Syphilis, syphilitic (acquired) - in the ICD-10-CM Index
Annotation Back-References in the 2025 ICD-10-CM Index to Diseases and Injuries
Browse the ICD-10-CM codes with references applicable to the clinical term "syphilis, syphilitic (acquired)"
Syphilis, syphilitic (acquired) - A53.9 Syphilis, unspecified
abdomen (late) - A52.79 Other symptomatic late syphilis
acoustic nerve - A52.15 Late syphilitic neuropathy
adenopathy (secondary) - A51.49 Other secondary syphilitic conditions
adrenal (gland) (with cortical hypofunction) - A52.79 Other symptomatic late syphilis
age under 2 years NOS - See Also: Syphilis, congenital, early;
acquired - A51.9 Early syphilis, unspecified
alopecia (secondary) - A51.32 Syphilitic alopecia
anemia (late) - A52.79 Other symptomatic late syphilis
aneurysm (aorta) (ruptured) - A52.01 Syphilitic aneurysm of aorta
anus (late) - A52.74 Syphilis of liver and other viscera
aorta (arch) (abdominal) (thoracic) - A52.02 Syphilitic aortitis
aneurysm - A52.01 Syphilitic aneurysm of aorta
aortic (insufficiency) (regurgitation) (stenosis) - A52.03 Syphilitic endocarditis
aneurysm - A52.01 Syphilitic aneurysm of aorta
arachnoid (adhesive) (cerebral) (spinal) - A52.13 Late syphilitic meningitis
asymptomatic - See: Syphilis, latent;
ataxia (locomotor) - A52.11 Tabes dorsalis
atrophoderma maculatum - A51.39 Other secondary syphilis of skin
auricular fibrillation - A52.06 Other syphilitic heart involvement
bladder (late) - A52.76 Other genitourinary symptomatic late syphilis
bone - A52.77 Syphilis of bone and joint
secondary - A51.46 Secondary syphilitic osteopathy
brain - A52.17 General paresis
breast (late) - A52.79 Other symptomatic late syphilis
bronchus (late) - A52.72 Syphilis of lung and bronchus
bubo (primary) - A51.0 Primary genital syphilis
bulbar palsy - A52.19 Other symptomatic neurosyphilis
bursa (late) - A52.78 Syphilis of other musculoskeletal tissue
cardiac decompensation - A52.06 Other syphilitic heart involvement
cardiovascular - A52.00 Cardiovascular syphilis, unspecified
central nervous system (late) (recurrent) (relapse) (tertiary) - A52.3 Neurosyphilis, unspecified
aneurysm - A52.05 Other cerebrovascular syphilis
congenital - A50.40 Late congenital neurosyphilis, unspecified
juvenile - A50.40 Late congenital neurosyphilis, unspecified
remission in (sustained) - A52.3 Neurosyphilis, unspecified
serology doubtful, negative, or positive - A52.3 Neurosyphilis, unspecified
specified nature or site NEC - A52.19 Other symptomatic neurosyphilis
vascular - A52.05 Other cerebrovascular syphilis
with
ataxia - A52.11 Tabes dorsalis
general paralysis - A52.17 General paresis
juvenile - A50.45 Juvenile general paresis
paresis (general) - A52.17 General paresis
juvenile - A50.45 Juvenile general paresis
tabes (dorsalis) - A52.11 Tabes dorsalis
juvenile - A50.45 Juvenile general paresis
taboparesis - A52.17 General paresis
juvenile - A50.45 Juvenile general paresis
cerebral - A52.17 General paresis
cerebrospinal (tabetic type) - A52.12 Other cerebrospinal syphilis
cerebrovascular - A52.05 Other cerebrovascular syphilis
cervix (late) - A52.76 Other genitourinary symptomatic late syphilis
chancre (multiple) - A51.0 Primary genital syphilis
Charcot's joint - A52.16 Charcot's arthropathy (tabetic)
chorioretinitis - A51.43 Secondary syphilitic oculopathy
choroiditis - See: Syphilitic chorioretinitis;
choroidoretinitis - See: Syphilitic chorioretinitis;
ciliary body (secondary) - A51.43 Secondary syphilitic oculopathy
late - A52.71 Late syphilitic oculopathy
colon (late) - A52.74 Syphilis of liver and other viscera
combined spinal sclerosis - A52.11 Tabes dorsalis
