Version 2024

2024 ICD-10-CM Diagnosis Code F11.2

Opioid dependence

ICD-10-CM Code:
F11.2
ICD-10 Code for:
Opioid dependence
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Mental and behavioural disorders
    (F01–F99)
    • Mental and behavioral disorders due to psychoactive substance use
      (F10-F19)
      • Opioid related disorders
        (F11)

F11.2 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of opioid dependence. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Opioid dependence

Non-specific codes like F11.2 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for opioid dependence:

  • Use F11.20 for Opioid dependence, uncomplicated - BILLABLE CODE

  • Use F11.21 for Opioid dependence, in remission - BILLABLE CODE

  • F11.22 for Opioid dependence with intoxication - NON-BILLABLE CODE

  • Use F11.220 for Opioid dependence with intoxication, uncomplicated - BILLABLE CODE

  • Use F11.221 for Opioid dependence with intoxication delirium - BILLABLE CODE

  • Use F11.222 for Opioid dependence with intoxication with perceptual disturbance - BILLABLE CODE

  • Use F11.229 for Opioid dependence with intoxication, unspecified - BILLABLE CODE

  • Use F11.23 for Opioid dependence with withdrawal - BILLABLE CODE

  • Use F11.24 for Opioid dependence with opioid-induced mood disorder - BILLABLE CODE

  • F11.25 for Opioid dependence with opioid-induced psychotic disorder - NON-BILLABLE CODE

  • Use F11.250 for Opioid dependence with opioid-induced psychotic disorder with delusions - BILLABLE CODE

  • Use F11.251 for Opioid dependence with opioid-induced psychotic disorder with hallucinations - BILLABLE CODE

  • Use F11.259 for Opioid dependence with opioid-induced psychotic disorder, unspecified - BILLABLE CODE

  • F11.28 for Opioid dependence with other opioid-induced disorder - NON-BILLABLE CODE

  • Use F11.281 for Opioid dependence with opioid-induced sexual dysfunction - BILLABLE CODE

  • Use F11.282 for Opioid dependence with opioid-induced sleep disorder - BILLABLE CODE

  • Use F11.288 for Opioid dependence with other opioid-induced disorder - BILLABLE CODE

  • Use F11.29 for Opioid dependence with unspecified opioid-induced disorder - BILLABLE CODE

Patient Education


Opioids and Opioid Use Disorder (OUD)

What are opioids?

Opioids, sometimes called narcotics, are a type of drug. They include strong prescription pain relievers such as oxycodone, hydrocodone, fentanyl, and tramadol. The illegal drug heroin is also an opioid. Some opioids are made from the opium plant, and others are synthetic (man-made).

A health care provider may give you a prescription opioid to reduce pain after you have had a major injury or surgery. You may get them if you have severe pain from health conditions like cancer. Some providers prescribe them for chronic pain.

What are the side effects and risks of opioids?

Opioids can cause side effects such as drowsiness, mental fog, nausea, and constipation. They may also cause slowed breathing, which can lead to overdose deaths. If someone has signs of an overdose, call 911. These signs may include:

  • Very small pupils of the eyes
  • Falling asleep or loss of consciousness
  • Slow, shallow breathing
  • Choking or gurgling sounds
  • Vomiting
  • Limp body
  • Pale, blue, or cold skin
  • Faint heartbeat
  • Purple lips and fingernails

When using opioids, there is also a risk of opioid use disorder (OUD).

What is opioid use disorder (OUD)?

Opioid use disorder (OUD) means that you have a problematic pattern of using opioids. The pattern causes a lot of distress and impairment (meaning that it causes problems in and interferes with your daily life). Instead of OUD, sometimes people use the terms "opioid dependence" and "opioid addiction." Dependence means feeling withdrawal symptoms when not taking the drug. Addiction is a chronic brain disease that causes a person to compulsively seek out drugs, even though they cause harm.

