic late syphilis
    • pleura (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • pneumonia, white - A50.04 Early congenital syphilitic pneumonia
    • pontine lesion - A52.17 General paresis
    • portal vein - A52.09 Other cardiovascular syphilis
    • primary - A51.0 Primary genital syphilis
      • anal - A51.1 Primary anal syphilis
      • and secondary - See: Syphilis, secondary;
      • central nervous system - A52.3 Neurosyphilis, unspecified
      • extragenital chancre NEC - A51.2 Primary syphilis of other sites
      • fingers - A51.2 Primary syphilis of other sites
      • genital - A51.0 Primary genital syphilis
      • lip - A51.2 Primary syphilis of other sites
      • specified site NEC - A51.2 Primary syphilis of other sites
      • tonsils - A51.2 Primary syphilis of other sites
    • prostate (late) - A52.76 Other genitourinary symptomatic late syphilis
    • ptosis (eyelid) - A52.71 Late syphilitic oculopathy
    • pulmonary (late) - A52.72 Syphilis of lung and bronchus
      • artery - A52.09 Other cardiovascular syphilis
    • pyelonephritis (late) - A52.75 Syphilis of kidney and ureter
    • recently acquired, symptomatic - A51.9 Early syphilis, unspecified
    • rectum (late) - A52.74 Syphilis of liver and other viscera
    • respiratory tract (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • retina, late - A52.71 Late syphilitic oculopathy
    • retrobulbar neuritis - A52.15 Late syphilitic neuropathy
    • salpingitis - A52.76 Other genitourinary symptomatic late syphilis
    • sclera (late) - A52.71 Late syphilitic oculopathy
    • sclerosis
      • cerebral - A52.17 General paresis
      • coronary - A52.06 Other syphilitic heart involvement
      • multiple - A52.11 Tabes dorsalis
    • scotoma (central) - A52.71 Late syphilitic oculopathy
    • scrotum (late) - A52.76 Other genitourinary symptomatic late syphilis
    • secondary (and primary) - A51.49 Other secondary syphilitic conditions
      • adenopathy - A51.49 Other secondary syphilitic conditions
      • anus - A51.39 Other secondary syphilis of skin
      • bone - A51.46 Secondary syphilitic osteopathy
      • chorioretinitis, choroiditis - A51.43 Secondary syphilitic oculopathy
      • hepatitis - A51.45 Secondary syphilitic hepatitis
      • liver - A51.45 Secondary syphilitic hepatitis
      • lymphadenitis - A51.49 Other secondary syphilitic conditions
      • meningitis (acute) - A51.41 Secondary syphilitic meningitis
      • mouth - A51.39 Other secondary syphilis of skin
      • mucous membranes - A51.39 Other secondary syphilis of skin
      • periosteum, periostitis - A51.46 Secondary syphilitic osteopathy
      • pharynx - A51.39 Other secondary syphilis of skin
      • relapse (treated, untreated) - A51.49 Other secondary syphilitic conditions
      • skin - A51.39 Other secondary syphilis of skin
      • specified form NEC - A51.49 Other secondary syphilitic conditions
      • tonsil - A51.39 Other secondary syphilis of skin
      • ulcer - A51.39 Other secondary syphilis of skin
      • viscera NEC - A51.49 Other secondary syphilitic conditions
      • vulva - A51.39 Other secondary syphilis of skin
    • seminal vesicle (late) - A52.76 Other genitourinary symptomatic late syphilis
    • seronegative with signs or symptoms - code by site and stage under Syphilis
    • seropositive
      • follow-up of latent syphilis - See: Syphilis, latent;
      • only finding - See: Syphilis, latent;
      • with signs or symptoms - code by site and stage under Syphilis
    • seventh nerve (paralysis) - A52.15 Late syphilitic neuropathy
    • sinus, sinusitis (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • skeletal system - A52.77 Syphilis of bone and joint
    • skin (with ulceration) (early) (secondary) - A51.39 Other secondary syphilis of skin
      • late or tertiary - A52.79 Other symptomatic late syphilis
