2026 ICD-10-CM Diagnosis Code T36.5X2SPoisoning by aminoglycosides, intentional self-harm, sequela
T36.5X2S is a billable ICD-10-CM diagnosis code for poisoning by aminoglycosides, intentional self-harm, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Mental and substance use disorders; sequela; and Poisoning/toxic effect/adverse effects/underdosing, sequela.
Code Identity
Code Classification
Present on Admission (POA)Billing
T36.5X2S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Gentamicin overdose
- Gentamicin poisoning
- Intentional gentamicin overdose
- Intentional gentamicin poisoning
- Intentional kanamycin overdose
- Intentional kanamycin poisoning
- Intentional netilmicin overdose
- Intentional netilmicin poisoning
- Intentional spectinomycin overdose
- Intentional spectinomycin poisoning
- Intentional streptomycin overdose
- Intentional streptomycin poisoning
- Intentional tobramycin overdose
- Intentional tobramycin poisoning
- Kanamycin overdose
- Netilmicin overdose
- Netilmicin poisoning
- Poisoning by kanamycin
- Poisoning by streptomycin
- Spectinomycin overdose
- Spectinomycin poisoning
- Streptomycin overdose
- Tobramycin overdose
- Tobramycin poisoning
Coding GuidelinesGuidance
When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of systemic antibiotics (T36). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Amikacin
a broad-spectrum antibiotic derived from kanamycin. it is reno- and oto-toxic like the other aminoglycoside antibiotics.Kanamycin Kinase
a class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (aminoglycosides) by regiospecific phosphorylation of the 3' and/or 5' hydroxyl.Dibekacin
analog of kanamycin with antitubercular as well as broad-spectrum antimicrobial properties.Framycetin
a component of neomycin that is produced by streptomyces fradiae. on hydrolysis it yields neamine and neobiosamine b. (from merck index, 11th ed)Kanamycin
antibiotic complex produced by streptomyces kanamyceticus from japanese soil. comprises 3 components: kanamycin a, the major component, and kanamycins b and c, the minor components.Kanamycin Resistance
nonsusceptibility of bacteria to the antibiotic kanamycin, which can bind to their 70s ribosomes and cause misreading of messenger rna.Netilmicin
semisynthetic 1-n-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity.Novobiocin
an antibiotic compound derived from streptomyces niveus. it has a chemical structure similar to coumarin. novobiocin binds to dna gyrase, and blocks adenosine triphosphatase (atpase) activity. (from reynolds, martindale the extra pharmacopoeia, 30th ed, p189)Paromomycin
an aminoglycoside antibacterial and antiprotozoal agent produced by species of streptomyces.Ribostamycin
a broad-spectrum antimicrobial isolated from streptomyces ribosifidicus.Sisomicin
antibiotic produced by micromonospora inyoensis. it is closely related to gentamicin c1a, one of the components of the gentamicin complex (gentamicins).Spectinomycin
an antibiotic produced by streptomyces spectabilis. it is active against gram-negative bacteria and used for the treatment of gonorrhea.Tobramycin
an aminoglycoside, broad-spectrum antibiotic produced by streptomyces tenebrarius. it is effective against gram-negative bacteria, especially the pseudomonas species. it is a 10% component of the antibiotic complex, nebramycin, produced by the same species.Tobramycin, Dexamethasone Drug Combination
a topical preparation of tobramycin and dexamethasone that is used for treating or preventing superficial bacterial infections of the eye.
Table of Drugs and ChemicalsClinical
Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.
Patient EducationClinical
Antibiotics
Antibiotics are medicines that fight bacterial infections in people and animals. They work by killing the bacteria or by making it hard for the bacteria to grow and multiply.
The full article covers:
- What are antibiotics?
- What do antibiotics treat?
- Do antibiotics treat viral infections?
- What are the side effects of antibiotics?
- Why is it important to take antibiotics only when they're needed?
- How do I use antibiotics correctly?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert T36.5X2S to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T36.5X2SOverview
Is T36.5X2S (Poisoning by aminoglycosides, intentional self-harm) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by aminoglycosides, intentional self-harm, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character S in T36.5X2S mean?
The final character S makes this a sequela code: it reports a lingering problem that remains after the poisoning by aminoglycosides, intentional self-harm itself has resolved, not the original event.
What MS-DRG does T36.5X2S group to?
When poisoning by aminoglycosides, intentional self-harm, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.
Is T36.5X2S exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for poisoning by aminoglycosides, intentional self-harm, sequela on inpatient claims.
What is the ICD-9 equivalent of T36.5X2S?
Under the General Equivalence Mappings, poisoning by aminoglycosides, intentional self-harm, sequela converts to ICD-9-CM 909.0 (late eff drug poisoning) and E959 (late eff of self-injury). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
