History

"History" References in the ICD-10-CM Index to Diseases and Injuries

References in the ICD-10-CM Index to Diseases and Injuries applicable to the clinical term "history"

  • History
    • family (of) - See Also: History, personal (of);
      • alcohol abuse - Z81.1 Family history of alcohol abuse and dependence
      • allergy NEC - Z84.89 Family history of other specified conditions
      • anemia - Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
      • arthritis - Z82.61 Family history of arthritis
      • asthma - Z82.5 Family history of asthma and other chronic lower respiratory diseases
      • blindness - Z82.1 Family history of blindness and visual loss
      • cardiac death (sudden) - Z82.41 Family history of sudden cardiac death
      • carrier of genetic disease - Z84.81 Family history of carrier of genetic disease
      • chromosomal anomaly - Z82.79 Family history of other congenital malformations, deformations and chromosomal abnormalities
      • chronic
        • disabling disease NEC - Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
        • lower respiratory disease - Z82.5 Family history of asthma and other chronic lower respiratory diseases
      • colonic polyps - Z83.71 Family history of colonic polyps
      • congenital malformations and deformations - Z82.79 Family history of other congenital malformations, deformations and chromosomal abnormalities
        • polycystic kidney - Z82.71 Family history of polycystic kidney
      • consanguinity - Z84.3 Family history of consanguinity
      • deafness - Z82.2 Family history of deafness and hearing loss
      • diabetes mellitus - Z83.3 Family history of diabetes mellitus
      • disability NEC - Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
      • disease or disorder (of)
        • allergic NEC - Z84.89 Family history of other specified conditions
        • behavioral NEC - Z81.8 Family history of other mental and behavioral disorders
        • blood and blood-forming organs - Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
        • cardiovascular NEC - Z82.49 Family history of ischemic heart disease and other diseases of the circulatory system
        • chronic disabling NEC - Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
        • digestive - Z83.79 Family history of other diseases of the digestive system
        • ear NEC - Z83.52 Family history of ear disorders
        • elevated lipoprotein (a) (Lp (a)) - Z83.430 Family history of elevated lipoprotein(a)
        • endocrine NEC - Z83.49 Family history of other endocrine, nutritional and metabolic diseases
        • eye NEC - Z83.518 Family history of other specified eye disorder
          • glaucoma - Z83.511 Family history of glaucoma
        • familial hypercholesterolemia - Z83.42 Family history of familial hypercholesterolemia
        • genitourinary NEC - Z84.2 Family history of other diseases of the genitourinary system
        • glaucoma - Z83.511 Family history of glaucoma
        • hematological - Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
        • immune mechanism - Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
        • infectious NEC - Z83.1 Family history of other infectious and parasitic diseases
        • ischemic heart - Z82.49 Family history of ischemic heart disease and other diseases of the circulatory system
        • kidney - Z84.1 Family history of disorders of kidney and ureter
        • lipoprotein metabolism - Z83.438 Family history of other disorder of lipoprotein metabolism and other lipidemia
        • mental NEC - Z81.8 Family history of other mental and behavioral disorders
        • metabolic - Z83.49 Family history of other endocrine, nutritional and metabolic diseases
        • musculoskeletal NEC - Z82.69 Family history of other diseases of the musculoskeletal system and connective tissue
        • neurological NEC - Z82.0 Family history of epilepsy and other diseases of the nervous system
        • nutritional - Z83.49 Family history of other endocrine, nutritional and metabolic diseases
        • parasitic NEC - Z83.1 Family history of other infectious and parasitic diseases
        • psychiatric NEC - Z81.8 Family history of other mental and behavioral disorders
        • respiratory NEC - Z83.6 Family history of other diseases of the respiratory system
        • skin and subcutaneous tissue NEC - Z84.0 Family history of diseases of the skin and subcutaneous tissue
        • specified NEC - Z84.89 Family history of other specified conditions
      • drug abuse NEC - Z81.3 Family history of other psychoactive substance abuse and dependence
      • elevated lipoprotein (a) (Lp (a)) - Z83.430 Family history of elevated lipoprotein(a)
      • epilepsy - Z82.0 Family history of epilepsy and other diseases of the nervous system
      • familial hypercholesterolemia - Z83.42 Family history of familial hypercholesterolemia
      • genetic disease carrier - Z84.81 Family history of carrier of genetic disease
      • glaucoma - Z83.511 Family history of glaucoma
      • hearing loss - Z82.2 Family history of deafness and hearing loss
      • human immunodeficiency virus (HIV) infection - Z83.0 Family history of human immunodeficiency virus [HIV] disease
      • Huntington's chorea - Z82.0 Family history of epilepsy and other diseases of the nervous system
      • hyperlipidemia, familial combined - Z83.438 Family history of other disorder of lipoprotein metabolism and other lipidemia
      • intellectual disability - Z81.0 Family history of intellectual disabilities
      • leukemia - Z80.6 Family history of leukemia
      • lipidemia NEC - Z83.438 Family history of other disorder of lipoprotein metabolism and other lipidemia
      • malignant neoplasm (of) NOS - Z80.9 Family history of malignant neoplasm, unspecified
        • bladder - Z80.52 Family history of malignant neoplasm of bladder
        • breast - Z80.3 Family history of malignant neoplasm of breast
        • bronchus - Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
        • digestive organ - Z80.0 Family history of malignant neoplasm of digestive organs