condyloma (latum) - A51.31 Condyloma latum
congenital - A50.9 Congenital syphilis, unspecified
chorioretinitis, choroiditis - A50.01 Early congenital syphilitic oculopathy
early, or less than 2 years after birth NEC - A50.2 Early congenital syphilis, unspecified
latent (without manifestations) - A50.1 Early congenital syphilis, latent
symptomatic - A50.09 Other early congenital syphilis, symptomatic
cutaneous - A50.06 Early cutaneous congenital syphilis
mucocutaneous - A50.07 Early mucocutaneous congenital syphilis
oculopathy - A50.01 Early congenital syphilitic oculopathy
osteochondropathy - A50.02 Early congenital syphilitic osteochondropathy
pharyngitis - A50.03 Early congenital syphilitic pharyngitis
pneumonia - A50.04 Early congenital syphilitic pneumonia
rhinitis - A50.05 Early congenital syphilitic rhinitis
visceral - A50.08 Early visceral congenital syphilis
with manifestations - See: Syphilis, congenital, early, symptomatic;
interstitial keratitis - A50.31 Late congenital syphilitic interstitial keratitis
juvenile neurosyphilis - A50.45 Juvenile general paresis
late, or 2 years or more after birth NEC - A50.7 Late congenital syphilis, unspecified
chorioretinitis, choroiditis - A50.32 Late congenital syphilitic chorioretinitis
interstitial keratitis - A50.31 Late congenital syphilitic interstitial keratitis
juvenile neurosyphilis - A50.45 Juvenile general paresis
latent (without manifestations) - A50.6 Late congenital syphilis, latent
symptomatic or with manifestations NEC - A50.59 Other late congenital syphilis, symptomatic
arthropathy - A50.55 Late congenital syphilitic arthropathy
cardiovascular - A50.54 Late congenital cardiovascular syphilis
Clutton's joints - A50.51 Clutton's joints
Hutchinson's teeth - A50.52 Hutchinson's teeth
Hutchinson's triad - A50.53 Hutchinson's triad
osteochondropathy - A50.56 Late congenital syphilitic osteochondropathy
saddle nose - A50.57 Syphilitic saddle nose
with
conjugal - A53.9 Syphilis, unspecified
tabes - A52.11 Tabes dorsalis
conjunctiva (late) - A52.71 Late syphilitic oculopathy
contact - Z20.2 Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission
cord bladder - A52.19 Other symptomatic neurosyphilis
cornea, late - A52.71 Late syphilitic oculopathy
coronary (artery) (sclerosis) - A52.06 Other syphilitic heart involvement
coryza, congenital - A50.05 Early congenital syphilitic rhinitis
cranial nerve - A52.15 Late syphilitic neuropathy
multiple palsies - A52.15 Late syphilitic neuropathy
cutaneous - See: Syphilis, skin;
dacryocystitis (late) - A52.71 Late syphilitic oculopathy
degeneration, spinal cord - A52.12 Other cerebrospinal syphilis
dementia paralytica - A52.17 General paresis
juvenilis - A50.45 Juvenile general paresis
destruction of bone - A52.77 Syphilis of bone and joint
dilatation, aorta - A52.01 Syphilitic aneurysm of aorta
due to blood transfusion - A53.9 Syphilis, unspecified
dura mater - A52.13 Late syphilitic meningitis
ear - A52.79 Other symptomatic late syphilis
early - A51.9 Early syphilis, unspecified
cardiovascular - A52.00 Cardiovascular syphilis, unspecified
central nervous system - A52.3 Neurosyphilis, unspecified
latent (without manifestations) (less than 2 years after infection) - A51.5 Early syphilis, latent
relapse (treated, untreated) - A51.9 Early syphilis, unspecified
skin - A51.39 Other secondary syphilis of skin
symptomatic - A51.9 Early syphilis, unspecified
ulcer - A51.39 Other secondary syphilis of skin
eighth nerve (neuritis) - A52.15 Late syphilitic neuropathy
endemic - A65 Nonvenereal syphilis
endocarditis - A52.03 Syphilitic endocarditis
