2024 ICD-10-CM Diagnosis Code A52.03

Syphilitic endocarditis

Short Description:
Syphilitic endocarditis
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator [1]
Code Navigator:

Code Classification

  • Certain infectious and parasitic diseases
    • Infections with a predominantly sexual mode of transmission
      • Late syphilis

A52.03 is a billable diagnosis code used to specify a medical diagnosis of syphilitic endocarditis. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Infective endocarditis of aortic valve
  • Infective endocarditis of mitral valve
  • Infective endocarditis of pulmonary valve
  • Inflammation of aortic valve
  • Late syphilitic pulmonary regurgitation
  • Syphilis of mitral valve
  • Syphilis of pulmonary valve
  • Syphilis of tricuspid valve
  • Syphilitic aortic stenosis
  • Syphilitic endocarditis
  • Syphilitic endocarditis of aortic valve
  • Syphilitic endocarditis of mitral valve
  • Syphilitic endocarditis of pulmonary valve
  • Syphilitic endocarditis of tricuspid valve
  • Syphilitic valve disease
  • Syphilitic valvular endocarditis

Clinical Classification

Clinical CategoryCCSR Category CodeInpatient Default CCSROutpatient Default CCSR
Endocarditis and endocardial diseaseCIR004N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis.N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis.
Sexually transmitted infections (excluding HIV and hepatitis)INF010Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Syphilitic aortic valve incompetence or stenosis
  • Syphilitic mitral valve stenosis
  • Syphilitic pulmonary valve regurgitation

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert to ICD-9-CM Code

Source ICD-10-CM CodeTarget ICD-9-CM Code
A52.03093.20 - Syphil endocarditis NOS
Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.
A52.03093.21 - Syphilitic mitral valve
Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.
A52.03093.22 - Syphilitic aortic valve
Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.
A52.03093.23 - Syphil tricuspid valve
Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.
A52.03093.24 - Syphil pulmonary valve
Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


What is endocarditis?

Endocarditis is sometimes called infective endocarditis. It's a rare, but life-threatening inflammation of the lining inside your heart's chambers and valves (the endocardium).

Endocarditis is usually caused by germs that get into your bloodstream and travel to your heart. Once they get inside your heart, the germs can attach to the lining or get trapped in the valves. They start to grow, causing an infection. If not treated quickly, the infection can cause damage to the heart and lead to serious health problems.

What causes endocarditis?

Bacterial infections cause most endocarditis. Normally, many bacteria live in your mouth, on your skin, or in other parts of the body. Sometimes the bacteria can get into your bloodstream from injuries such cuts or scrapes. Dental work and certain surgeries can also allow small amounts of bacteria to enter your bloodstream.

In some cases, fungal infections cause endocarditis. The fungi, such as yeast, can live in parts of your body. Fungal infections generally happen in people who have weakened immune systems that can't stop the fungus from growing. This includes people who have HIV.

Who is more likely to develop endocarditis?

In general, endocarditis is rare. If you're healthy, your immune system usually destroys the germs in your bloodstream before they can cause harm.

But your chance of developing endocarditis may be higher than most people if you:

  • Have certain heart conditions. Damaged or abnormal heart tissue and devices in your heart can trap germs more easily than healthy heart tissue. That means your risk of endocarditis is higher if you have:
    • Heart valve disease.
    • Certain congenital heart defects.
    • A pacemaker or an implantable defibrillator.
    • A heart valve replacement.
  • Are older. Age-related changes to the heart valves, such as mitral valve prolapse or calcium deposits in the aortic valve, create places for germs to attach to the heart.
  • Inject illegal drugs. Unclean needles may carry bacteria into the bloodstream.
  • Have a condition that weakens your immune system.
  • Don't take care of your teeth and gums. Poor dental health makes it easier for germs to get into your bloodstream through your gums and mouth.
  • Have a long-term central venous line, a tube that stays in a large vein for weeks or months for medical treatment.
  • Have already had endocarditis. Endocarditis can damage heart tissue, which increases your risk of getting it again.

