2027 ICD-10-CM Diagnosis Code C46Kaposi's sarcoma

ICD-10-CM Codes›C00–D49›C45-C49›C46

ICD-10-CM C46
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

C46 is a non-billable ICD-10-CM category code for Kaposi's sarcoma, so it cannot be submitted on claims. Use a more specific code from this category instead, such as C46.0, C46.1, C46.2, and C46.3.

Code Identity

ICD-10-CM Code
C46
Billable Status
No — Non-Billable Category
Code Describes
Kaposi's sarcoma
Short Description
Kaposi's sarcoma
Same as the full description in the CMS dataset.
Chapter
C45-C49
Malignant neoplasms of mesothelial and soft tissue

Code Classification

ChapterC00–D49Neoplasms
SectionC45-C49Malignant neoplasms of mesothelial and soft tissue
CategoryC46Kaposi's sarcoma
This CodeC46Kaposi's sarcoma

Specific Coding for Kaposi's sarcomaOverview

Non-specific codes like C46 require more characters. Use one of these billable codes instead:

  • Use C46.0 for Kaposi's sarcoma of skin

  • Use C46.1 for Kaposi's sarcoma of soft tissue

  • Use C46.2 for Kaposi's sarcoma of palate

  • Use C46.3 for Kaposi's sarcoma of lymph nodes

  • Use C46.4 for Kaposi's sarcoma of gastrointestinal sites

  • C46.5 for Kaposi's sarcoma of lung

  • Use C46.50 for Kaposi's sarcoma of unspecified lung

  • Use C46.51 for Kaposi's sarcoma of right lung

  • Use C46.52 for Kaposi's sarcoma of left lung

  • Use C46.7 for Kaposi's sarcoma of other sites

  • Use C46.9 for Kaposi's sarcoma, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to C46: its own notes plus those printed at Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Code First

The underlying condition named in the note is sequenced before this code.

  • any human immunodeficiency virus [HIV] disease (B20)

Notes

General instructions on how these codes are used.

From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name C46, its category, or a range that includes it.

Applicable To 1

These notes mention C46.

  • Z85.83 Personal history of malignant neoplasm of bone and soft tissue
    Conditions classifiable to C40-C41; C45-C49 names C45-C49, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming C46: its condition is not part of those codes, and both may be reported when the patient has both.

Clinical InformationClinical

  • Sarcoma, Kaposi

    a multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. the tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. kaposi's sarcoma occurs spontaneously in jewish and italian males in europe and the united states. an aggressive variant in young children is endemic in some areas of africa. a third form occurs in about 0.04% of kidney transplant patients. there is also a high incidence in aids patients. (from dorland, 27th ed & holland et al., cancer medicine, 3d ed, pp2105-7) hhv-8 is the suspected cause.

Patient EducationClinical

Kaposi Sarcoma

Kaposi sarcoma, sometimes called KS, is a type of cancer. It causes lesions (abnormal tissue) to grow in different parts of the body, including:

The full article covers:

  • What is Kaposi sarcoma?
  • What causes Kaposi sarcoma and who is more likely to develop it?
  • What are the symptoms of Kaposi sarcoma?
  • How is Kaposi sarcoma diagnosed?
  • What are the treatments for Kaposi sarcoma?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About C46Overview

What is the ICD-10 code for Kaposi's sarcoma?

C46 is the ICD-10-CM category for Kaposi's sarcoma, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is C46 (Kaposi's sarcoma) a billable code?

No. This is a category header that groups the codes for Kaposi's sarcoma, and headers cannot be submitted on claims. Claims for Kaposi's sarcoma need a more specific code from this category, such as C46.0, C46.1, and C46.2.

What is coded first with C46?

The Code First note reads: any human immunodeficiency virus [HIV] disease (B20). When one of these applies, it is sequenced before C46.