epididymis (late) - A52.76 Other genitourinary symptomatic late syphilis
epiglottis (late) - A52.73 Symptomatic late syphilis of other respiratory organs
epiphysitis (congenital) (early) - A50.02 Early congenital syphilitic osteochondropathy
episcleritis (late) - A52.71 Late syphilitic oculopathy
esophagus - A52.79 Other symptomatic late syphilis
eustachian tube - A52.73 Symptomatic late syphilis of other respiratory organs
exposure to - Z20.2 Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission
eye - A52.71 Late syphilitic oculopathy
eyelid (late) (with gumma) - A52.71 Late syphilitic oculopathy
fallopian tube (late) - A52.76 Other genitourinary symptomatic late syphilis
fracture - A52.77 Syphilis of bone and joint
gallbladder (late) - A52.74 Syphilis of liver and other viscera
gastric (polyposis) (late) - A52.74 Syphilis of liver and other viscera
general - A53.9 Syphilis, unspecified
genital (primary) - A51.0 Primary genital syphilis
glaucoma - A52.71 Late syphilitic oculopathy
gumma NEC - A52.79 Other symptomatic late syphilis
heart (block) (decompensation) (disease) (failure) - A52.06 Other syphilitic heart involvement
valve NEC - A52.03 Syphilitic endocarditis
hemianesthesia - A52.19 Other symptomatic neurosyphilis
hemianopsia - A52.71 Late syphilitic oculopathy
hemiparesis - A52.17 General paresis
hemiplegia - A52.17 General paresis
hepatic artery - A52.09 Other cardiovascular syphilis
hepatis - A52.74 Syphilis of liver and other viscera
hepatomegaly, congenital - A50.08 Early visceral congenital syphilis
hereditaria tarda - See: Syphilis, congenital, late;
hereditary - See: Syphilis, congenital;
Hutchinson's teeth - A50.52 Hutchinson's teeth
hyalitis - A52.71 Late syphilitic oculopathy
inactive - See: Syphilis, latent;
infantum - See: Syphilis, congenital;
inherited - See: Syphilis, congenital;
internal ear - A52.79 Other symptomatic late syphilis
intestine (late) - A52.74 Syphilis of liver and other viscera
iris, iritis (secondary) - A51.43 Secondary syphilitic oculopathy
late - A52.71 Late syphilitic oculopathy
joint (late) - A52.77 Syphilis of bone and joint
keratitis (congenital) (interstitial) (late) - A50.31 Late congenital syphilitic interstitial keratitis
kidney (late) - A52.75 Syphilis of kidney and ureter
lacrimal passages (late) - A52.71 Late syphilitic oculopathy
larynx (late) - A52.73 Symptomatic late syphilis of other respiratory organs
late - A52.9 Late syphilis, unspecified
cardiovascular - A52.00 Cardiovascular syphilis, unspecified
central nervous system - A52.3 Neurosyphilis, unspecified
kidney - A52.75 Syphilis of kidney and ureter
latent or 2 years or more after infection (without manifestations) - A52.8 Late syphilis, latent
paresis - A52.17 General paresis
specified site NEC - A52.79 Other symptomatic late syphilis
symptomatic or with manifestations - A52.79 Other symptomatic late syphilis
tabes - A52.11 Tabes dorsalis
latent - A53.0 Latent syphilis, unspecified as early or late
central nervous system - A52.2 Asymptomatic neurosyphilis
date of infection unspecified - A53.0 Latent syphilis, unspecified as early or late
early, or less than 2 years after infection - A51.5 Early syphilis, latent
follow-up of latent syphilis - A53.0 Latent syphilis, unspecified as early or late
late, or 2 years or more after infection - A52.8 Late syphilis, latent
positive serology (only finding) - A53.0 Latent syphilis, unspecified as early or late
with signs or symptoms - code by site and stage under Syphilis
lens (late) - A52.71 Late syphilitic oculopathy
leukoderma - A51.39 Other secondary syphilis of skin
late - A52.79 Other symptomatic late syphilis