        • gastrointestinal tract - Z80.0 Family history of malignant neoplasm of digestive organs
        • genital organ - Z80.49 Family history of malignant neoplasm of other genital organs
          • ovary - Z80.41 Family history of malignant neoplasm of ovary
          • prostate - Z80.42 Family history of malignant neoplasm of prostate
          • specified organ NEC - Z80.49 Family history of malignant neoplasm of other genital organs
          • testis - Z80.43 Family history of malignant neoplasm of testis
        • hematopoietic NEC - Z80.7 Family history of other malignant neoplasms of lymphoid, hematopoietic and related tissues
        • intrathoracic organ NEC - Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
        • kidney - Z80.51 Family history of malignant neoplasm of kidney
        • lung - Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
        • lymphatic NEC - Z80.7 Family history of other malignant neoplasms of lymphoid, hematopoietic and related tissues
        • ovary - Z80.41 Family history of malignant neoplasm of ovary
        • prostate - Z80.42 Family history of malignant neoplasm of prostate
        • respiratory organ NEC - Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
        • specified site NEC - Z80.8 Family history of malignant neoplasm of other organs or systems
        • testis - Z80.43 Family history of malignant neoplasm of testis
        • trachea - Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
        • urinary organ or tract - Z80.59 Family history of malignant neoplasm of other urinary tract organ
          • bladder - Z80.52 Family history of malignant neoplasm of bladder
          • kidney - Z80.51 Family history of malignant neoplasm of kidney
      • mental
        • disorder NEC - Z81.8 Family history of other mental and behavioral disorders
      • multiple endocrine neoplasia (MEN) syndrome - Z83.41 Family history of multiple endocrine neoplasia [MEN] syndrome
      • osteoporosis - Z82.62 Family history of osteoporosis
      • polycystic kidney - Z82.71 Family history of polycystic kidney
      • polyps (colon) - Z83.71 Family history of colonic polyps
      • psychiatric disorder - Z81.8 Family history of other mental and behavioral disorders
      • psychoactive substance abuse NEC - Z81.3 Family history of other psychoactive substance abuse and dependence
      • respiratory condition NEC - Z83.6 Family history of other diseases of the respiratory system
        • asthma and other lower respiratory conditions - Z82.5 Family history of asthma and other chronic lower respiratory diseases
      • self-harmful behavior - Z81.8 Family history of other mental and behavioral disorders
      • SIDS (sudden infant death syndrome) - Z84.82 Family history of sudden infant death syndrome
      • skin condition - Z84.0 Family history of diseases of the skin and subcutaneous tissue
      • specified condition NEC - Z84.89 Family history of other specified conditions
      • stroke (cerebrovascular) - Z82.3 Family history of stroke
      • substance abuse NEC - Z81.4 Family history of other substance abuse and dependence
        • alcohol - Z81.1 Family history of alcohol abuse and dependence
        • drug NEC - Z81.3 Family history of other psychoactive substance abuse and dependence
        • psychoactive NEC - Z81.3 Family history of other psychoactive substance abuse and dependence
        • tobacco - Z81.2 Family history of tobacco abuse and dependence
      • sudden
        • cardiac death - Z82.41 Family history of sudden cardiac death
        • infant death syndrome (SIDS) - Z84.82 Family history of sudden infant death syndrome
      • tobacco abuse - Z81.2 Family history of tobacco abuse and dependence
      • violence, violent behavior - Z81.8 Family history of other mental and behavioral disorders
      • visual loss - Z82.1 Family history of blindness and visual loss
    • personal (of) - See Also: History, family (of);
      • abuse
        • adult - Z91.419 Personal history of unspecified adult abuse
          • forced labor or sexual exploitation - Z91.42 Personal history of forced labor or sexual exploitation
          • physical and sexual - Z91.410 Personal history of adult physical and sexual abuse
          • psychological - Z91.411 Personal history of adult psychological abuse
        • childhood - Z62.819 Personal history of unspecified abuse in childhood
          • forced labor or sexual exploitation in childhood - Z62.813 Personal history of forced labor or sexual exploitation in childhood
          • physical - Z62.810 Personal history of physical and sexual abuse in childhood
          • psychological - Z62.811 Personal history of psychological abuse in childhood
          • sexual - Z62.810 Personal history of physical and sexual abuse in childhood
      • alcohol dependence - F10.21 Alcohol dependence, in remission
      • allergy (to) - Z88.9 Allergy status to unspecified drugs, medicaments and biological substances status
        • analgesic agent NEC - Z88.6 Allergy status to analgesic agent status
        • anesthetic - Z88.4 Allergy status to anesthetic agent status
        • antibiotic agent NEC - Z88.1 Allergy status to other antibiotic agents status
        • anti-infective agent NEC - Z88.3 Allergy status to other anti-infective agents status
        • contrast media - Z91.041 Radiographic dye allergy status
        • drugs, medicaments and biological substances - Z88.9 Allergy status to unspecified drugs, medicaments and biological substances status
          • specified NEC - Z88.8 Allergy status to other drugs, medicaments and biological substances status
        • food - Z91.018 Allergy to other foods
          • additives - Z91.02 Food additives allergy status
          • eggs - Z91.012 Allergy to eggs
          • milk products - Z91.011 Allergy to milk products
          • peanuts - Z91.010 Allergy to peanuts
          • seafood - Z91.013 Allergy to seafood
          • specified food NEC - Z91.018 Allergy to other foods
        • insect - Z91.038 Other insect allergy status
        • latex - Z91.040 Latex allergy status
        • medicinal agents - Z88.9 Allergy status to unspecified drugs, medicaments and biological substances status
