2026 ICD-10-CM Diagnosis Code T38.7X5AAdverse effect of androgens and anabolic congeners, initial encounter
T38.7X5A is a billable ICD-10-CM diagnosis code for adverse effect of androgens and anabolic congeners, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Adverse effects of drugs and medicaments, initial encounter.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for T38.7X5A.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- 46,XX disorder of sex development caused by testosterone and/or testosterone derivative
- Anabolic steroids adverse reaction
- Androgen adverse reaction
- Androgen-induced testicular atrophy
- Anti-androgens adverse reaction
- Atrophy of testis
- Bicalutamide adverse reaction
- Drostanolone propionate adverse reaction
- Intramuscular testosterone adverse reaction
- Mesterolone adverse reaction
- Methyltestosterone adverse reaction
- Nandrolone adverse reaction
- Oral testosterone adverse reaction
- Oxymetholone adverse reaction
- Stanozolol adverse reaction
- Testosterone adverse reaction
- Testosterone implant adverse reaction
- Testosterone patch adverse reaction
- Tibolone adverse reaction
Coding GuidelinesGuidance
When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified (T38). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Androsterone
a metabolite of testosterone or androstenedione with a 3-alpha-hydroxyl group and without the double bond. the 3-beta hydroxyl isomer is epiandrosterone.Glucuronosyltransferase
a family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. they function as drug-metabolizing enzymes that catalyze the conjugation of udpglucuronic acid to a variety of endogenous and exogenous compounds. ec 2.4.1.17.Ethylestrenol
an anabolic steroid with some progestational activity and little androgenic effect.Norethandrolone
a synthetic hormone with anabolic and androgenic properties and moderate progestational activity.Fluoxymesterone
an anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.Mesterolone
17 beta-hydroxy-1 alpha-methyl-5 alpha-androstan-3-one. a synthetic steroid with anabolic and androgenic activities.Methandriol
a synthetic steroid with anabolic and androgenic properties. (from martindale, the extra pharmacopoeia, 30th ed, p1188)Methandrostenolone
a synthetic steroid with anabolic properties that are more pronounced than its androgenic effects. it has little progestational activity. (from martindale, the extra pharmacopoeia, 30th ed, p1188)Methenolone
a synthetic steroid that has been used for its anabolic action.Methyltestosterone
a synthetic hormone used for androgen replacement therapy and as an hormonal antineoplastic agent (antineoplastic agents, hormonal).Nandrolone
c18 steroid with androgenic and anabolic properties. it is generally prepared from alkyl ethers of estradiol to resemble testosterone but less one carbon at the 19 position.Nandrolone Decanoate
decanoic acid ester of nandrolone that is used as an anabolic agent to prevent or treat wasting syndrome associated with severe chronic illness or hiv infection (hiv wasting syndrome). it may also be used in the treatment of postmenopausal osteoporosis.Oxandrolone
a synthetic hormone with anabolic and androgenic properties.Oxymetholone
a synthetic hormone with anabolic and androgenic properties. it is used mainly in the treatment of anemias. according to the fourth annual report on carcinogens (ntp 85-002), this compound may reasonably be anticipated to be a carcinogen. (from merck index, 11th ed)Stanozolol
a synthetic steroid that has anabolic and androgenic properties. (from martindale, the extra pharmacopoeia, 30th ed, p1194)Testolactone
an antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.17-Hydroxysteroid Dehydrogenases
a class of enzymes that catalyzes the oxidation of 17-hydroxysteroids to 17-ketosteroids. ec 1.1.-.3-Oxo-5-alpha-Steroid 4-Dehydrogenase
an enzyme that catalyzes the reduction of testosterone to 5-alpha dihydrotestosterone.5-alpha Reductase Inhibitors
drugs that inhibit 3-oxo-5-alpha-steroid 4-dehydrogenase. they are commonly used to reduce the production of dihydrotestosterone.Clusterin
a highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as cancer; apoptosis; and various neurological disorders. clusterin is ubiquitously expressed and appears to function as a secreted molecular chaperone.Receptors, Androgen
proteins, generally found in the cytoplasm, that specifically bind androgens and mediate their cellular actions. the complex of the androgen and receptor migrates to the cell nucleus where it induces transcription of specific segments of dna.Sex Hormone-Binding Globulin
a glycoprotein migrating as a beta-globulin. its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. the protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. sex hormone-binding protein has the same amino acid sequence as androgen-binding protein. they differ by their sites of synthesis and post-translational oligosaccharide modifications.Steroid 16-alpha-Hydroxylase
a liver microsomal cytochrome p450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and nadph-ferrihemoprotein reductase. this enzyme is encoded by a number of genes from several cyp2 subfamilies.Testosterone
a potent androgenic steroid and major product secreted by the leydig cells of the testis. its production is stimulated by luteinizing hormone from the pituitary gland. in turn, testosterone exerts feedback control of the pituitary lh and fsh secretion. depending on the tissues, testosterone can be further converted to dihydrotestosterone or estradiol.Testosterone Congeners
steroidal compounds related to testosterone, the major mammalian male sex hormone. testosterone congeners include important testosterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with androgenic activities.Testosterone Propionate
an ester of testosterone with a propionate substitution at the 17-beta position.Zeranol
a non-steroidal estrogen analog.
Table of Drugs and ChemicalsClinical
Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.
Patient EducationClinical
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
The full article covers:
- What is a drug interaction?
- What are side effects?
- What are drug allergies?
- How can I stay safe when taking medicines?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert T38.7X5A to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T38.7X5AOverview
Is T38.7X5A (Adverse effect of androgens and anabolic congeners) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report adverse effect of androgens and anabolic congeners, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character A in T38.7X5A mean?
The final character A marks the initial encounter: use it while the patient is receiving active treatment for adverse effect of androgens and anabolic congeners, such as an emergency visit or first evaluation.
What MS-DRG does T38.7X5A group to?
On inpatient claims, adverse effect of androgens and anabolic congeners, initial encounter maps to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.
Can T38.7X5A be a principal diagnosis?
No. The Medicare Code Editor rejects this code as a principal diagnosis because adverse effect of androgens and anabolic congeners, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.
What is the ICD-9 equivalent of T38.7X5A?
Under the General Equivalence Mappings, adverse effect of androgens and anabolic congeners, initial encounter converts to ICD-9-CM 995.29 (adv eff med/biol NEC/NOS) and E932.1 (adv eff androgens). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