lienitis - A52.79 Other symptomatic late syphilis
lip - A51.39 Other secondary syphilis of skin
Lissauer's paralysis - A52.17 General paresis
liver - A52.74 Syphilis of liver and other viscera
locomotor ataxia - A52.11 Tabes dorsalis
lung - A52.72 Syphilis of lung and bronchus
lymph gland (early) (secondary) - A51.49 Other secondary syphilitic conditions
late - A52.79 Other symptomatic late syphilis
lymphadenitis (secondary) - A51.49 Other secondary syphilitic conditions
macular atrophy of skin - A51.39 Other secondary syphilis of skin
striated - A52.79 Other symptomatic late syphilis
mediastinum (late) - A52.73 Symptomatic late syphilis of other respiratory organs
meninges (adhesive) (brain) (spinal cord) - A52.13 Late syphilitic meningitis
meningitis - A52.13 Late syphilitic meningitis
meningoencephalitis - A52.14 Late syphilitic encephalitis
meningovascular - A52.13 Late syphilitic meningitis
congenital - A50.41 Late congenital syphilitic meningitis
mesarteritis - A52.09 Other cardiovascular syphilis
brain - A52.04 Syphilitic cerebral arteritis
middle ear - A52.77 Syphilis of bone and joint
mitral stenosis - A52.03 Syphilitic endocarditis
monoplegia - A52.17 General paresis
mouth (secondary) - A51.39 Other secondary syphilis of skin
late - A52.79 Other symptomatic late syphilis
mucocutaneous (secondary) - A51.39 Other secondary syphilis of skin
late - A52.79 Other symptomatic late syphilis
mucous
mulberry molars - A50.52 Hutchinson's teeth
muscle - A52.78 Syphilis of other musculoskeletal tissue
myocardium - A52.06 Other syphilitic heart involvement
nasal sinus (late) - A52.73 Symptomatic late syphilis of other respiratory organs
neonatorum - See: Syphilis, congenital;
nephrotic syndrome (secondary) - A51.44 Secondary syphilitic nephritis
nerve palsy (any cranial nerve) - A52.15 Late syphilitic neuropathy
multiple - A52.15 Late syphilitic neuropathy
nervous system, central - A52.3 Neurosyphilis, unspecified
neuritis - A52.15 Late syphilitic neuropathy
acoustic - A52.15 Late syphilitic neuropathy
neurorecidive of retina - A52.19 Other symptomatic neurosyphilis
neuroretinitis - A52.19 Other symptomatic neurosyphilis
newborn - See: Syphilis, congenital;
nodular superficial (late) - A52.79 Other symptomatic late syphilis
nonvenereal - A65 Nonvenereal syphilis
nose (late) - A52.73 Symptomatic late syphilis of other respiratory organs
saddle back deformity - A50.57 Syphilitic saddle nose
occlusive arterial disease - A52.09 Other cardiovascular syphilis
oculopathy - A52.71 Late syphilitic oculopathy
ophthalmic (late) - A52.71 Late syphilitic oculopathy
optic nerve (atrophy) (neuritis) (papilla) - A52.15 Late syphilitic neuropathy
orbit (late) - A52.71 Late syphilitic oculopathy
organic - A53.9 Syphilis, unspecified
osseous (late) - A52.77 Syphilis of bone and joint
osteochondritis (congenital) (early) - A50.02 Early congenital syphilitic osteochondropathy
osteoporosis - A52.77 Syphilis of bone and joint
ovary (late) - A52.76 Other genitourinary symptomatic late syphilis
oviduct (late) - A52.76 Other genitourinary symptomatic late syphilis
palate (late) - A52.79 Other symptomatic late syphilis
pancreas (late) - A52.74 Syphilis of liver and other viscera
paralysis - A52.17 General paresis
paresis (general) - A52.17 General paresis
juvenile - A50.45 Juvenile general paresis
paresthesia - A52.19 Other symptomatic neurosyphilis
Parkinson's disease or syndrome - A52.19 Other symptomatic neurosyphilis
paroxysmal tachycardia - A52.06 Other syphilitic heart involvement
pemphigus (congenital) - A50.06 Early cutaneous congenital syphilis