          • specified NEC - Z88.8 Allergy status to other drugs, medicaments and biological substances status
        • narcotic agent NEC - Z88.5 Allergy status to narcotic agent status
        • nonmedicinal agents - Z91.048 Other nonmedicinal substance allergy status
        • penicillin - Z88.0 Allergy status to penicillin
        • serum - Z88.7 Allergy status to serum and vaccine status
        • specified NEC - Z91.09 Other allergy status, other than to drugs and biological substances
        • sulfonamides - Z88.2 Allergy status to sulfonamides status
        • vaccine - Z88.7 Allergy status to serum and vaccine status
      • anaphylactic shock - Z87.892 Personal history of anaphylaxis
      • anaphylaxis - Z87.892 Personal history of anaphylaxis
      • behavioral disorders - Z86.59 Personal history of other mental and behavioral disorders
      • benign carcinoid tumor - Z86.012 Personal history of benign carcinoid tumor
      • benign neoplasm - Z86.018 Personal history of other benign neoplasm
        • brain - Z86.011 Personal history of benign neoplasm of the brain
        • carcinoid - Z86.012 Personal history of benign carcinoid tumor
        • colonic polyps - Z86.010 Personal history of colonic polyps
      • brain injury (traumatic) - Z87.820 Personal history of traumatic brain injury
      • breast implant removal - Z98.86 Personal history of breast implant removal
      • calculi, renal - Z87.442 Personal history of urinary calculi
      • cancer - See: History, personal (of), malignant neoplasm (of);
      • cardiac arrest (death), suscessfully resuscitated - Z86.74 Personal history of sudden cardiac arrest
      • cerebral infarction without residual deficit - Z86.73 Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits
      • cervical dysplasia - Z87.410 Personal history of cervical dysplasia
      • chemotherapy for neoplastic condition - Z92.21 Personal history of antineoplastic chemotherapy
      • childhood abuse - See: History, personal (of), abuse;
      • cleft lip (corrected) - Z87.730 Personal history of (corrected) cleft lip and palate
      • cleft palate (corrected) - Z87.730 Personal history of (corrected) cleft lip and palate
      • collapsed vertebra (healed) - Z87.311 Personal history of (healed) other pathological fracture
        • due to osteoporosis - Z87.310 Personal history of (healed) osteoporosis fracture
      • combat and operational stress reaction - Z86.51 Personal history of combat and operational stress reaction
      • congenital malformation (corrected) - Z87.798 Personal history of other (corrected) congenital malformations
        • circulatory system (corrected) - Z87.74 Personal history of (corrected) congenital malformations of heart and circulatory system
        • digestive system (corrected) NEC - Z87.738 Personal history of other specified (corrected) congenital malformations of digestive system
        • ear (corrected) - Z87.721 Personal history of (corrected) congenital malformations of ear
        • eye (corrected) - Z87.720 Personal history of (corrected) congenital malformations of eye
        • face and neck (corrected) - Z87.790 Personal history of (corrected) congenital malformations of face and neck
        • genitourinary system (corrected) NEC - Z87.718 Personal history of other specified (corrected) congenital malformations of genitourinary system
        • heart (corrected) - Z87.74 Personal history of (corrected) congenital malformations of heart and circulatory system
        • integument (corrected) - Z87.76 Personal history of (corrected) congenital malformations of integument, limbs and musculoskeletal system
        • limb (s) (corrected) - Z87.76 Personal history of (corrected) congenital malformations of integument, limbs and musculoskeletal system
        • musculoskeletal system (corrected) - Z87.76 Personal history of (corrected) congenital malformations of integument, limbs and musculoskeletal system
        • neck (corrected) - Z87.790 Personal history of (corrected) congenital malformations of face and neck
        • nervous system (corrected) NEC - Z87.728 Personal history of other specified (corrected) congenital malformations of nervous system and sense organs
        • respiratory system (corrected) - Z87.75 Personal history of (corrected) congenital malformations of respiratory system
        • sense organs (corrected) NEC - Z87.728 Personal history of other specified (corrected) congenital malformations of nervous system and sense organs
        • specified NEC - Z87.798 Personal history of other (corrected) congenital malformations
      • contraception - Z92.0 Personal history of contraception
      • deployment (military) - Z91.82 Personal history of military deployment
      • diabetic foot ulcer - Z86.31 Personal history of diabetic foot ulcer
      • disease or disorder (of) - Z87.898 Personal history of other specified conditions
        • blood and blood-forming organs - Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
        • circulatory system - Z86.79 Personal history of other diseases of the circulatory system
          • specified condition NEC - Z86.79 Personal history of other diseases of the circulatory system
        • connective tissue NEC - Z87.39 Personal history of other diseases of the musculoskeletal system and connective tissue
        • digestive system - Z87.19 Personal history of other diseases of the digestive system
          • colonic polyp - Z86.010 Personal history of colonic polyps
          • peptic ulcer disease - Z87.11 Personal history of peptic ulcer disease
          • specified condition NEC - Z87.19 Personal history of other diseases of the digestive system
        • ear - Z86.69 Personal history of other diseases of the nervous system and sense organs
        • endocrine - Z86.39 Personal history of other endocrine, nutritional and metabolic disease
          • diabetic foot ulcer - Z86.31 Personal history of diabetic foot ulcer
          • gestational diabetes - Z86.32 Personal history of gestational diabetes
          • specified type NEC - Z86.39 Personal history of other endocrine, nutritional and metabolic disease
