2027 ICD-10-CM Diagnosis Code T37.8X6AUnderdosing of other specified systemic anti-infectives and antiparasitics, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T37

ICD-10-CM T37.8X6A
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T37.8X6A is a billable ICD-10-CM diagnosis code for underdosing of other specified systemic anti-infectives and antiparasitics, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T37.8X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of other specified systemic anti-infectives and antiparasitics, initial encounter
Short Description
Underdosing of systemic anti-infect/parasit, init
Parent Code
Underdosing of other specified systemic anti-infectives and antiparasitics

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT37Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics
This CodeT37.8X6AUnderdosing of other specified systemic anti-infectives and antiparasitics, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T37.8X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (T37). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T37.8X6A: its own notes plus those printed at T37.8, T37, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From T37.8 Poisoning by, adverse effect of and underdosing of other specified systemic anti-infectives and antiparasitics applies to 18 codes
From T37 Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics applies to 144 codes
  • anti-infectives topically used for ear, nose and throat (T49.6-)
  • anti-infectives topically used for eye (T49.5-)
  • locally applied anti-infectives NEC (T49.0-)
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T37 Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics applies to 144 codes
  • The appropriate 7th character is to be added to each code from category T37
  • Ainitial encounter this code
  • Dsubsequent encounter
  • Ssequela

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name T37.8X6A, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming T37.8X6A: they are not reported together with it, unless the two conditions are unrelated.

  • T37.2 Poisoning by, adverse effect of and underdosing of antimalarials and drugs acting on other blood protozoa
    hydroxyquinoline derivatives (T37.8-) names T37.8-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AkritoinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Anti-infective NEC::arsenicalT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Anti-infective NEC::heavy metals NECT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Antimony (compounds) (vapor) NEC::anti-infectivesT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Antimony (compounds) (vapor) NEC::potassium (sodium) tartrateT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Antimony (compounds) (vapor) NEC::tartratedT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Antiparasitic drug (systemic)::specified NECT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Arsenic, arsenicals (compounds) (dust) (vapor) NEC::anti-infectivesT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Arsphenamine (silver)T37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
BismarsenT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Bismuth salts::anti-infectivesT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Bismuth salts::subsalicylateT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Bismuth salts::sulfarsphenamineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
BithionolT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
BroxyquinolineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
ChiniofonT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
CinoxacinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
ClioquinolT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
CroconazoleT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
DichlorhydroxyquinolineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
DiiodohydroxyquinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
DiiodohydroxyquinolineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
DiodoquinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Disinfectant::intestinalT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
FloraquinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
FluconazoleT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
FlucytosineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
FlumequineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
FlunidazoleT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
FluorocytosineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
FurazolidoneT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Hexamine (mandelate)T37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
HexetidineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
HydroxychloroquineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Hydroxyquinoline (derivatives) NECT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
IodobismitolT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
IodochlorhydroxyquinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
IodochlorhydroxyquinolineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
IodoquinolT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
ItraconazoleT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Lead (dust) (fumes) (vapor) NEC::anti-infectivesT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Mandelic acidT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
MapharsenT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Meglumine::antimoniateT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Mercury, mercurial, mercuric, mercurous (compounds) (cyanide) (fumes) (nonmedicinal) (vapor) NEC::anti-infective::systemicT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Methenamine (mandelate)T37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Methyl::glucamine antimonateT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
MetronidazoleT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Nalidixic acidT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
NeoarsphenamineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
NeosalvarsanT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
NeosilversalvarsanT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
NifuratelT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
NifurtoinolT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
NitrofurantoinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
NitroxolineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Oxolinic acidT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Oxyquinoline (derivatives)T37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
PefloxacinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Pipemidic acidT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Piromidic acidT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Potassium (salts) NEC::antimony ' tartrate'T37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
QuiniobineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Quinoline (derivatives) NECT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
RosoxacinT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Salvarsan 606 (neosilver) (silver)T37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Silver::arsphenamineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Silver::salvarsanT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Sodium::cacodylate (nonmedicinal) NEC::anti-infectiveT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
StovarsalT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
SulfarsphenamineT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Tartar emeticT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Tartrated antimony (anti-infective)T37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
ThiobismolT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
ThiocarbarsoneT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Tin (chloride) (dust) (oxide) NEC::anti-infectivesT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
TrimethoprimT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
Urinary anti-infectiveT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
VioformT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6
XibornolT37.8X1T37.8X2T37.8X3T37.8X4T37.8X5T37.8X6

Patient EducationClinical

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T37.8X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T37.8X6AOverview

Is T37.8X6A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of other specified systemic anti-infectives and antiparasitics, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character A in T37.8X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of other specified systemic anti-infectives and antiparasitics, such as an emergency visit or first evaluation.

What MS-DRG does T37.8X6A group to?

On inpatient claims, underdosing of other specified systemic anti-infectives and antiparasitics, initial encounter maps to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.

Can T37.8X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of other specified systemic anti-infectives and antiparasitics, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Can T37.8X6A be reported with a code from T37.2?

Not as a rule. The Excludes1 note at T37.8, which applies to T37.8X6A, lists "antimalarial drugs (T37.2-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).