penis (chancre) - A51.0 Primary genital syphilis
late - A52.76 Other genitourinary symptomatic late syphilis
pericardium - A52.06 Other syphilitic heart involvement
perichondritis, larynx (late) - A52.73 Symptomatic late syphilis of other respiratory organs
periosteum (late) - A52.77 Syphilis of bone and joint
peripheral nerve - A52.79 Other symptomatic late syphilis
petrous bone (late) - A52.77 Syphilis of bone and joint
pharynx (late) - A52.73 Symptomatic late syphilis of other respiratory organs
secondary - A51.39 Other secondary syphilis of skin
pituitary (gland) - A52.79 Other symptomatic late syphilis
pleura (late) - A52.73 Symptomatic late syphilis of other respiratory organs
pneumonia, white - A50.04 Early congenital syphilitic pneumonia
pontine lesion - A52.17 General paresis
portal vein - A52.09 Other cardiovascular syphilis
primary - A51.0 Primary genital syphilis
anal - A51.1 Primary anal syphilis
and secondary - See: Syphilis, secondary;
central nervous system - A52.3 Neurosyphilis, unspecified
extragenital chancre NEC - A51.2 Primary syphilis of other sites
fingers - A51.2 Primary syphilis of other sites
genital - A51.0 Primary genital syphilis
lip - A51.2 Primary syphilis of other sites
specified site NEC - A51.2 Primary syphilis of other sites
tonsils - A51.2 Primary syphilis of other sites
prostate (late) - A52.76 Other genitourinary symptomatic late syphilis
ptosis (eyelid) - A52.71 Late syphilitic oculopathy
pulmonary (late) - A52.72 Syphilis of lung and bronchus
artery - A52.09 Other cardiovascular syphilis
pyelonephritis (late) - A52.75 Syphilis of kidney and ureter
recently acquired, symptomatic - A51.9 Early syphilis, unspecified
rectum (late) - A52.74 Syphilis of liver and other viscera
respiratory tract (late) - A52.73 Symptomatic late syphilis of other respiratory organs
retina, late - A52.71 Late syphilitic oculopathy
retrobulbar neuritis - A52.15 Late syphilitic neuropathy
salpingitis - A52.76 Other genitourinary symptomatic late syphilis
sclera (late) - A52.71 Late syphilitic oculopathy
sclerosis
scotoma (central) - A52.71 Late syphilitic oculopathy
scrotum (late) - A52.76 Other genitourinary symptomatic late syphilis
secondary (and primary) - A51.49 Other secondary syphilitic conditions
adenopathy - A51.49 Other secondary syphilitic conditions
anus - A51.39 Other secondary syphilis of skin
bone - A51.46 Secondary syphilitic osteopathy
chorioretinitis, choroiditis - A51.43 Secondary syphilitic oculopathy
hepatitis - A51.45 Secondary syphilitic hepatitis
liver - A51.45 Secondary syphilitic hepatitis
lymphadenitis - A51.49 Other secondary syphilitic conditions
meningitis (acute) - A51.41 Secondary syphilitic meningitis
mouth - A51.39 Other secondary syphilis of skin
mucous membranes - A51.39 Other secondary syphilis of skin
periosteum, periostitis - A51.46 Secondary syphilitic osteopathy
pharynx - A51.39 Other secondary syphilis of skin
relapse (treated, untreated) - A51.49 Other secondary syphilitic conditions
skin - A51.39 Other secondary syphilis of skin
specified form NEC - A51.49 Other secondary syphilitic conditions
tonsil - A51.39 Other secondary syphilis of skin
ulcer - A51.39 Other secondary syphilis of skin
viscera NEC - A51.49 Other secondary syphilitic conditions
vulva - A51.39 Other secondary syphilis of skin
seminal vesicle (late) - A52.76 Other genitourinary symptomatic late syphilis
seronegative with signs or symptoms - code by site and stage under Syphilis
seropositive
follow-up of latent syphilis - See: Syphilis, latent;
only finding - See: Syphilis, latent;
with signs or symptoms - code by site and stage under Syphilis