        • eye - Z86.69 Personal history of other diseases of the nervous system and sense organs
        • genital (track) system NEC
          • female - Z87.42 Personal history of other diseases of the female genital tract
          • male - Z87.438 Personal history of other diseases of male genital organs
        • hematological - Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
        • Hodgkin - Z85.71 Personal history of Hodgkin lymphoma
        • immune mechanism - Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
        • infectious - Z86.19 Personal history of other infectious and parasitic diseases
          • malaria - Z86.13 Personal history of malaria
          • Methicillin resistant Staphylococcus aureus (MRSA) - Z86.14 Personal history of Methicillin resistant Staphylococcus aureus infection
          • poliomyelitis - Z86.12 Personal history of poliomyelitis
          • specified NEC - Z86.19 Personal history of other infectious and parasitic diseases
          • tuberculosis - Z86.11 Personal history of tuberculosis
        • mental NEC - Z86.59 Personal history of other mental and behavioral disorders
        • metabolic - Z86.39 Personal history of other endocrine, nutritional and metabolic disease
          • diabetic foot ulcer - Z86.31 Personal history of diabetic foot ulcer
          • gestational diabetes - Z86.32 Personal history of gestational diabetes
          • specified type NEC - Z86.39 Personal history of other endocrine, nutritional and metabolic disease
        • musculoskeletal NEC - Z87.39 Personal history of other diseases of the musculoskeletal system and connective tissue
        • nervous system - Z86.69 Personal history of other diseases of the nervous system and sense organs
        • nutritional - Z86.39 Personal history of other endocrine, nutritional and metabolic disease
        • parasitic - Z86.19 Personal history of other infectious and parasitic diseases
        • respiratory system NEC - Z87.09 Personal history of other diseases of the respiratory system
        • sense organs - Z86.69 Personal history of other diseases of the nervous system and sense organs
        • skin - Z87.2 Personal history of diseases of the skin and subcutaneous tissue
        • specified site or type NEC - Z87.898 Personal history of other specified conditions
        • subcutaneous tissue - Z87.2 Personal history of diseases of the skin and subcutaneous tissue
        • trophoblastic - Z87.59 Personal history of other complications of pregnancy, childbirth and the puerperium
        • urinary system NEC - Z87.448 Personal history of other diseases of urinary system
      • drug dependence - See: Dependence, drug, by type, in remission;
      • drug therapy
        • antineoplastic chemotherapy - Z92.21 Personal history of antineoplastic chemotherapy
        • estrogen - Z92.23 Personal history of estrogen therapy
        • immunosupression - Z92.25 Personal history of immunosupression therapy
        • inhaled steroids - Z92.240 Personal history of inhaled steroid therapy
        • monoclonal drug - Z92.22 Personal history of monoclonal drug therapy
        • specified NEC - Z92.29 Personal history of other drug therapy
        • steroid - Z92.241 Personal history of systemic steroid therapy
        • systemic steroids - Z92.241 Personal history of systemic steroid therapy
      • dysplasia
        • cervical (mild) (moderate) - Z87.410 Personal history of cervical dysplasia
          • severe (grade III) - Z86.001 Personal history of in-situ neoplasm of cervix uteri
        • prostatic - Z87.430 Personal history of prostatic dysplasia
        • vaginal (mild) (moderate) - Z87.411 Personal history of vaginal dysplasia
          • severe (grade III) - Z86.002 Personal history of in-situ neoplasm of other and unspecified genital organs
        • vulvar (mild) (moderate) - Z87.412 Personal history of vulvar dysplasia
          • severe (grade III) - Z86.002 Personal history of in-situ neoplasm of other and unspecified genital organs
      • embolism (venous) - Z86.718 Personal history of other venous thrombosis and embolism
        • pulmonary - Z86.711 Personal history of pulmonary embolism
      • encephalitis - Z86.61 Personal history of infections of the central nervous system
      • estrogen therapy - Z92.23 Personal history of estrogen therapy
      • extracorporeal membrane oxygenation (ECMO) - Z92.81 Personal history of extracorporeal membrane oxygenation (ECMO)
      • failed conscious sedation - Z92.83 Personal history of failed moderate sedation
      • failed moderate sedation - Z92.83 Personal history of failed moderate sedation
      • fall, falling - Z91.81 History of falling
      • forced labor or sexual exploitation - Z91.42 Personal history of forced labor or sexual exploitation
        • in childhood - Z62.813 Personal history of forced labor or sexual exploitation in childhood
      • fracture (healed)
        • fatigue - Z87.312 Personal history of (healed) stress fracture
        • fragility - Z87.310 Personal history of (healed) osteoporosis fracture
        • osteoporosis - Z87.310 Personal history of (healed) osteoporosis fracture
        • pathological NEC - Z87.311 Personal history of (healed) other pathological fracture
        • stress - Z87.312 Personal history of (healed) stress fracture
        • traumatic - Z87.81 Personal history of (healed) traumatic fracture
      • gestational diabetes - Z86.32 Personal history of gestational diabetes
      • hepatitis
        • B - Z86.19 Personal history of other infectious and parasitic diseases
        • C - Z86.19 Personal history of other infectious and parasitic diseases
      • Hodgkin disease - Z85.71 Personal history of Hodgkin lymphoma
      • hyperthermia, malignant - Z88.4 Allergy status to anesthetic agent status
      • hypospadias (corrected) - Z87.710 Personal history of (corrected) hypospadias
      • hysterectomy - Z90.710 Acquired absence of both cervix and uterus
      • immunosupression therapy - Z92.25 Personal history of immunosupression therapy
      • in situ neoplasm
        • breast - Z86.000 Personal history of in-situ neoplasm of breast
