2026 ICD-10-CM Diagnosis Code Z85.6Personal history of leukemia
Z85.6 is a billable ICD-10-CM diagnosis code for personal history of leukemia. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 826 through 830, 843 through 845. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. Coders also document this condition as history of acute leukemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Personal history of malignant neoplasm.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for Z85.6.
Present on Admission (POA)Billing
Z85.6 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- History of acute leukemia
- History of acute lymphoid leukemia
- History of acute monocytic leukemia
- History of acute myeloid leukemia
- History of chronic lymphocytic leukemia
- History of leukemia
- History of lymphoid leukemia
- History of monocytic leukemia
- History of myeloid leukemia
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
Type 1 Excludes
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- History
- personal (of) - See Also: History, family (of);
- leukemia - Z85.6
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- History
- personal (of)
- leukemia
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Personal History of Leukemia
an individual history of leukemia.
Patient EducationClinical
Leukemia
Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:
The full article covers:
- What is leukemia?
- What are the types of leukemia?
- What causes leukemia?
- Who is at risk for leukemia?
- What are the symptoms of leukemia?
- How is leukemia diagnosed?
- What are the treatments for leukemia?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Z85.6 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Z85.6Overview
Is Z85.6 (Personal history of malignant neoplasm) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report personal history of leukemia on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does Z85.6 group to?
On inpatient claims, personal history of leukemia maps to MS-DRG 826, 827, 828, 829, 830, 843, 844, 845, with relative weights from 0.8516 to 4.6778 depending on complications. Higher weights mean higher Medicare reimbursement.
Can Z85.6 be a principal diagnosis?
No. The Medicare Code Editor rejects this code as a principal diagnosis because personal history of leukemia describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.
Is Z85.6 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for personal history of leukemia on inpatient claims.
What is the ICD-9 equivalent of Z85.6?
Under the General Equivalence Mappings, personal history of leukemia converts to ICD-9-CM V10.60 (hx of leukemia NOS). The mapping is approximate, so confirm the match fits the documentation.