seventh nerve (paralysis) - A52.15 Late syphilitic neuropathy
sinus, sinusitis (late) - A52.73 Symptomatic late syphilis of other respiratory organs
skeletal system - A52.77 Syphilis of bone and joint
skin (with ulceration) (early) (secondary) - A51.39 Other secondary syphilis of skin
late or tertiary - A52.79 Other symptomatic late syphilis
small intestine - A52.74 Syphilis of liver and other viscera
spastic spinal paralysis - A52.17 General paresis
spermatic cord (late) - A52.76 Other genitourinary symptomatic late syphilis
spinal (cord) - A52.12 Other cerebrospinal syphilis
spleen - A52.79 Other symptomatic late syphilis
splenomegaly - A52.79 Other symptomatic late syphilis
spondylitis - A52.77 Syphilis of bone and joint
staphyloma - A52.71 Late syphilitic oculopathy
stigmata (congenital) - A50.59 Other late congenital syphilis, symptomatic
stomach - A52.74 Syphilis of liver and other viscera
synovium - A52.78 Syphilis of other musculoskeletal tissue
tabes dorsalis (late) - A52.11 Tabes dorsalis
juvenile - A50.45 Juvenile general paresis
tabetic type - A52.11 Tabes dorsalis
juvenile - A50.45 Juvenile general paresis
taboparesis - A52.17 General paresis
juvenile - A50.45 Juvenile general paresis
tachycardia - A52.06 Other syphilitic heart involvement
tendon (late) - A52.78 Syphilis of other musculoskeletal tissue
tertiary - A52.9 Late syphilis, unspecified
testis - A52.76 Other genitourinary symptomatic late syphilis
thorax - A52.73 Symptomatic late syphilis of other respiratory organs
throat - A52.73 Symptomatic late syphilis of other respiratory organs
thymus (gland) (late) - A52.79 Other symptomatic late syphilis
thyroid (late) - A52.79 Other symptomatic late syphilis
tongue (late) - A52.79 Other symptomatic late syphilis
tonsil (lingual) (late) - A52.73 Symptomatic late syphilis of other respiratory organs
trachea (late) - A52.73 Symptomatic late syphilis of other respiratory organs
tunica vaginalis (late) - A52.76 Other genitourinary symptomatic late syphilis
ulcer (any site) (early) (secondary) - A51.39 Other secondary syphilis of skin
urethra (late) - A52.76 Other genitourinary symptomatic late syphilis
urogenital (late) - A52.76 Other genitourinary symptomatic late syphilis
uterus (late) - A52.76 Other genitourinary symptomatic late syphilis
uveal tract (secondary) - A51.43 Secondary syphilitic oculopathy
late - A52.71 Late syphilitic oculopathy
uveitis (secondary) - A51.43 Secondary syphilitic oculopathy
late - A52.71 Late syphilitic oculopathy
uvula (late) (perforated) - A52.79 Other symptomatic late syphilis
vagina - A51.0 Primary genital syphilis
late - A52.76 Other genitourinary symptomatic late syphilis
valvulitis NEC - A52.03 Syphilitic endocarditis
vascular - A52.00 Cardiovascular syphilis, unspecified
brain (cerebral) - A52.05 Other cerebrovascular syphilis
ventriculi - A52.74 Syphilis of liver and other viscera
vesicae urinariae (late) - A52.76 Other genitourinary symptomatic late syphilis
viscera (abdominal) (late) - A52.74 Syphilis of liver and other viscera
secondary - A51.49 Other secondary syphilitic conditions
vitreous (opacities) (late) - A52.71 Late syphilitic oculopathy
hemorrhage - A52.71 Late syphilitic oculopathy
vulva - A51.0 Primary genital syphilis
Applicable Clinical Terms Definitions
Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Bulbar Palsy, Progressive: A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)
Chorioretinitis: Inflammation of the choroid in which the sensory retina becomes edematous and opaque. The inflammatory cells and exudate may burst through the sensory retina to cloud the vitreous body.
