2027 ICD-10-CM Diagnosis Code T44.4X3APoisoning by predominantly alpha-adrenoreceptor agonists, assault, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T44

ICD-10-CM T44.4X3A
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T44.4X3A is a billable ICD-10-CM diagnosis code for poisoning by predominantly alpha-adrenoreceptor agonists, assault, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, assault; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

Code Identity

ICD-10-CM Code
T44.4X3A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by predominantly alpha-adrenoreceptor agonists, assault, initial encounter
Short Description
Poisoning by predom alpha-adrenocpt agonists, assault, init
Parent Code
Poisoning by predominantly alpha-adrenoreceptor agonists, assault

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT44Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system
This CodeT44.4X3APoisoning by predominantly alpha-adrenoreceptor agonists, assault, initial encounter

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (T44). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T44.4X3A: its own notes plus those printed at T44, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T44 Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system applies to 198 codes
  • The appropriate 7th character is to be added to each code from category T44
  • Ainitial encounter this code
  • Dsubsequent encounter
  • Ssequela

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name T44.4X3A, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming T44.4X3A: they are not reported together with it, unless the two conditions are unrelated.

  • T46 Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system
    poisoning by, adverse effect of and underdosing of metaraminol (T44.4) names T44.4, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT022
External cause codes: intent of injury, assault
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Etilefrine

    a phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.
  • Metaraminol

    a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. it has been used primarily as a vasoconstrictor in the treatment of hypotension.
  • Methoxamine

    an alpha-1 adrenergic agonist that causes prolonged peripheral vasoconstriction.
  • Norepinephrine

    precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. norepinephrine is the principal transmitter of most postganglionic sympathetic fibers, and of the diffuse projection system in the brain that arises from the locus ceruleus. it is also found in plants and is used pharmacologically as a sympathomimetic.
  • Phenylephrine

    an alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Agonist::predominantly::alpha-adrenoreceptorT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
AplonidineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
Apraclonidine (hydrochloride)T44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
CyclopentamineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
EtilefrineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
GepefrineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
LevarterenolT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
MetaraminolT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
MethoxamineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
NoradrenalineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
NorepinephrineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
NorfenefrineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
OxedrineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
ParedrineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
PhenylephrineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
PrivineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6
Propyl::hexadrineT44.4X1T44.4X2T44.4X3T44.4X4T44.4X5T44.4X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T44.4X3A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
971.2 Poison-sympathomimetics
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E962.0 Assault-pois w medic agt
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T44.4X3AOverview

Is T44.4X3A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by predominantly alpha-adrenoreceptor agonists, assault, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character A in T44.4X3A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by predominantly alpha-adrenoreceptor agonists, assault, such as an emergency visit or first evaluation.

What MS-DRG does T44.4X3A group to?

When poisoning by predominantly alpha-adrenoreceptor agonists, assault, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 918, 917, with relative weights from 0.8716 to 1.5698 depending on complications. Higher weights mean higher Medicare reimbursement.

Can T44.4X3A be reported with a code from O29.3?

Not as a rule. The Excludes1 note at block T36-T50, which applies to T44.4X3A, lists "toxic reaction to local anesthesia in pregnancy (O29.3-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of T44.4X3A?

Under the General Equivalence Mappings, poisoning by predominantly alpha-adrenoreceptor agonists, assault, initial encounter converts to ICD-9-CM 971.2 (poison-sympathomimetics) and E962.0 (assault-pois w medic agt). The mapping is approximate, so confirm the match fits the documentation.