Diagnosis Code E28.3
Information for Medical Professionals
References found for the code E28.3 in the Index of Diseases and Injuries:
- Type 1 Excludes Notes: Type 1 Excludes Notes
A type 1 Excludes note is a pure excludes note. It means “NOT CODED HERE!” An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- pure gonadal dysgenesis (Q99.1)
- Turner's syndrome (Q96.-)
Information for Patients
Also called: Ovarian insufficiency, POF, Primary ovarian insufficiency
Premature ovarian failure (POF) is when a woman's ovaries stop working before she is 40.
POF is different from premature menopause. With premature menopause, your periods stop before age 40. You can no longer get pregnant. The cause can be natural or it can be a disease, surgery, chemotherapy, or radiation. With POF, some women still have occasional periods. They may even get pregnant. In most cases of POF, the cause is unknown.
Missed periods are usually the first sign of POF. Later symptoms may be similar to those of natural menopause:
- Hot flashes
- Night sweats
- Poor concentration
- Decreased sex drive
- Pain during sex
- Vaginal dryness
Doctors diagnose POF by doing a physical exam and lab and imaging tests.
Most women with POF cannot get pregnant naturally. Fertility treatments help a few women; others use donor eggs to have children. There is no treatment that will restore normal ovarian function. However, many health care providers suggest taking hormones until age 50.
NIH: National Institute of Child Health and Human Development
- Follicle-stimulating hormone (FSH) blood test
- Luteinizing hormone (LH) blood test
- Ovarian hypofunction