    • small intestine - A52.74 Syphilis of liver and other viscera
    • spastic spinal paralysis - A52.17 General paresis
    • spermatic cord (late) - A52.76 Other genitourinary symptomatic late syphilis
    • spinal (cord) - A52.12 Other cerebrospinal syphilis
    • spleen - A52.79 Other symptomatic late syphilis
    • splenomegaly - A52.79 Other symptomatic late syphilis
    • spondylitis - A52.77 Syphilis of bone and joint
    • staphyloma - A52.71 Late syphilitic oculopathy
    • stigmata (congenital) - A50.59 Other late congenital syphilis, symptomatic
    • stomach - A52.74 Syphilis of liver and other viscera
    • synovium - A52.78 Syphilis of other musculoskeletal tissue
    • tabes dorsalis (late) - A52.11 Tabes dorsalis
      • juvenile - A50.45 Juvenile general paresis
    • tabetic type - A52.11 Tabes dorsalis
      • juvenile - A50.45 Juvenile general paresis
    • taboparesis - A52.17 General paresis
      • juvenile - A50.45 Juvenile general paresis
    • tachycardia - A52.06 Other syphilitic heart involvement
    • tendon (late) - A52.78 Syphilis of other musculoskeletal tissue
    • tertiary - A52.9 Late syphilis, unspecified
      • cardiovascular - A52.00 Cardiovascular syphilis, unspecified
      • central nervous system - A52.3 Neurosyphilis, unspecified
      • multiple NEC - A52.79 Other symptomatic late syphilis
      • specified site NEC - A52.79 Other symptomatic late syphilis
      • with symptoms NEC - A52.79 Other symptomatic late syphilis
    • testis - A52.76 Other genitourinary symptomatic late syphilis
    • thorax - A52.73 Symptomatic late syphilis of other respiratory organs
    • throat - A52.73 Symptomatic late syphilis of other respiratory organs
    • thymus (gland) (late) - A52.79 Other symptomatic late syphilis
    • thyroid (late) - A52.79 Other symptomatic late syphilis
    • tongue (late) - A52.79 Other symptomatic late syphilis
    • tonsil (lingual) (late) - A52.73 Symptomatic late syphilis of other respiratory organs
      • primary - A51.2 Primary syphilis of other sites
      • secondary - A51.39 Other secondary syphilis of skin
    • trachea (late) - A52.73 Symptomatic late syphilis of other respiratory organs
    • tunica vaginalis (late) - A52.76 Other genitourinary symptomatic late syphilis
    • ulcer (any site) (early) (secondary) - A51.39 Other secondary syphilis of skin
      • late - A52.79 Other symptomatic late syphilis
      • perforating - A52.79 Other symptomatic late syphilis
    • urethra (late) - A52.76 Other genitourinary symptomatic late syphilis
    • urogenital (late) - A52.76 Other genitourinary symptomatic late syphilis
    • uterus (late) - A52.76 Other genitourinary symptomatic late syphilis
    • uveal tract (secondary) - A51.43 Secondary syphilitic oculopathy
      • late - A52.71 Late syphilitic oculopathy
    • uveitis (secondary) - A51.43 Secondary syphilitic oculopathy
      • late - A52.71 Late syphilitic oculopathy
    • uvula (late) (perforated) - A52.79 Other symptomatic late syphilis
    • vagina - A51.0 Primary genital syphilis
      • late - A52.76 Other genitourinary symptomatic late syphilis
    • valvulitis NEC - A52.03 Syphilitic endocarditis
    • vascular - A52.00 Cardiovascular syphilis, unspecified
      • brain (cerebral) - A52.05 Other cerebrovascular syphilis
    • ventriculi - A52.74 Syphilis of liver and other viscera
    • vesicae urinariae (late) - A52.76 Other genitourinary symptomatic late syphilis
    • viscera (abdominal) (late) - A52.74 Syphilis of liver and other viscera
      • secondary - A51.49 Other secondary syphilitic conditions
    • vitreous (opacities) (late) - A52.71 Late syphilitic oculopathy
      • hemorrhage - A52.71 Late syphilitic oculopathy
    • vulva - A51.0 Primary genital syphilis
      • late - A52.76 Other genitourinary symptomatic late syphilis
      • secondary - A51.39 Other secondary syphilis of skin