What are the symptoms of endocarditis?

Endocarditis symptoms may be severe or very mild. They may start suddenly or slowly. And they can vary from person to person. The possible symptoms of endocarditis include:

  • Fever and chills
  • New or worsening heart murmur (an unusual sound heard between heartbeats)
  • Chest pain
  • Cough
  • Muscle, joint, and back pain
  • Night sweats (heavy sweating during sleep)
  • Shortness of breath (feeling like you can't get enough air)
  • Skin changes, including:
    • Broken blood vessels
    • Painful red or purple bumps
    • Painless flat red spots on the palms of your hands or soles of your feet

What other problems can endocarditis cause?

When the germs are in your heart, they can clump together with blood cells. These clumps can break off and travel through your bloodstream. They may block blood flow, spread infection, or damage your organs, including your brain, lungs, kidneys, and spleen.

Endocarditis may sometimes lead to sepsis, a medical emergency that happens when your body has an extreme response to the infection.

Endocarditis can also cause serious heart problems including:

  • Heart valve damage
  • Heart failure
  • Arrhythmia (a problem with the rate or rhythm of your heartbeat)

How is endocarditis diagnosed?

To find out if you have endocarditis, your doctor will:

  • Ask about your medical history, including your symptoms, recent illnesses, and other health conditions that affect your chance of developing endocarditis.
  • Do a physical exam.
  • Likely order tests, such as:
    • Blood tests to check for signs of infection, bacteria, or fungi in your blood.
    • Chest x-rays.
    • Heart tests.

What are the treatments for endocarditis?

If you have endocarditis, it's important to get treatment quickly. Treatments may include:

  • Medicines
    • Antibiotics to treat bacterial infections. Antibiotics are usually started through an intravenous (IV) line in the hospital.
    • Antifungal medicine to treat fungal infections. Your doctor may suggest taking antifungal medicine for the rest of your life to prevent the infection from coming back.
  • Heart surgery may be needed to repair or replace damaged valves and heart tissue. Surgery may also be done to remove infected tissue.
  • Dental care, especially cleanings, can help reduce the amount of bacteria that grows in your mouth.

Treatment may last weeks, and you may need tests to make sure it's working. Your doctor will also check you for problems that could develop from endocarditis, such as heart failure or an irregular heartbeat.

Can endocarditis be prevented?

If you have a higher chance of developing endocarditis than most people, you can reduce your risk if you:

  • Take good care of your teeth and gums every day
  • Have dental exams and cleaning at your dentist's office every 6 months
  • Make heart-healthy habits part of your daily life to help prevent heart disease
  • Call your health care provider right away if you have symptoms that could be endocarditis

People with the highest risk for bacterial endocarditis need antibiotics before dental visits or certain medical or surgical procedures. Ask your provider if you're part of the highest risk group. If so, let all your providers know about your risk.

NIH: National Heart, Lung, and Blood Institute

[Learn More in MedlinePlus]


Syphilis is a sexually transmitted disease caused by bacteria. It infects the genital area, lips, mouth, or anus of both men and women. You usually get syphilis from sexual contact with someone who has it. It can also pass from mother to baby during pregnancy.

The early stage of syphilis usually causes a single, small, painless sore. Sometimes it causes swelling in nearby lymph nodes. If you do not treat it, syphilis usually causes a non-itchy skin rash, often on your hands and feet. Many people do not notice symptoms for years. Symptoms can go away and come back.

The sores caused by syphilis make it easier to get or give someone HIV during sex. If you are pregnant, syphilis can cause complications, or you could lose your baby. In rare cases, syphilis causes serious health problems and even death.

Syphilis is easy to cure with antibiotics if you catch it early. Correct usage of latex condoms greatly reduces, but does not completely eliminate, the risk of catching or spreading syphilis. If your or your partner is allergic to latex, you can use polyurethane condoms. The most reliable way to avoid infection is to not have anal, vaginal, or oral sex.

Centers for Disease Control and Prevention

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.