Family history of primary malignant neoplasm (Z80) ICD-10-CM
The Z80 code range covers family history of primary malignant neoplasm with 19 ICD-10-CM diagnosis codes. 16 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Codes in the Z80 Range 19 codes · 16 billable
- Z80 Family history of primary malignant neoplasmNon-billable
- Z80.0 Family history of malignant neoplasm of digestive organs
- Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
- Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
- Z80.3 Family history of malignant neoplasm of breast
- Z80.4 Family history of malignant neoplasm of genital organsNon-billable
- Z80.41 Family history of malignant neoplasm of ovary
- Z80.42 Family history of malignant neoplasm of prostate
- Z80.43 Family history of malignant neoplasm of testis
- Z80.44 Family history of malignant neoplasm of fallopian tube(s) New
- Z80.49 Family history of malignant neoplasm of other genital organs
- Z80.5 Family history of malignant neoplasm of urinary tractNon-billable
- Z80.51 Family history of malignant neoplasm of kidney
- Z80.52 Family history of malignant neoplasm of bladder
- Z80.59 Family history of malignant neoplasm of other urinary tract organ
- Z80.6 Family history of leukemia
- Z80.7 Family history of other malignant neoplasms of lymphoid, hematopoietic and related tissues
- Z80.8 Family history of malignant neoplasm of other organs or systems
- Z80.9 Family history of malignant neoplasm, unspecified
About the Z80 Code Range
The ICD-10 code Z80 series is used to document a family history of primary malignant neoplasms, indicating that a patient's relatives have had various types of cancer. These codes help healthcare providers assess hereditary cancer risk based on family medical history.
The main code Z80 covers any family history of malignant neoplasms, while more specific codes classify histories related to particular organ systems. For example, Z80.0 pertains to digestive organ cancers such as colorectal and gastric cancer, often linked to terms like "family history of colorectal cancer" or "hereditary nonpolyposis colon cancer." Codes like Z80.3 specify family history of breast cancer, including early-onset cases in close relatives. Similarly, Z80.41 to Z80.49 cover various genital organ cancers such as ovarian or prostate cancer, reflecting synonyms like "family history of neoplasm of ovary" or "family history of malignant neoplasm of prostate." The section also includes codes for family history of urinary tract malignancies (Z80.5), leukemia (Z80.6), lymphoid and hematopoietic cancers (Z80.7), other organ systems (Z80.8), and unspecified malignant neoplasms (Z80.9). These codes guide clinical risk evaluation and preventive care for individuals with a hereditary predisposition to cancer.
Questions About This Page
How many billable codes are in the Z80 range?
Of the 19 codes in this range, 16 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the Z80 range classify?
The range classifies family history of primary malignant neoplasm. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