The risk of OUD is higher if you misuse the medicines. Misuse can include taking more than your prescribed dose or taking it more often, using it to get high, or taking someone else's opioids.

Opioid use disorder and overdoses are serious public health problems in the United States. As more people misuse opioids, more women are misusing opioids during pregnancy. This can lead to health risks for the mother and baby. The baby may be born with neonatal abstinence syndrome (NAS). NAS is a group of withdrawal symptoms that a baby has after being exposed to drugs during pregnancy.

Another problem with increased opioid misuse is that it can also lead to more heroin use. There are some people who switch from prescription opioids to heroin because heroin may be cheaper and easier to get.

How are opioid use disorder (OUD) and opioid overdose treated?

There are effective medicines to treat OUD. Using medicines to treat OUD is called medications for opioid use disorder (MOUD). MOUD can help you stop using the drug, get through withdrawal, and cope with cravings. It is often combined with behavioral therapy and counseling. Having support from family and friends can also help.

There is also a medicine called naloxone which can treat opioid overdoses. It can reverse the effects of the overdose and prevent death if it is given quickly.

How can I prevent problems when taking prescription opioids?

To prevent problems with prescription opioids, be sure to follow your doctor's instructions when taking them. Do not share your medicines with anyone else. Contact your doctor if you have any concerns about taking the medicines.

NIH: National Institute on Drug Abuse


[Learn More in MedlinePlus]

Prescription Drug Misuse

If you take a medicine in a way that is different from what the doctor prescribed, it is called prescription drug misuse. It could be:

  • Taking a medicine that was prescribed for someone else
  • Taking a larger dose than you are supposed to
  • Taking the medicine in a different way than you are supposed to. This might be crushing tablets and then snorting or injecting them.
  • Using the medicine for another purpose, such as getting high

Misusing some prescription drugs can lead to addiction. These include opioids, sedatives, tranquilizers, and stimulants.

Every medicine has some risk of side effects. Doctors take this into account when prescribing medicines. People who misuse these drugs may not understand the risks. The medicines may not be safe for them, especially at higher doses or when taken with other medicines.

NIH: National Institute on Drug Abuse


[Learn More in MedlinePlus]

Opioid addiction

Opioid addiction is a long-lasting (chronic) disease that can cause major health, social, and economic problems. Opioids are a class of drugs that act in the nervous system to produce feelings of pleasure and pain relief. Some opioids are legally prescribed by healthcare providers to manage severe and chronic pain. Commonly prescribed opioids include oxycodone, fentanyl, buprenorphine, methadone, oxymorphone, hydrocodone, codeine, and morphine. Some other opioids, such as heroin, are illegal drugs of abuse.

Opioid addiction is characterized by a powerful, compulsive urge to use opioid drugs, even when they are no longer required medically. Opioids have a high potential for causing addiction in some people, even when the medications are prescribed appropriately and taken as directed. Many prescription opioids are misused or diverted to others. Individuals who become addicted may prioritize getting and using these drugs over other activities in their lives, often negatively impacting their professional and personal relationships. It is unknown why some people are more likely to become addicted than others.

Opioids change the chemistry of the brain and lead to drug tolerance, which means that over time the dose needs to be increased to achieve the same effect. Taking opioids over a long period of time produces dependence, such that when people stop taking the drug, they have physical and psychological symptoms of withdrawal (such as muscle cramping, diarrhea, and anxiety). Dependence is not the same thing as addiction; although everyone who takes opioids for an extended period will become dependent, only a small percentage also experience the compulsive, continuing need for the drug that characterizes addiction.

Opioid addiction can cause life-threatening health problems, including the risk of overdose. Overdose occurs when high doses of opioids cause breathing to slow or stop, leading to unconsciousness and death if the overdose is not treated immediately. Both legal and illegal opioids carry a risk of overdose if a person takes too much of the drug, or if opioids are combined with other drugs (particularly tranquilizers called benzodiazepines).


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.