        • cervix uteri - Z86.001 Personal history of in-situ neoplasm of cervix uteri
        • digestive organs, specified NEC - Z86.004 Personal history of in-situ neoplasm of other and unspecified digestive organs
        • esophagus - Z86.003 Personal history of in-situ neoplasm of oral cavity, esophagus and stomach
        • genital organs, specified NEC - Z86.002 Personal history of in-situ neoplasm of other and unspecified genital organs
        • melanoma - Z86.006 Personal history of melanoma in-situ
        • middle ear - Z86.005 Personal history of in-situ neoplasm of middle ear and respiratory system
        • oral cavity - Z86.003 Personal history of in-situ neoplasm of oral cavity, esophagus and stomach
        • respiratory system - Z86.005 Personal history of in-situ neoplasm of middle ear and respiratory system
        • skin - Z86.007 Personal history of in-situ neoplasm of skin
        • specified NEC - Z86.008 Personal history of in-situ neoplasm of other site
        • stomach - Z86.003 Personal history of in-situ neoplasm of oral cavity, esophagus and stomach
      • in utero procedure during pregnancy - Z98.870 Personal history of in utero procedure during pregnancy
      • in utero procedure while a fetus - Z98.871 Personal history of in utero procedure while a fetus
      • infection NEC - Z86.19 Personal history of other infectious and parasitic diseases
        • central nervous system - Z86.61 Personal history of infections of the central nervous system
        • latent tuberculosis - Z86.15 Personal history of latent tuberculosis infection
        • Methicillin resistant Staphylococcus aureus (MRSA) - Z86.14 Personal history of Methicillin resistant Staphylococcus aureus infection
        • urinary (recurrent) (tract) - Z87.440 Personal history of urinary (tract) infections
      • injury NEC - Z87.828 Personal history of other (healed) physical injury and trauma
      • irradiation - Z92.3 Personal history of irradiation
      • kidney stones - Z87.442 Personal history of urinary calculi
      • latent tuberculosis infection - Z86.15 Personal history of latent tuberculosis infection
      • leukemia - Z85.6 Personal history of leukemia
      • lymphoma (non-Hodgkin) - Z85.72 Personal history of non-Hodgkin lymphomas
      • malignant melanoma (skin) - Z85.820 Personal history of malignant melanoma of skin
      • malignant neoplasm (of) - Z85.9 Personal history of malignant neoplasm, unspecified
        • accessory sinuses - Z85.22 Personal history of malignant neoplasm of nasal cavities, middle ear, and accessory sinuses
        • anus NEC - Z85.048 Personal history of other malignant neoplasm of rectum, rectosigmoid junction, and anus
          • carcinoid - Z85.040 Personal history of malignant carcinoid tumor of rectum
        • bladder - Z85.51 Personal history of malignant neoplasm of bladder
        • bone - Z85.830 Personal history of malignant neoplasm of bone
        • brain - Z85.841 Personal history of malignant neoplasm of brain
        • breast - Z85.3 Personal history of malignant neoplasm of breast
        • bronchus NEC - Z85.118 Personal history of other malignant neoplasm of bronchus and lung
          • carcinoid - Z85.110 Personal history of malignant carcinoid tumor of bronchus and lung
        • carcinoid - See: History, personal (of), malignant neoplasm, by site, carcinioid;
        • cervix - Z85.41 Personal history of malignant neoplasm of cervix uteri
        • colon NEC - Z85.038 Personal history of other malignant neoplasm of large intestine
          • carcinoid - Z85.030 Personal history of malignant carcinoid tumor of large intestine
        • digestive organ - Z85.00 Personal history of malignant neoplasm of unspecified digestive organ
          • specified NEC - Z85.09 Personal history of malignant neoplasm of other digestive organs
        • endocrine gland NEC - Z85.858 Personal history of malignant neoplasm of other endocrine glands
        • epididymis - Z85.48 Personal history of malignant neoplasm of epididymis
        • esophagus - Z85.01 Personal history of malignant neoplasm of esophagus
        • eye - Z85.840 Personal history of malignant neoplasm of eye
        • gastrointestinal tract - See: History, malignant neoplasm, digestive organ;
        • genital organ
          • female - Z85.40 Personal history of malignant neoplasm of unspecified female genital organ
            • specified NEC - Z85.44 Personal history of malignant neoplasm of other female genital organs
          • male - Z85.45 Personal history of malignant neoplasm of unspecified male genital organ
            • specified NEC - Z85.49 Personal history of malignant neoplasm of other male genital organs
        • hematopoietic NEC - Z85.79 Personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues
        • intrathoracic organ - Z85.20 Personal history of malignant neoplasm of unspecified respiratory organ
        • kidney NEC - Z85.528 Personal history of other malignant neoplasm of kidney
          • carcinoid - Z85.520 Personal history of malignant carcinoid tumor of kidney
        • large intestine NEC - Z85.038 Personal history of other malignant neoplasm of large intestine
          • carcinoid - Z85.030 Personal history of malignant carcinoid tumor of large intestine
        • larynx - Z85.21 Personal history of malignant neoplasm of larynx
        • liver - Z85.05 Personal history of malignant neoplasm of liver
        • lung NEC - Z85.118 Personal history of other malignant neoplasm of bronchus and lung
          • carcinoid - Z85.110 Personal history of malignant carcinoid tumor of bronchus and lung
        • mediastinum - Z85.29 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
        • Merkel cell - Z85.821 Personal history of Merkel cell carcinoma
        • middle ear - Z85.22 Personal history of malignant neoplasm of nasal cavities, middle ear, and accessory sinuses
        • nasal cavities - Z85.22 Personal history of malignant neoplasm of nasal cavities, middle ear, and accessory sinuses
        • nervous system NEC - Z85.848 Personal history of malignant neoplasm of other parts of nervous tissue