Clinical Terms

The following are some of the clinical term definitions related or applicable to syphilis, syphilitic (acquired) within the ICD-10 index for Diseases and Injuries.

Acoustics: The branch of physics that deals with sound and sound waves. In medicine it is often applied in procedures in speech and hearing studies. With regard to the environment, it refers to the characteristics of a room, auditorium, theatre, building, etc. that determines the audibility or fidelity of sounds in it. (From Random House Unabridged Dictionary, 2d ed)

Lymphadenopathy: Disease of LYMPH NODES which are abnormal in size, number or consistency.

Aneurysm: Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.

Arteries: The vessels carrying blood away from the heart.

Joint Diseases: Diseases involving the JOINTS.

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

Bulbar Palsy, Progressive: A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)

Cardiovascular System: The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.

Central Nervous System: The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.

Chorioretinitis: Inflammation of the choroid in which the sensory retina becomes edematous and opaque. The inflammatory cells and exudate may burst through the sensory retina to cloud the vitreous body.

Choroiditis: Inflammation of the choroid.

Cranial Nerves: Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.

Dura Mater: The outermost of the three MENINGES, a fibrous membrane of connective tissue that covers the brain and the spinal cord.

Ear: The hearing and equilibrium system of the body. It consists of three parts: the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR. Sound waves are transmitted through this organ where vibration is transduced to nerve signals that pass through the ACOUSTIC NERVE to the CENTRAL NERVOUS SYSTEM. The inner ear also contains the vestibular organ that maintains equilibrium by transducing signals to the VESTIBULAR NERVE.

Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.

Esophagus: The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.

Eustachian Tube: A narrow passageway that connects the upper part of the throat to the TYMPANIC CAVITY.

Eye: The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.

Fingers: Four or five slender jointed digits in humans and primates, attached to each HAND.

Foot: The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.

Neurosyphilis: Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)

Genitalia: The external and internal organs involved in the functions of REPRODUCTION.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Hemianopsia: Partial or complete loss of vision in one half of the visual field(s) of one or both eyes. Subtypes include altitudinal hemianopsia, characterized by a visual defect above or below the horizontal meridian of the visual field. Homonymous hemianopsia refers to a visual defect that affects both eyes equally, and occurs either to the left or right of the midline of the visual field. Binasal hemianopsia consists of loss of vision in the nasal hemifields of both eyes. Bitemporal hemianopsia is the bilateral loss of vision in the temporal fields. Quadrantanopsia refers to loss of vision in one quarter of the visual field in one or both eyes.

Hemiplegia: Severe or complete loss of motor function on one side of the body. This condition is usually caused by BRAIN DISEASES that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, BRAIN STEM lesions; cervical SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; and other conditions may manifest as hemiplegia. The term hemiparesis (see PARESIS) refers to mild to moderate weakness involving one side of the body.

Hemorrhage: Bleeding or escape of blood from a vessel.

Hepatitis: INFLAMMATION of the LIVER.

Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.

Lip: Either of the two fleshy, full-blooded margins of the mouth.

Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.

Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.

Lymphadenitis: Inflammation of the lymph nodes.

Meningitis: Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)

Meningoencephalitis: An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions.

Ear, Middle: The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat.

Mouth: The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.

Mucous Membrane: An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.

Muscles: Contractile tissue that produces movement in animals.

Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.

Neuritis: A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.

Infant, Newborn: An infant during the first 28 days after birth.

Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)

Paresis: A general term referring to a mild to moderate degree of muscular weakness, occasionally used as a synonym for PARALYSIS (severe or complete loss of motor function). In the older literature, paresis often referred specifically to paretic neurosyphilis (see NEUROSYPHILIS). "General paresis" and "general paralysis" may still carry that connotation. Bilateral lower extremity paresis is referred to as PARAPARESIS.

Paresthesia: Subjective cutaneous sensations (e.g., cold, warmth, tingling, pressure, etc.) that are experienced spontaneously in the absence of stimulation.

Pericardium: A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.

Peripheral Nerves: The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.

Pharyngitis: Inflammation of the throat (PHARYNX).

Pharynx: A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx).

Pneumonia: Infection of the lung often accompanied by inflammation.

Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.

Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.

Salpingitis: Inflammation of the uterine salpinx, the trumpet-shaped FALLOPIAN TUBES, usually caused by ascending infections of organisms from the lower reproductive tract. Salpingitis can lead to tubal scarring, hydrosalpinx, tubal occlusion, INFERTILITY, and ectopic pregnancy (PREGNANCY, ECTOPIC)

Sclerosis: A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.

Skin: The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

Intestine, Small: The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.

Spleen: An encapsulated lymphatic organ through which venous blood filters.

Splenomegaly: Enlargement of the spleen.

Spondylitis: Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions.

Stomach: An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Testis: The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.

Thorax: The upper part of the trunk between the NECK and the ABDOMEN. It contains the chief organs of the circulatory and respiratory systems. (From Stedman, 25th ed)

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Palatine Tonsil: A round-to-oval mass of lymphoid tissue embedded in the lateral wall of the PHARYNX. There is one on each side of the oropharynx in the fauces between the anterior and posterior pillars of the SOFT PALATE.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Vagina: The genital canal in the female, extending from the UTERUS to the VULVA. (Stedman, 25th ed)

Vulva: The external genitalia of the female. It includes the CLITORIS, the labia, the vestibule, and its glands.