Choroiditis: Inflammation of the choroid.
Cranial Nerves: Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.
Dura Mater: The outermost of the three MENINGES, a fibrous membrane of connective tissue that covers the brain and the spinal cord.
Ear: The hearing and equilibrium system of the body. It consists of three parts: the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR. Sound waves are transmitted through this organ where vibration is transduced to nerve signals that pass through the ACOUSTIC NERVE to the CENTRAL NERVOUS SYSTEM. The inner ear also contains the vestibular organ that maintains equilibrium by transducing signals to the VESTIBULAR NERVE.
Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.
Esophagus: The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
Eustachian Tube: A narrow passageway that connects the upper part of the throat to the TYMPANIC CAVITY.
Eye: The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
Hemianopsia: Partial or complete loss of vision in one half of the visual field(s) of one or both eyes. Subtypes include altitudinal hemianopsia, characterized by a visual defect above or below the horizontal meridian of the visual field. Homonymous hemianopsia refers to a visual defect that affects both eyes equally, and occurs either to the left or right of the midline of the visual field. Binasal hemianopsia consists of loss of vision in the nasal hemifields of both eyes. Bitemporal hemianopsia is the bilateral loss of vision in the temporal fields. Quadrantanopsia refers to loss of vision in one quarter of the visual field in one or both eyes.
Hemiplegia: Severe or complete loss of motor function on one side of the body. This condition is usually caused by BRAIN DISEASES that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, BRAIN STEM lesions; cervical SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; and other conditions may manifest as hemiplegia. The term hemiparesis (see PARESIS) refers to mild to moderate weakness involving one side of the body.
Hepatic Artery: A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.
Lip: Either of the two fleshy, full-blooded margins of the mouth.
Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Meningitis: Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)
Meningoencephalitis: An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions.
Ear, Middle: The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat.
Muscles: Contractile tissue that produces movement in animals.
Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Neuritis: A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.
Infant, Newborn: An infant during the first 28 days after birth.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
Paresthesia: Subjective cutaneous sensations (e.g., cold, warmth, tingling, pressure, etc.) that are experienced spontaneously in the absence of stimulation.
Pericardium: A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
Peripheral Nerves: The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.
Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
Salpingitis: Inflammation of the uterine salpinx, the trumpet-shaped FALLOPIAN TUBES, usually caused by ascending infections of organisms from the lower reproductive tract. Salpingitis can lead to tubal scarring, hydrosalpinx, tubal occlusion, INFERTILITY, and ectopic pregnancy (PREGNANCY, ECTOPIC)
Sclerosis: A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.
Intestine, Small: The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
Spleen: An encapsulated lymphatic organ through which venous blood filters.
Splenomegaly: Enlargement of the spleen.
Spondylitis: Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions.
Stomach: An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.
Testis: The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
Thorax: The upper part of the trunk between the NECK and the ABDOMEN. It contains the chief organs of the circulatory and respiratory systems. (From Stedman, 25th ed)
Vagina: The genital canal in the female, extending from the UTERUS to the VULVA. (Stedman, 25th ed)
Vulva: The external genitalia of the female. It includes the CLITORIS, the labia, the vestibule, and its glands.