        • oral cavity - Z85.819 Personal history of malignant neoplasm of unspecified site of lip, oral cavity, and pharynx
          • specified site NEC - Z85.818 Personal history of malignant neoplasm of other sites of lip, oral cavity, and pharynx
        • ovary - Z85.43 Personal history of malignant neoplasm of ovary
        • pancreas - Z85.07 Personal history of malignant neoplasm of pancreas
        • pelvis - Z85.53 Personal history of malignant neoplasm of renal pelvis
        • pharynx - Z85.819 Personal history of malignant neoplasm of unspecified site of lip, oral cavity, and pharynx
          • specified site NEC - Z85.818 Personal history of malignant neoplasm of other sites of lip, oral cavity, and pharynx
        • pleura - Z85.29 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
        • prostate - Z85.46 Personal history of malignant neoplasm of prostate
        • rectosigmoid junction NEC - Z85.048 Personal history of other malignant neoplasm of rectum, rectosigmoid junction, and anus
          • carcinoid - Z85.040 Personal history of malignant carcinoid tumor of rectum
        • rectum NEC - Z85.048 Personal history of other malignant neoplasm of rectum, rectosigmoid junction, and anus
          • carcinoid - Z85.040 Personal history of malignant carcinoid tumor of rectum
        • respiratory organ - Z85.20 Personal history of malignant neoplasm of unspecified respiratory organ
        • sinuses, accessory - Z85.22 Personal history of malignant neoplasm of nasal cavities, middle ear, and accessory sinuses
        • skin NEC - Z85.828 Personal history of other malignant neoplasm of skin
          • melanoma - Z85.820 Personal history of malignant melanoma of skin
          • Merkel cell - Z85.821 Personal history of Merkel cell carcinoma
        • small intestine NEC - Z85.068 Personal history of other malignant neoplasm of small intestine
          • carcinoid - Z85.060 Personal history of malignant carcinoid tumor of small intestine
        • soft tissue - Z85.831 Personal history of malignant neoplasm of soft tissue
        • specified site NEC - Z85.89 Personal history of malignant neoplasm of other organs and systems
        • stomach NEC - Z85.028 Personal history of other malignant neoplasm of stomach
          • carcinoid - Z85.020 Personal history of malignant carcinoid tumor of stomach
        • testis - Z85.47 Personal history of malignant neoplasm of testis
        • thymus NEC - Z85.238 Personal history of other malignant neoplasm of thymus
          • carcinoid - Z85.230 Personal history of malignant carcinoid tumor of thymus
        • thyroid - Z85.850 Personal history of malignant neoplasm of thyroid
        • tongue - Z85.810 Personal history of malignant neoplasm of tongue
        • trachea - Z85.12 Personal history of malignant neoplasm of trachea
        • ureter - Z85.54 Personal history of malignant neoplasm of ureter
        • urinary organ or tract - Z85.50 Personal history of malignant neoplasm of unspecified urinary tract organ
          • specified NEC - Z85.59 Personal history of malignant neoplasm of other urinary tract organ
        • uterus - Z85.42 Personal history of malignant neoplasm of other parts of uterus
      • maltreatment - Z91.89 Other specified personal risk factors, not elsewhere classified
      • medical treatment NEC - Z92.89 Personal history of other medical treatment
      • melanoma - Z85.820 Personal history of malignant melanoma of skin
        • in situ - Z86.006 Personal history of melanoma in-situ
        • malignant (skin) - Z85.820 Personal history of malignant melanoma of skin
      • meningitis - Z86.61 Personal history of infections of the central nervous system
      • mental disorder - Z86.59 Personal history of other mental and behavioral disorders
      • Merkel cell carcinoma (skin) - Z85.821 Personal history of Merkel cell carcinoma
      • Methicillin resistant Staphylococcus aureus (MRSA) - Z86.14 Personal history of Methicillin resistant Staphylococcus aureus infection
      • military deployment - Z91.82 Personal history of military deployment
      • military war, peacekeeping and humanitarian deployment (current or past conflict) - Z91.82 Personal history of military deployment
      • myocardial infarction (old) - I25.2 Old myocardial infarction
      • neglect (in)
        • adult - Z91.412 Personal history of adult neglect
        • childhood - Z62.812 Personal history of neglect in childhood
      • neoplasia
        • anal intraepithelial, III [AIN III] - Z86.004 Personal history of in-situ neoplasm of other and unspecified digestive organs
        • high-grade prostatic intraepithelial, III [HGPIN III] - Z86.002 Personal history of in-situ neoplasm of other and unspecified genital organs
        • vaginal intraepithelial, III [VAIN III] - Z86.002 Personal history of in-situ neoplasm of other and unspecified genital organs
        • vulvar intraepithelial, III [VIN III] - Z86.002 Personal history of in-situ neoplasm of other and unspecified genital organs
      • neoplasm
        • benign - Z86.018 Personal history of other benign neoplasm
          • brain - Z86.011 Personal history of benign neoplasm of the brain
          • colon polyp - Z86.010 Personal history of colonic polyps
        • in situ
          • breast - Z86.000 Personal history of in-situ neoplasm of breast
          • cervix uteri - Z86.001 Personal history of in-situ neoplasm of cervix uteri
          • digestive organs, specified NEC - Z86.004 Personal history of in-situ neoplasm of other and unspecified digestive organs
          • esophagus - Z86.003 Personal history of in-situ neoplasm of oral cavity, esophagus and stomach
          • genital organs, specified NEC - Z86.002 Personal history of in-situ neoplasm of other and unspecified genital organs
          • melanoma - Z86.006 Personal history of melanoma in-situ
          • middle ear - Z86.005 Personal history of in-situ neoplasm of middle ear and respiratory system
          • oral cavity - Z86.003 Personal history of in-situ neoplasm of oral cavity, esophagus and stomach
          • respiratory system - Z86.005 Personal history of in-situ neoplasm of middle ear and respiratory system
