2026 ICD-10-CM Diagnosis Code T40.1X4APoisoning by heroin, undetermined, initial encounter

ICD-10-CM CodesS00–T88T36-T50T40

ICD-10-CM T40.1X4A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T40.1X4A is a billable ICD-10-CM diagnosis code for poisoning by heroin, undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. Coders also document this condition as nephropathy caused by heroin. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by drug; and Opioid-related disorders.

Code Identity

ICD-10-CM Code
T40.1X4A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by heroin, undetermined, initial encounter
Short Description
Poisoning by heroin, undetermined, initial encounter
Same as the full description in the CMS dataset.
Parent Code
Poisoning by heroin, undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT40Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens]
This CodeT40.1X4APoisoning by heroin, undetermined, initial encounter

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Nephropathy caused by heroin

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] (T40). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT023
External cause codes: intent of injury, undetermined
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR MBD018
Opioid-related disorders
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Heroin

    a narcotic analgesic that may be habit-forming. it is a controlled substance (opium derivative) listed in the u.s. code of federal regulations, title 21 parts 329.1, 1308.11 (1987). sale is forbidden in the united states by federal statute. (merck index, 11th ed)
  • Heroin Dependence

    strong dependence or addiction, both physiological and emotional, upon heroin.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AcetomorphineT40.1X1T40.1X2T40.1X3T40.1X4
DiacetylmorphineT40.1X1T40.1X2T40.1X3T40.1X4
DiamorphineT40.1X1T40.1X2T40.1X3T40.1X4
HeroinT40.1X1T40.1X2T40.1X3T40.1X4

Patient EducationClinical

Heroin

Heroin is an illegal, very addictive opioid drug. It's made from morphine, which comes from the seedpod of opium poppy plants. These plants grow in Southeast and Southwest Asia, Mexico, and Colombia. Heroin can be a white or brown powder, or a black sticky substance known as black tar heroin.

The full article covers:

  • What is heroin?
  • How do people use heroin?
  • What are the short-term effects of heroin?
  • What are the long-term effects of heroin?
  • Can a person overdose on heroin?
  • How can a heroin overdose be treated?
  • What are the treatments for heroin use disorder?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T40.1X4A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
965.01 Poisoning-heroin
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E980.0 Undeterm pois-analgesics
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T40.1X4AOverview

Is T40.1X4A (Poisoning by heroin, undetermined) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by heroin, undetermined, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T40.1X4A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by heroin, undetermined, such as an emergency visit or first evaluation.

What MS-DRG does T40.1X4A group to?

When poisoning by heroin, undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T40.1X4A?

Under the General Equivalence Mappings, poisoning by heroin, undetermined, initial encounter converts to ICD-9-CM 965.01 (poisoning-heroin) and E980.0 (undeterm pois-analgesics). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.