2027 ICD-10-CM Diagnosis Code A52Late syphilis

ICD-10-CM Codes›A00–B99›A50-A64›A52

ICD-10-CM A52
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

A52 is a non-billable ICD-10-CM category code for late syphilis, so it cannot be submitted on claims. Use a more specific code from this category instead, such as A52.00, A52.01, A52.02, and A52.03.

Code Identity

ICD-10-CM Code
A52
Billable Status
No — Non-Billable Category
Code Describes
Late syphilis
Short Description
Late syphilis
Same as the full description in the CMS dataset.
Chapter
A50-A64
Infections with a predominantly sexual mode of transmission

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA50-A64Infections with a predominantly sexual mode of transmission
CategoryA52Late syphilis
This CodeA52Late syphilis

Specific Coding for Late syphilisOverview

Non-specific codes like A52 require more characters. Use one of these billable codes instead:

  • A52.0 for Cardiovascular and cerebrovascular syphilis

  • Use A52.00 for Cardiovascular syphilis, unspecified

  • Use A52.01 for Syphilitic aneurysm of aorta

  • Use A52.02 for Syphilitic aortitis

  • Use A52.03 for Syphilitic endocarditis

  • Use A52.04 for Syphilitic cerebral arteritis

  • Use A52.05 for Other cerebrovascular syphilis

  • Use A52.06 for Other syphilitic heart involvement

  • Use A52.09 for Other cardiovascular syphilis

  • A52.1 for Symptomatic neurosyphilis

  • Use A52.10 for Symptomatic neurosyphilis, unspecified

  • Use A52.11 for Tabes dorsalis

  • Use A52.12 for Other cerebrospinal syphilis

  • Use A52.13 for Late syphilitic meningitis

  • Use A52.14 for Late syphilitic encephalitis

  • Use A52.15 for Late syphilitic neuropathy

  • Use A52.16 for Charcot's arthropathy (tabetic)

  • Use A52.17 for General paresis

  • Use A52.19 for Other symptomatic neurosyphilis

  • Use A52.2 for Asymptomatic neurosyphilis

  • Use A52.3 for Neurosyphilis, unspecified

  • A52.7 for Other symptomatic late syphilis

  • Use A52.71 for Late syphilitic oculopathy

  • Use A52.72 for Syphilis of lung and bronchus

  • Use A52.73 for Symptomatic late syphilis of other respiratory organs

  • Use A52.74 for Syphilis of liver and other viscera

  • Use A52.75 for Syphilis of kidney and ureter

  • Use A52.76 for Other genitourinary symptomatic late syphilis

  • Use A52.77 for Syphilis of bone and joint

  • Use A52.78 for Syphilis of other musculoskeletal tissue

  • Use A52.79 for Other symptomatic late syphilis

  • Use A52.8 for Late syphilis, latent

  • Use A52.9 for Late syphilis, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to A52: its own notes plus those printed at block A50-A64 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block A50-A64 Infections with a predominantly sexual mode of transmission applies to 142 codes
  • nonspecific and nongonococcal urethritis (N34.1)
  • Reiter's disease (M02.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block A50-A64 Infections with a predominantly sexual mode of transmission applies to 142 codes
  • human immunodeficiency virus [HIV] disease (B20)
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name A52, its category, or a range that includes it.

Applicable To 1

These notes mention A52.

  • O98.1 Syphilis complicating pregnancy, childbirth and the puerperium
    Conditions in A50-A53 names A50-A53, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming A52: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block A65-A69 Other spirochetal diseases
    syphilis (A50-A53) names A50-A53, which includes this code

Clinical InformationClinical

  • Tertiary Syphilis

    a stage of syphilis that occurs fifteen to thirty years after the initial infection; it can include gumma formation and cardiovascular or central nervous system involvement (neurosyphilis).

Patient EducationClinical

Syphilis

Syphilis is a sexually transmitted infection (STI) caused by bacteria. It infects the genital area, lips, mouth, or anus of both men and women. You usually get syphilis from sexual contact with someone who has it. It can also pass from mother to baby during pregnancy.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About A52Overview

What is the ICD-10 code for late syphilis?

A52 is the ICD-10-CM category for late syphilis, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is A52 (Late syphilis) a billable code?

No. This is a category header that groups the codes for late syphilis, and headers cannot be submitted on claims. Claims for late syphilis need a more specific code from this category, such as A52.00, A52.01, and A52.02.

Can A52 be reported with N34.1?

Not as a rule. The Excludes1 note at block A50-A64, which applies to A52, lists "nonspecific and nongonococcal urethritis (N34.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).