          • skin - Z86.007 Personal history of in-situ neoplasm of skin
          • specified NEC - Z86.008 Personal history of in-situ neoplasm of other site
          • stomach - Z86.003 Personal history of in-situ neoplasm of oral cavity, esophagus and stomach
        • malignant - See: History of, malignant neoplasm;
        • uncertain behavior - Z86.03 Personal history of neoplasm of uncertain behavior
      • nephrotic syndrome - Z87.441 Personal history of nephrotic syndrome
      • nicotine dependence - Z87.891 Personal history of nicotine dependence
      • noncompliance with medical treatment or regimen - See: Noncompliance;
      • nutritional deficiency - Z86.39 Personal history of other endocrine, nutritional and metabolic disease
      • obstetric complications - Z87.59 Personal history of other complications of pregnancy, childbirth and the puerperium
        • childbirth - Z87.59 Personal history of other complications of pregnancy, childbirth and the puerperium
        • pregnancy - Z87.59 Personal history of other complications of pregnancy, childbirth and the puerperium
        • pre-term labor - Z87.51 Personal history of pre-term labor
        • puerperium - Z87.59 Personal history of other complications of pregnancy, childbirth and the puerperium
      • osteoporosis fractures - Z87.31 Personal history of (healed) nontraumatic fracture
      • parasuicide (attempt) - Z91.5 Personal history of self-harm
      • physical trauma NEC - Z87.828 Personal history of other (healed) physical injury and trauma
        • self-harm or suicide attempt - Z91.5 Personal history of self-harm
      • pneumonia (recurrent) - Z87.01 Personal history of pneumonia (recurrent)
      • poisoning NEC - Z91.89 Other specified personal risk factors, not elsewhere classified
        • self-harm or suicide attempt - Z91.5 Personal history of self-harm
      • poor personal hygiene - Z91.89 Other specified personal risk factors, not elsewhere classified
      • preterm labor - Z87.51 Personal history of pre-term labor
      • procedure during pregnancy - Z98.870 Personal history of in utero procedure during pregnancy
      • procedure while a fetus - Z98.871 Personal history of in utero procedure while a fetus
      • prolonged reversible ischemic neurologic deficit (PRIND) - Z86.73 Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits
      • prostatic dysplasia - Z87.430 Personal history of prostatic dysplasia
      • psychological
        • abuse
          • adult - Z91.411 Personal history of adult psychological abuse
          • child - Z62.811 Personal history of psychological abuse in childhood
        • trauma, specified NEC - Z91.49 Other personal history of psychological trauma, not elsewhere classified
      • radiation therapy - Z92.3 Personal history of irradiation
      • removal
        • implant
          • breast - Z98.86 Personal history of breast implant removal
      • renal calculi - Z87.442 Personal history of urinary calculi
      • respiratory condition NEC - Z87.09 Personal history of other diseases of the respiratory system
      • retained foreign body fully removed - Z87.821 Personal history of retained foreign body fully removed
      • risk factors NEC - Z91.89 Other specified personal risk factors, not elsewhere classified
      • self-harm - Z91.5 Personal history of self-harm
      • self-poisoning attempt - Z91.5 Personal history of self-harm
      • sex reassignment - Z87.890 Personal history of sex reassignment
      • sleep-wake cycle problem - Z72.821 Inadequate sleep hygiene
      • specified NEC - Z87.898 Personal history of other specified conditions
      • steroid therapy (systemic) - Z92.241 Personal history of systemic steroid therapy
        • inhaled - Z92.240 Personal history of inhaled steroid therapy
      • stroke without residual deficits - Z86.73 Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits
      • substance abuse NEC F10-F19
      • sudden cardiac arrest - Z86.74 Personal history of sudden cardiac arrest
      • sudden cardiac death successfully resuscitated - Z86.74 Personal history of sudden cardiac arrest
      • suicide attempt - Z91.5 Personal history of self-harm
      • surgery NEC - Z98.890 Other specified postprocedural states
        • sex reassignment - Z87.890 Personal history of sex reassignment
        • transplant - See: Transplant;
        • with uterine scar - Z98.891 History of uterine scar from previous surgery
      • thrombophlebitis - Z86.72 Personal history of thrombophlebitis
      • thrombosis (venous) - Z86.718 Personal history of other venous thrombosis and embolism
        • pulmonary - Z86.711 Personal history of pulmonary embolism
      • tobacco dependence - Z87.891 Personal history of nicotine dependence
      • transient ischemic attack (TIA) without residual deficits - Z86.73 Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits
      • trauma (physical) NEC - Z87.828 Personal history of other (healed) physical injury and trauma
        • psychological NEC - Z91.49 Other personal history of psychological trauma, not elsewhere classified
        • self-harm - Z91.5 Personal history of self-harm
      • traumatic brain injury - Z87.820 Personal history of traumatic brain injury
      • tuberculosis, latent infection - Z86.15 Personal history of latent tuberculosis infection
      • unhealthy sleep-wake cycle - Z72.821 Inadequate sleep hygiene
      • unintended awareness under general anesthesia - Z92.84 Personal history of unintended awareness under general anesthesia
      • urinary (recurrent) (tract) infection (s) - Z87.440 Personal history of urinary (tract) infections
      • urinary calculi - Z87.442 Personal history of urinary calculi
      • uterine scar from previous surgery - Z98.891 History of uterine scar from previous surgery
      • vaginal dysplasia - Z87.411 Personal history of vaginal dysplasia
      • venous thrombosis or embolism - Z86.718 Personal history of other venous thrombosis and embolism
        • pulmonary - Z86.711 Personal history of pulmonary embolism
      • vulvar dysplasia - Z87.412 Personal history of vulvar dysplasia

Applicable Clinical Terms Definitions

Adult: A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.

Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Arthritis: Acute or chronic inflammation of JOINTS.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Bees: Insect members of the superfamily Apoidea, found almost everywhere, particularly on flowers. About 3500 species occur in North America. They differ from most WASPS in that their young are fed honey and pollen rather than animal food.

Blindness: The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.

Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

Breast: In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.

Death: Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.

Central Nervous System: The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.

Cervix Uteri: The neck portion of the UTERUS between the lower isthmus and the VAGINA forming the cervical canal.

Cervix Uteri: The neck portion of the UTERUS between the lower isthmus and the VAGINA forming the cervical canal.

Child: A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.

Colonic Polyps: Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.

Colonic Polyps: Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.

Consanguinity: The magnitude of INBREEDING in humans.

Contraception: Prevention of CONCEPTION by blocking fertility temporarily, or permanently (STERILIZATION, REPRODUCTIVE). Common means of reversible contraception include NATURAL FAMILY PLANNING METHODS; CONTRACEPTIVE AGENTS; or CONTRACEPTIVE DEVICES.

Contrast Media: Substances used to allow enhanced visualization of tissues.

Deafness: A general term for the complete loss of the ability to hear from both ears.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Digestive System: A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).

Drug Therapy: The use of DRUGS to treat a DISEASE or its symptoms. One example is the use of ANTINEOPLASTIC AGENTS to treat CANCER.

Ear: The hearing and equilibrium system of the body. It consists of three parts: the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR. Sound waves are transmitted through this organ where vibration is transduced to nerve signals that pass through the ACOUSTIC NERVE to the CENTRAL NERVOUS SYSTEM. The inner ear also contains the vestibular organ that maintains equilibrium by transducing signals to the VESTIBULAR NERVE.

Eggs: Animal reproductive bodies, or the contents thereof, used as food. The concept is differentiated from OVUM, the anatomic or physiologic entity.

Encephalitis: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.

Epididymis: The convoluted cordlike structure attached to the posterior of the TESTIS. Epididymis consists of the head (caput), the body (corpus), and the tail (cauda). A network of ducts leaving the testis joins into a common epididymal tubule proper which provides the transport, storage, and maturation of SPERMATOZOA.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Esophagus: The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.

Estrogens: Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.

Eye: The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Female:

Food: Substances taken in by the body to provide nourishment.

Gastrointestinal Tract: Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Hearing Loss: A general term for the complete or partial loss of the ability to hear from one or both ears.

Hepatitis: INFLAMMATION of the LIVER.

History: Record and study of past events.

Hodgkin Disease: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.

Hysterectomy: Excision of the uterus.

Insecta: Members of the phylum ARTHROPODA composed or organisms characterized by division into three parts: head, thorax, and abdomen. They are the dominant group of animals on earth with several hundred thousand different kinds. Three orders, HEMIPTERA; DIPTERA; and SIPHONAPTERA; are of medical interest in that they cause disease in humans and animals. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p1).

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.

Larynx: A tubular organ of VOICE production. It is located in the anterior neck, superior to the TRACHEA and inferior to the tongue and HYOID BONE.

Latex: A milky, product excreted from the latex canals of a variety of plant species that contain cauotchouc. Latex is composed of 25-35% caoutchouc, 60-75% water, 2% protein, 2% resin, 1.5% sugar & 1% ash. RUBBER is made by the removal of water from latex.(From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed). Hevein proteins are responsible for LATEX HYPERSENSITIVITY. Latexes are used as inert vehicles to carry antibodies or antigens in LATEX FIXATION TESTS.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.

Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Male:

Mediastinum: A membrane in the midline of the THORAX of mammals. It separates the lungs between the STERNUM in front and the VERTEBRAL COLUMN behind. It also surrounds the HEART, TRACHEA, ESOPHAGUS, THYMUS, and LYMPH NODES.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Meningitis: Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Ear, Middle: The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat.

Nasal Cavity: The proximal portion of the respiratory passages on either side of the NASAL SEPTUM. Nasal cavities, extending from the nares to the NASOPHARYNX, are lined with ciliated NASAL MUCOSA.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Nervous System: The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)

Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Ovary: The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.

Pancreas: A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.

Pelvis: The space or compartment surrounded by the pelvic girdle (bony pelvis). It is subdivided into the greater pelvis and LESSER PELVIS. The pelvic girdle is formed by the PELVIC BONES and SACRUM.

Penicillins: A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)

Pharynx: A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx).

Pleura: The thin serous membrane enveloping the lungs (LUNG) and lining the THORACIC CAVITY. Pleura consist of two layers, the inner visceral pleura lying next to the pulmonary parenchyma and the outer parietal pleura. Between the two layers is the PLEURAL CAVITY which contains a thin film of liquid.

Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)

Polycystic Kidney Diseases: Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Prostate: A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.

Respiratory System: The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.

Seafood: Marine fish and shellfish used as food or suitable for food. (Webster, 3d ed) SHELLFISH and FISH PRODUCTS are more specific types of SEAFOOD.

Sense Organs: Specialized organs adapted for the reception of stimuli by the NERVOUS SYSTEM.

Serum: The clear portion of BLOOD that is left after BLOOD COAGULATION to remove BLOOD CELLS and clotting proteins.

Skin: The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

Stomach: An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.

Subcutaneous Tissue: Loose connective tissue lying under the DERMIS, which binds SKIN loosely to subjacent tissues. It may contain a pad of ADIPOCYTES, which vary in number according to the area of the body and vary in size according to the nutritional state.

Sulfonamides: A group of compounds that contain the structure SO2NH2.

Testis: The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.

Thrombophlebitis: Inflammation of a vein associated with a blood clot (THROMBUS).

Thyroid Gland: A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.

Tobacco: A plant genus of the family SOLANACEAE. Members contain NICOTINE and other biologically active chemicals; its dried leaves are used for SMOKING.

Tongue: A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.

Trachea: The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi.

Transplants: Organs, tissues, or cells taken from the body for grafting into another area of the same body or into another individual.

Tuberculosis: Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.

Ureter: One of a pair of thick-walled tubes that transports urine from the KIDNEY PELVIS to the URINARY BLADDER.

Urinary Calculi: Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.

Uterus: The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.